| CMF-30783 | RYR1 | down-regulates | LHX1 | represses | R-2962 | 17 | 5 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-30784 | RYR1 | down-regulates | LHX1 | represses | R-2971 | 17 | 5 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-30790 | RYR1 | down-regulates | ALX4 | represses | R-2908 | 20 | 3 | Drugs (3) |
| CMF-30793 | RYR1 | up-regulates | NR3C1 | activates | R-2032 | 21 | 5 | Drugs (90) Regulator Drugs (0)Regulon Drugs (90)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, RUPATADINE, DOXYLAMINE SUCCINATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, IMSIDOLIMAB, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, EBASTINE, CINNARIZINE, HYDROXYZINE, LORATADINE, LY2624803, BELZUTIFAN, PHENIRAMINE MALEATE, TRIPROLIDINE HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, CETIRIZINE, SPESOLIMAB, METHDILAZINE |
| CMF-30795 | RYR1 | up-regulates | NR3C1 | activates | R-2047 | 21 | 5 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-30799 | RYR1 | down-regulates | STAT4 | represses | R-1144 | 16 | 5 | Drugs (92) Regulator Drugs (0)Regulon Drugs (92)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, RUPATADINE, DOXYLAMINE SUCCINATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, IMSIDOLIMAB, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, EBASTINE, CINNARIZINE, OLECLUMAB, HYDROXYZINE, LORATADINE, LY2624803, BELZUTIFAN, PHENIRAMINE MALEATE, TRIPROLIDINE HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, OCRIPLASMIN, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, CETIRIZINE, SPESOLIMAB, METHDILAZINE |
| CMF-30802 | RYR1 | down-regulates | TBR1 | represses | R-2743 | 3 | 1 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-30807 | RYR1 | down-regulates | PGR | represses | R-3403 | 8 | 1 | Drugs (22) Regulator Drugs (21)NORETHINDRONE, ULIPRISTAL ACETATE, ETONOGESTREL, NORGESTREL, DYDROGESTERONE, DESOGESTREL, NORGESTIMATE, PROGESTERONE, HYDROXYPROGESTERONE CAPROATE, MEGESTROL ACETATE, NORELGESTROMIN, ULIPRISTAL, NORETHINDRONE ACETATE, LEVONORGESTREL, ASOPRISNIL, LONAPRISAN, ONAPRISTONE, MEDROXYPROGESTERONE ACETATE, PF-05019702, VILAPRISAN, TELAPRISTONE ACETATE Regulon Drugs (1)TOSEDOSTAT |
| CMF-30808 | RYR1 | down-regulates | LHX3 | represses | R-2006 | 24 | 6 | Drugs (3) |
| CMF-30810 | RYR1 | down-regulates | LHX3 | represses | R-1996 | 24 | 6 | Drugs (2) |
| CMF-30811 | RYR1 | down-regulates | LHX3 | represses | R-1994 | 24 | 6 | Drugs (22) Regulator Drugs (0)Regulon Drugs (22)CISATRACURIUM, CISATRACURIUM BESYLATE, SUXAMETHONIUM, PRAMLINTIDE, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, MIVACURIUM, SULTHIAME, DORZOLAMIDE, ROCURONIUM BROMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, MIVACURIUM CHLORIDE, PRAMLINTIDE ACETATE, TISOTUMAB VEDOTIN, TOPIRAMATE, VANTICTUMAB, ACETAZOLAMIDE SODIUM, POLMACOXIB, ROCURONIUM, DAVALINTIDE |
| CMF-30812 | RYR1 | down-regulates | LHX3 | represses | R-1997 | 24 | 6 | Drugs (33) Regulator Drugs (0)Regulon Drugs (33)SAVOLITINIB, TELISOTUZUMAB VEDOTIN, AMUVATINIB, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, MK-8033, AMG-337, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, JNJ-38877605, GLESATINIB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, GOLVATINIB |
| CMF-30818 | RYR1 | up-regulates | CEBPZ | activates | R-2995 | 12 | 4 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)TAS0612 |
| CMF-30820 | RYR1 | up-regulates | CEBPZ | activates | R-2994 | 12 | 4 | Drugs (33) Regulator Drugs (0)Regulon Drugs (33)SAVOLITINIB, TELISOTUZUMAB VEDOTIN, AMUVATINIB, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, MK-8033, AMG-337, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, JNJ-38877605, GLESATINIB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, GOLVATINIB |
