| CMF-04179 | RBPJL | down-regulates | FGF9 | represses | R-1768 | 4 | 1 | Drugs (1) |
| CMF-04180 | RBPJL | down-regulates | LHX2 | represses | R-3708 | 7 | 3 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)EMRICASAN |
| CMF-04183 | RBPJL | down-regulates | VAX2 | represses | R-1271 | 7 | 2 | Drugs (7) |
| CMF-04186 | RBPJL | down-regulates | LHX1 | represses | R-2961 | 17 | 7 | Drugs (84) Regulator Drugs (0)Regulon Drugs (84)IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, MELOXICAM, BROMFENAC SODIUM, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB |
| CMF-04187 | RBPJL | down-regulates | LHX1 | represses | R-2963 | 17 | 7 | Drugs (34) Regulator Drugs (0)Regulon Drugs (34)SAVOLITINIB, TELISOTUZUMAB VEDOTIN, AMUVATINIB, BIRINAPANT, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, MK-8033, AMG-337, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, JNJ-38877605, GLESATINIB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, GOLVATINIB |
| CMF-04188 | RBPJL | down-regulates | LHX1 | represses | R-2971 | 17 | 7 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-04191 | RBPJL | down-regulates | SOX4 | represses | R-2053 | 15 | 3 | Drugs (9) |
| CMF-04195 | RBPJL | down-regulates | SOX12 | represses | R-1100 | 18 | 5 | Drugs (2) |
| CMF-04196 | RBPJL | down-regulates | SOX12 | represses | R-1102 | 18 | 5 | Drugs (88) Regulator Drugs (0)Regulon Drugs (88)IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, CANAKINUMAB, MELOXICAM, BROMFENAC SODIUM, RILONACEPT, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, GEVOKIZUMAB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, LUTIKIZUMAB, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB |
| CMF-04197 | RBPJL | down-regulates | SOX12 | represses | R-1107 | 18 | 5 | Drugs (4) |
| CMF-04198 | RBPJL | down-regulates | SOX12 | activates | R-1115 | 18 | 5 | Drugs (13) Regulator Drugs (0)Regulon Drugs (13)CE-224535, TERODILINE, GSK1482160, E-6201, GABAPENTIN ENACARBIL, PREGABALIN, ATAGABALIN, GABAPENTIN, BEPRIDIL, SULOCTIDIL, IMAGABALIN, AZD9056, JNJ-54175446 |
| CMF-04199 | RBPJL | down-regulates | SOX12 | activates | R-1113 | 18 | 5 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-04202 | RBPJL | up-regulates | ATF3 | activates | R-469 | 5 | 3 | Drugs (11) Regulator Drugs (0)Regulon Drugs (11)BEVACIZUMAB, CONBERCEPT, PEGAPTANIB SODIUM, PEGAPTANIB OCTASODIUM, MUPARFOSTAT, VANUCIZUMAB, RANIBIZUMAB, FARICIMAB, ABICIPAR PEGOL, AFLIBERCEPT, BROLUCIZUMAB |
| CMF-04203 | RBPJL | up-regulates | ATF3 | activates | R-466 | 5 | 3 | Drugs (4) |
| CMF-04204 | RBPJL | up-regulates | SREBF1 | activates | R-2503 | 12 | 4 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-04205 | RBPJL | up-regulates | SREBF1 | activates | R-2500 | 12 | 4 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-04206 | RBPJL | up-regulates | SREBF1 | activates | R-2501 | 12 | 4 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-04207 | RBPJL | up-regulates | SREBF1 | activates | R-2498 | 12 | 4 | Drugs (5) |
| CMF-04209 | RBPJL | down-regulates | PAX1 | represses | R-254 | 3 | 2 | Drugs (29) Regulator Drugs (0)Regulon Drugs (29)RUPATADINE, CSL-324, DASATINIB, LIPEGFILGRASTIM, MEDI-2338, CAROTUXIMAB, BOSUTINIB, BAFETINIB, FILGRASTIM, BALUGRASTIM, ILORASERTIB, JNJ-26483327, TADEKINIG ALFA, PETESICATIB, NEIHULIZUMAB, XL-228, OTLERTUZUMAB, BI-836826, TOLIMIDONE, ERITORAN TETRASODIUM, TG100-801, LENOGRASTIM, OCRIPLASMIN, ERITORAN, PEGFILGRASTIM, NARATUXIMAB EMTANSINE, AMG-557, GSK-1070806, ENMD-981693 |
| CMF-04211 | RBPJL | down-regulates | THRA | represses | R-107 | 11 | 5 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-04212 | RBPJL | down-regulates | THRA | represses | R-99 | 11 | 5 | Drugs (5) |
| CMF-04213 | RBPJL | down-regulates | THRA | represses | R-97 | 11 | 5 | Drugs (59) Regulator Drugs (0)Regulon Drugs (59)PF-04691502, BGT-226, SONOLISIB, VOXTALISIB, BMS-986142, HM-71224, PICLIDENOSON, APITOLISIB, DS-7423, L19IL2, MSC-2364447, PAXALISIB, AS-1409, PICTILISIB, PF-06651600, ABIVERTINIB, ABIVERTINIB MALEATE, CAFFEINE, CITRATED, VS-5584, SAMOTOLISIB, L19TNFA, DACTOLISIB, GNF-Pf-5468, WX-037, RILZABRUTINIB, SPEBRUTINIB, PILARALISIB, TASELISIB, L19SIP 131I, IBRUTINIB, GEDATOLISIB, OMIPALISIB, ZANUBRUTINIB, EVOBRUTINIB, OTLERTUZUMAB, BI-836826, CAFFEINE, SPEBRUTINIB BESYLATE, POSELTINIB, ADENOSINE, PIRTOBRUTINIB, OCRIPLASMIN, ACALABRUTINIB, OXTRIPHYLLINE, ELSUBRUTINIB, BRANEBRUTINIB, NAMODENOSON, PA-799, TIRABRUTINIB, FENEBRUTINIB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, THEOPHYLLINE, SF-1126, ORELABRUTINIB, AMINOPHYLLINE, PANULISIB, NELFINAVIR |
| CMF-04218 | RBPJL | up-regulates | IRF1 | activates | R-118 | 25 | 10 | Drugs (7) |
| CMF-04219 | RBPJL | up-regulates | IRF1 | activates | R-114 | 25 | 10 | Drugs (10) |
| CMF-04220 | RBPJL | up-regulates | IRF1 | activates | R-123 | 25 | 10 | Drugs (1) |
| CMF-04222 | RBPJL | up-regulates | IRF1 | activates | R-133 | 25 | 10 | Drugs (42) Regulator Drugs (0)Regulon Drugs (42)EFATUTAZONE, FARGLITAZAR, SAROGLITAZAR, CHIGLITAZAR, PIOGLITAZONE HYDROCHLORIDE, OLSALAZINE, TROXACITABINE, CLOFARABINE, MURAGLITAZAR, BALAGLITAZONE, MK-0767, INT131, BEZAFIBRATE, TESAGLITAZAR, ROSIGLITAZONE MALEATE, CYTARABINE, DB959, GEMCITABINE HYDROCHLORIDE, ETALOCIB, OLSALAZINE SODIUM, MESALAMINE, ATX08-001, SODELGLITAZAR, GEMCITABINE, BALSALAZIDE DISODIUM, TROGLITAZONE, IMIGLITAZAR, MK-0533, ASPACYTARABINE, BARDOXOLONE METHYL, BALSALAZIDE, FLUDARABINE PHOSPHATE, LERIGLITAZONE, RIVOGLITAZONE, ARHALOFENATE, MBX-2044, PIOGLITAZONE, NAVEGLITAZAR, LANIFIBRANOR, INDEGLITAZAR, ROSIGLITAZONE, ALEGLITAZAR |
| CMF-04223 | RBPJL | up-regulates | IRF1 | activates | R-115 | 25 | 10 | Drugs (13) Regulator Drugs (0)Regulon Drugs (13)OPROZOMIB, INTERFERON GAMMA-1B, IXAZOMIB, MARIZOMIB, NIVOCASAN, BORTEZOMIB, EMRICASAN, EMAPUNIL, BELNACASAN, IXAZOMIB CITRATE, ALEMTUZUMAB, ONO-2952, CARFILZOMIB |
| CMF-04225 | RBPJL | up-regulates | IRF1 | activates | R-117 | 25 | 10 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL |
| CMF-04226 | RBPJL | down-regulates | FEV | represses | R-3034 | 5 | 2 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-04227 | RBPJL | down-regulates | FEV | represses | R-3032 | 5 | 2 | Drugs (18) Regulator Drugs (0)Regulon Drugs (18)FOSTAMATINIB DISODIUM, FIBOFLAPON SODIUM, R-343, AME-133V, R-348, CERDULATINIB, EFALIZUMAB, HMPL-523, ENTOSPLETINIB, R-333, GUSACITINIB, LIFITEGRAST, MIVAVOTINIB CITRATE, VELIFLAPON, FOSTAMATINIB, LANRAPLENIB, MIVAVOTINIB, FIBOFLAPON |
| CMF-04230 | RBPJL | down-regulates | MAZ | activates | R-607 | 25 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-04235 | RBPJL | down-regulates | LHX3 | represses | R-2011 | 24 | 11 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-04236 | RBPJL | down-regulates | LHX3 | represses | R-2015 | 24 | 11 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-04238 | RBPJL | down-regulates | LHX3 | represses | R-1999 | 24 | 11 | Drugs (84) Regulator Drugs (0)Regulon Drugs (84)IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, MELOXICAM, BROMFENAC SODIUM, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB |
| CMF-04242 | RBPJL | down-regulates | LHX3 | represses | R-2007 | 24 | 11 | Drugs (4) |
| CMF-04243 | RBPJL | down-regulates | LHX3 | represses | R-1997 | 24 | 11 | Drugs (33) Regulator Drugs (0)Regulon Drugs (33)SAVOLITINIB, TELISOTUZUMAB VEDOTIN, AMUVATINIB, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, MK-8033, AMG-337, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, JNJ-38877605, GLESATINIB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, GOLVATINIB |
| CMF-04246 | RBPJL | up-regulates | RUNX1 | activates | R-276 | 15 | 4 | Drugs (7) |
| CMF-04249 | RBPJL | down-regulates | POU3F1 | represses | R-1646 | 25 | 8 | Drugs (4) |
| CMF-04250 | RBPJL | down-regulates | POU3F1 | represses | R-1649 | 25 | 8 | Drugs (4) |
| CMF-04251 | RBPJL | down-regulates | POU3F1 | represses | R-1645 | 25 | 8 | Drugs (8) |
| CMF-04254 | RBPJL | down-regulates | POU3F1 | represses | R-1660 | 25 | 8 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-04255 | RBPJL | up-regulates | STAT5A | activates | R-2943 | 21 | 7 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL |
| CMF-04256 | RBPJL | up-regulates | STAT5A | activates | R-2946 | 21 | 7 | Drugs (76) Regulator Drugs (0)Regulon Drugs (76)IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, MELOXICAM, BROMFENAC SODIUM, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB |
| CMF-04257 | RBPJL | up-regulates | STAT5A | activates | R-2949 | 21 | 7 | Drugs (5) |
| CMF-04258 | RBPJL | up-regulates | STAT5A | activates | R-2953 | 21 | 7 | Drugs (4) |
| CMF-04259 | RBPJL | up-regulates | STAT5A | activates | R-2945 | 21 | 7 | Drugs (7) |
| CMF-04260 | RBPJL | up-regulates | STAT5A | activates | R-2955 | 21 | 7 | Drugs (1) |
| CMF-04262 | RBPJL | down-regulates | NEUROD1 | represses | R-3574 | 5 | 2 | Drugs (3) |
| CMF-04268 | RBPJL | up-regulates | PRRX1 | activates | R-3071 | 18 | 12 | Drugs (34) Regulator Drugs (0)Regulon Drugs (34)SAVOLITINIB, TELISOTUZUMAB VEDOTIN, AMUVATINIB, BIRINAPANT, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, MK-8033, AMG-337, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, JNJ-38877605, GLESATINIB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, GOLVATINIB |
| CMF-04269 | RBPJL | up-regulates | PRRX1 | activates | R-3073 | 18 | 12 | Drugs (3) |
| CMF-04271 | RBPJL | up-regulates | PRRX1 | activates | R-3072 | 18 | 12 | Drugs (2) |
| CMF-04275 | RBPJL | up-regulates | PRRX1 | activates | R-3080 | 18 | 12 | Drugs (2) |
| CMF-04276 | RBPJL | up-regulates | ARID5A | activates | R-171 | 15 | 3 | Drugs (2) |
| CMF-04277 | RBPJL | up-regulates | ARID5A | activates | R-160 | 15 | 3 | Drugs (2) |
| CMF-04278 | RBPJL | up-regulates | ARID5A | activates | R-165 | 15 | 3 | Drugs (5) |
| CMF-04281 | RBPJL | up-regulates | SP1 | represses | R-1370 | 8 | 2 | Drugs (120) Regulator Drugs (0)Regulon Drugs (120)ERIBULIN MESYLATE, SAGOPILONE, AGS-16C3F, TERODILINE, TELISOTUZUMAB VEDOTIN, ACAMPROSATE CALCIUM, DOCETAXEL, FOSBRETABULIN DISODIUM, CHF-6001, VINCRISTINE, VINFLUNINE, AV-101, LEXIBULIN, VINCRISTINE SULFATE, TRASTUZUMAB EMTANSINE, ENFORTUMAB VEDOTIN, MEMANTINE, VINORELBINE TARTRATE, LIFASTUZUMAB VEDOTIN, KOS-1584, APREMILAST, PRALUZATAMAB RAVTANSINE, DYPHYLLINE, OGLEMILAST, LADIRATUZUMAB VEDOTIN, MEMANTINE HYDROCHLORIDE, FLAVOXATE HYDROCHLORIDE, PACLITAXEL, ORPHENADRINE HYDROCHLORIDE, CROLIBULIN, MK-0873, TOFIMILAST, PACLITAXEL POLIGLUMEX, PATUPILONE, PENTOXIFYLLINE, ASG-5ME, ANG1005, DROTAVERINE, CEP-1347, PINATUZUMAB VEDOTIN, DIPYRIDAMOLE, VERUBULIN, VINBLASTINE SULFATE, VINORELBINE, DEFACTINIB, DAVUNETIDE, BELANTAMAB MAFODOTIN, FOSBRETABULIN, TRAXOPRODIL, NERAMEXANE, EVT-101, KETAMINE, IBUDILAST, MIRVETUXIMAB SORAVTANSINE, GSK-256066, ROFLUMILAST, IXABEPILONE, POLATUZUMAB VEDOTIN, ORPHENADRINE, T-900607, DIFAMILAST, APRUTUMAB IXADOTIN, PLINABULIN, GABAPENTIN ENACARBIL, TISOTUMAB VEDOTIN, DOLASTATIN-10, FOSBRETABULIN TROMETHAMINE, CILOMILAST, SAR-408701, FELBAMATE, CABAZITAXEL, FLAVOXATE, AMANTADINE HYDROCHLORIDE, PACLITAXEL DOCOSAHEXAENOIC ACID, PREGABALIN, RAPASTINEL, ATAGABALIN, GABAPENTIN, ERIBULIN, BMS-275183, INDUSATUMAB VEDOTIN, LANICEMINE, CRISABOROLE, RISLENEMDAZ, GLEMBATUMUMAB VEDOTIN, COLCHICINE, ACAMPROSATE, RALFINAMIDE, VANDORTUZUMAB VEDOTIN, VINBLASTINE, BEPRIDIL, BRENTUXIMAB VEDOTIN, SULOCTIDIL, GW468816, NERAMEXANE MESYLATE, IMAGABALIN, TETOMILAST, AMLEXANOX, EPOTHILONE D, SOFITUZUMAB VEDOTIN, INDIBULIN, ORPHENADRINE CITRATE, OXTRIPHYLLINE, RADIPRODIL, AZINTUXIZUMAB VEDOTIN, APIMOSTINEL, HT-0712, ESKETAMINE, INDANTADOL, LOTAMILAST, ESKETAMINE HYDROCHLORIDE, LAROTAXEL, RG-7841, AMANTADINE, CC-11050, LORVOTUZUMAB MERTANSINE, THEOPHYLLINE, KETAMINE HYDROCHLORIDE, AMINOPHYLLINE, CONTELTINIB |
| CMF-04282 | RBPJL | up-regulates | SP1 | represses | R-1373 | 8 | 2 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-04283 | RBPJL | up-regulates | YY1 | activates | R-62 | 25 | 2 | Drugs (3) |
| CMF-04286 | RBPJL | down-regulates | POU4F2 | represses | R-2784 | 13 | 3 | Drugs (9) |
| CMF-04287 | RBPJL | down-regulates | POU4F2 | represses | R-2790 | 13 | 3 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)ASK-8007 |
| CMF-04291 | RBPJL | down-regulates | E2F1 | activates | R-530 | 18 | 4 | Drugs (1) |
| CMF-04297 | RBPJL | down-regulates | MNX1 | represses | R-2262 | 4 | 1 | Drugs (59) Regulator Drugs (0)Regulon Drugs (59)IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN |
| CMF-04301 | RBPJL | down-regulates | GBX2 | represses | R-2078 | 7 | 2 | Drugs (7) |
| CMF-04303 | RBPJL | up-regulates | IRF8 | activates | R-411 | 18 | 6 | Drugs (2) |
| CMF-04304 | RBPJL | up-regulates | IRF8 | activates | R-406 | 18 | 6 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-04306 | RBPJL | up-regulates | IRF8 | activates | R-398 | 18 | 6 | Drugs (8) |
| CMF-04307 | RBPJL | up-regulates | IRF8 | activates | R-403 | 18 | 6 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-04308 | RBPJL | up-regulates | IRF8 | activates | R-397 | 18 | 6 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL |
| CMF-04309 | RBPJL | down-regulates | SOX11 | represses | R-848 | 19 | 5 | Drugs (7) |
| CMF-04315 | RBPJL | down-regulates | MYCN | represses | R-1806 | 5 | 2 | Drugs (2) |
| CMF-04318 | RBPJL | up-regulates | CEBPB | activates | R-1300 | 23 | 11 | Drugs (11) Regulator Drugs (0)Regulon Drugs (11)ATN-161, DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, NATALIZUMAB, FIRATEGRAST, EMRICASAN, VOLOCIXIMAB, RECOMBINANT HUMAN INTERLEUKIN-15, PEGINTERFERON LAMBDA-1A, ABITUZUMAB |
| CMF-04320 | RBPJL | up-regulates | CEBPB | activates | R-1309 | 23 | 11 | Drugs (6) |
| CMF-04321 | RBPJL | up-regulates | CEBPB | activates | R-1304 | 23 | 11 | Drugs (6) |
| CMF-04322 | RBPJL | up-regulates | CEBPB | activates | R-1321 | 23 | 11 | Drugs (1) |
| CMF-04326 | RBPJL | up-regulates | CEBPB | activates | R-1314 | 23 | 11 | Drugs (1) |
| CMF-04327 | RBPJL | up-regulates | CEBPB | activates | R-1317 | 23 | 11 | Drugs (58) Regulator Drugs (0)Regulon Drugs (58)ERIBULIN MESYLATE, SAGOPILONE, AGS-16C3F, TELISOTUZUMAB VEDOTIN, DOCETAXEL, FOSBRETABULIN DISODIUM, VINCRISTINE, VINFLUNINE, LEXIBULIN, VINCRISTINE SULFATE, TRASTUZUMAB EMTANSINE, ENFORTUMAB VEDOTIN, VINORELBINE TARTRATE, LIFASTUZUMAB VEDOTIN, KOS-1584, PRALUZATAMAB RAVTANSINE, LADIRATUZUMAB VEDOTIN, PACLITAXEL, CROLIBULIN, PACLITAXEL POLIGLUMEX, PATUPILONE, ASG-5ME, ANG1005, PINATUZUMAB VEDOTIN, VERUBULIN, VINBLASTINE SULFATE, VINORELBINE, DAVUNETIDE, BELANTAMAB MAFODOTIN, FOSBRETABULIN, ABT-751, MIRVETUXIMAB SORAVTANSINE, IXABEPILONE, POLATUZUMAB VEDOTIN, T-900607, APRUTUMAB IXADOTIN, PLINABULIN, TISOTUMAB VEDOTIN, DOLASTATIN-10, FOSBRETABULIN TROMETHAMINE, SAR-408701, CABAZITAXEL, PACLITAXEL DOCOSAHEXAENOIC ACID, ERIBULIN, BMS-275183, INDUSATUMAB VEDOTIN, GLEMBATUMUMAB VEDOTIN, COLCHICINE, VANDORTUZUMAB VEDOTIN, VINBLASTINE, BRENTUXIMAB VEDOTIN, EPOTHILONE D, SOFITUZUMAB VEDOTIN, INDIBULIN, AZINTUXIZUMAB VEDOTIN, LAROTAXEL, RG-7841, LORVOTUZUMAB MERTANSINE |
| CMF-04336 | RBPJL | down-regulates | SOX3 | represses | R-1732 | 6 | 5 | Drugs (59) Regulator Drugs (0)Regulon Drugs (59)IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN |
| CMF-04337 | RBPJL | down-regulates | SOX3 | represses | R-1730 | 6 | 5 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-04338 | RBPJL | down-regulates | SOX3 | represses | R-1731 | 6 | 5 | Drugs (2) |
| CMF-04339 | RBPJL | down-regulates | TRAF4 | represses | R-2271 | 14 | 2 | Drugs (2) |
| CMF-04342 | RBPJL | down-regulates | POU6F2 | represses | R-2612 | 12 | 4 | Drugs (2) |
| CMF-04344 | RBPJL | down-regulates | POU6F2 | represses | R-2609 | 12 | 4 | Drugs (2) |
| CMF-04350 | RBPJL | down-regulates | DLX2 | represses | R-3577 | 4 | 2 | Drugs (7) |
| CMF-04352 | RBPJL | down-regulates | TCF7L1 | represses | R-449 | 9 | 2 | Drugs (1) |
| CMF-04353 | RBPJL | down-regulates | TCF7L1 | represses | R-445 | 9 | 2 | Drugs (7) |
| CMF-04354 | RBPJL | down-regulates | NR0B1 | represses | R-2533 | 3 | 1 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-34529 | RBPJL | down-regulates | hsa-mir-328 | represses | R-257 | 27 | 9 | Drugs (149) Regulator Drugs (0)Regulon Drugs (149)PF-04691502, FOSTAMATINIB DISODIUM, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, FIBOFLAPON SODIUM, BGT-226, SONOLISIB, RUPATADINE, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, INTERFERON GAMMA-1B, ONERCEPT, R-343, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, ABATACEPT, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, CCR5MAB004, R-348, AMY-101, PEGSUNERCEPT, GOLIMUMAB, VICRIVIROC, CAFFEINE, CITRATED, MEDI-2338, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, AVE-9633, VOBARILIZUMAB, CERDULATINIB, VESATOLIMOD, DUVELISIB, L19TNFA, APLAVIROC, MARAVIROC, AZD-8848, DACTOLISIB, BOSUTINIB, BAFETINIB, ZANDELISIB, HMPL-523, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, LERONLIMAB, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, TASELISIB, JNJ-26483327, L19SIP 131I, AMG-319, UCN-01, TADEKINIG ALFA, HYDROXYCHLOROQUINE SULFATE, HGS-1025, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, NEIHULIZUMAB, GEMTUZUMAB, CENICRIVIROC, IDELALISIB, APLAVIROC HYDROCHLORIDE, BELATACEPT, XL-228, FIMEPINOSTAT, ENTOSPLETINIB, SATRALIZUMAB, CPG-52852, SELGANTOLIMOD, R-333, IMIQUIMOD, GUSACITINIB, REMTOLUMAB, TOLIMIDONE, CAFFEINE, MOTOLIMOD, TOMIVOSERTIB, BMS-813160, GEMTUZUMAB OZOGAMICIN, PF-04634817, TG100-801, INCB-9471, PEGCETACOPLAN, VICRIVIROC MALEATE, ADENOSINE, DUPILUMAB, ACALISIB, PF-232798, GSK-2245035, MIVAVOTINIB CITRATE, VELIFLAPON, TELRATOLIMOD, AZD5672, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, MILATUZUMAB, FOSTAMATINIB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, LINTUZUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, LANRAPLENIB, MIVAVOTINIB, BUPARLISIB, VESENCUMAB, GSK-690693, THEOPHYLLINE, SF-1126, AMINOPHYLLINE, GSK-1070806, FIBOFLAPON, AL-78898A, ENMD-981693, PANULISIB |
| CMF-34530 | RBPJL | down-regulates | hsa-mir-328 | represses | R-157 | 27 | 9 | Drugs (5) |
| CMF-34531 | RBPJL | down-regulates | hsa-mir-328 | represses | R-2601 | 27 | 9 | Drugs (5) |
| CMF-34532 | RBPJL | down-regulates | hsa-mir-328 | represses | R-2765 | 27 | 9 | Drugs (5) |
| CMF-34533 | RBPJL | down-regulates | hsa-mir-328 | represses | R-2781 | 27 | 9 | Drugs (5) |
| CMF-34534 | RBPJL | down-regulates | hsa-mir-328 | represses | R-2945 | 27 | 9 | Drugs (7) |
| CMF-34535 | RBPJL | down-regulates | hsa-mir-328 | represses | R-3029 | 27 | 9 | Drugs (5) |
| CMF-34536 | RBPJL | down-regulates | hsa-mir-328 | represses | R-3131 | 27 | 9 | Drugs (5) |
| CMF-34537 | RBPJL | down-regulates | hsa-mir-328 | represses | R-1895 | 27 | 9 | Drugs (5) |
| CMF-34538 | RBPJL | down-regulates | hsa-mir-363 | represses | R-189 | 19 | 11 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-34539 | RBPJL | down-regulates | hsa-mir-363 | represses | R-274 | 19 | 11 | Drugs (2) |
| CMF-34540 | RBPJL | down-regulates | hsa-mir-363 | represses | R-307 | 19 | 11 | Drugs (2) |
| CMF-34541 | RBPJL | down-regulates | hsa-mir-363 | represses | R-411 | 19 | 11 | Drugs (2) |
| CMF-34542 | RBPJL | down-regulates | hsa-mir-363 | represses | R-2489 | 19 | 11 | Drugs (2) |
| CMF-34543 | RBPJL | down-regulates | hsa-mir-363 | represses | R-2605 | 19 | 11 | Drugs (2) |
| CMF-34544 | RBPJL | down-regulates | hsa-mir-363 | represses | R-3028 | 19 | 11 | Drugs (2) |
| CMF-34545 | RBPJL | down-regulates | hsa-mir-363 | represses | R-1091 | 19 | 11 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-34546 | RBPJL | down-regulates | hsa-mir-363 | represses | R-1457 | 19 | 11 | Drugs (2) |
| CMF-34547 | RBPJL | down-regulates | hsa-mir-363 | represses | R-3695 | 19 | 11 | Drugs (2) |
| CMF-34548 | RBPJL | down-regulates | hsa-mir-363 | represses | R-1847 | 19 | 11 | Drugs (2) |