| CMF-30823 | RYR1 | down-regulates | POU4F2 | represses | R-2783 | 13 | 6 | Drugs (7) |
| CMF-30826 | RYR1 | down-regulates | POU4F2 | represses | R-2782 | 13 | 6 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-30827 | RYR1 | down-regulates | POU4F2 | represses | R-2788 | 13 | 6 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-30831 | RYR1 | up-regulates | CEBPG | activates | R-1036 | 23 | 7 | Drugs (91) Regulator Drugs (0)Regulon Drugs (91)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, RUPATADINE, DOXYLAMINE SUCCINATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, IMSIDOLIMAB, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, EBASTINE, CINNARIZINE, HYDROXYZINE, LORATADINE, LY2624803, BELZUTIFAN, PHENIRAMINE MALEATE, TRIPROLIDINE HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, OCRIPLASMIN, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, CETIRIZINE, SPESOLIMAB, METHDILAZINE |
| CMF-30832 | RYR1 | up-regulates | CEBPG | activates | R-1037 | 23 | 7 | Drugs (8) |
| CMF-30836 | RYR1 | down-regulates | CEBPE | represses | R-2671 | 13 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-30838 | RYR1 | down-regulates | CEBPE | represses | R-2670 | 13 | 3 | Drugs (5) |
| CMF-30840 | RYR1 | down-regulates | IRF4 | represses | R-3772 | 5 | 2 | Drugs (1) |
| CMF-30844 | RYR1 | down-regulates | FOXA2 | represses | R-2021 | 11 | 4 | Drugs (93) Regulator Drugs (0)Regulon Drugs (93)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, RUPATADINE, DOXYLAMINE SUCCINATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, IMSIDOLIMAB, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, EBASTINE, CINNARIZINE, OLECLUMAB, HYDROXYZINE, LORATADINE, LY2624803, PHENIRAMINE MALEATE, TRIPROLIDINE HYDROCHLORIDE, NERAMEXANE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, NERAMEXANE MESYLATE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, OCRIPLASMIN, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, CETIRIZINE, SPESOLIMAB, METHDILAZINE |
| CMF-43301 | RYR1 | down-regulates | hsa-mir-551b | represses | R-218 | 22 | 6 | Drugs (3) |
| CMF-43302 | RYR1 | down-regulates | hsa-mir-551b | represses | R-2459 | 22 | 6 | Drugs (3) |
| CMF-43303 | RYR1 | down-regulates | hsa-mir-551b | represses | R-2760 | 22 | 6 | Drugs (3) |
| CMF-43304 | RYR1 | down-regulates | hsa-mir-551b | represses | R-2892 | 22 | 6 | Drugs (3) |
| CMF-43305 | RYR1 | down-regulates | hsa-mir-551b | represses | R-3643 | 22 | 6 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-43306 | RYR1 | down-regulates | hsa-mir-551b | represses | R-2006 | 22 | 6 | Drugs (3) |
| CMF-43307 | RYR1 | down-regulates | hsa-mir-30d | represses | R-2395 | 29 | 8 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |
| CMF-43308 | RYR1 | down-regulates | hsa-mir-30d | represses | R-635 | 29 | 8 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |
| CMF-43309 | RYR1 | down-regulates | hsa-mir-30d | represses | R-2849 | 29 | 8 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |
| CMF-43310 | RYR1 | down-regulates | hsa-mir-30d | represses | R-983 | 29 | 8 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |
| CMF-43311 | RYR1 | down-regulates | hsa-mir-30d | represses | R-1138 | 29 | 8 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |
| CMF-43312 | RYR1 | down-regulates | hsa-mir-30d | represses | R-1178 | 29 | 8 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |
| CMF-43313 | RYR1 | down-regulates | hsa-mir-30d | represses | R-1234 | 29 | 8 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |
| CMF-43314 | RYR1 | down-regulates | hsa-mir-30d | represses | R-1916 | 29 | 8 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |
| CMF-43315 | RYR1 | down-regulates | hsa-mir-500 | represses | R-2395 | 2 | 1 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |