Mutation

List of causal flows influenced by the mutation.

Causal Flows are statistically significant links between putative causal events (somatic mutations, copy number variations, chromosomal translocations, etc.) and the activity levels of regulators and regulons. In the causal flow, a mutation may causally activate or deactivate a downstream regulator which then might up- down-regulates a regulon that contains genes with similar expression profiles and binding sites.

Causal Mechanistic Flows regulated by Mutation MCM6_code_potential_somatic

ID	Mutation	Role	Regulator	Role	Regulon	# downstream regulons	# diffexp regulons	Drugs
CMF-01593	MCM6	down-regulates	FGF9	represses	R-1770	4	1	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-01594	MCM6	up-regulates	SP100	activates	R-2585	3	1	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-01595	MCM6	down-regulates	SATB1	activates	R-1693	24	3	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-01596	MCM6	down-regulates	SATB1	represses	R-1679	24	3	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-01597	MCM6	down-regulates	SATB1	represses	R-1676	24	3	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) DAVANAT, NIVOCASAN, EMRICASAN, PEGINTERFERON LAMBDA-1A
CMF-01599	MCM6	down-regulates	FOXL1	represses	R-1853	25	2	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-01600	MCM6	up-regulates	MAFB	activates	R-1912	25	7	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) ALEPLASININ, COLLAGENASE CLOSTRIDIUM HISTOLYTICUM, OCRIPLASMIN, VESENCUMAB
CMF-01601	MCM6	up-regulates	MAFB	activates	R-1901	25	7	Drugs (44) Regulator Drugs (0) Regulon Drugs (44) SAVOLITINIB, TELISOTUZUMAB VEDOTIN, ATN-161, AMUVATINIB, BIRINAPANT, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, CILENGITIDE, TIROFIBAN HYDROCHLORIDE, MK-8033, AMG-337, ABCIXIMAB, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, ETARACIZUMAB, JNJ-38877605, GLESATINIB, INTETUMUMAB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, NEDOSIRAN SODIUM, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, EPTIFIBATIDE, ABITUZUMAB, GOLVATINIB, TIROFIBAN
CMF-01602	MCM6	up-regulates	MAFB	activates	R-1905	25	7	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) DINOPROSTONE, CR-6086, GRAPIPRANT, RIVENPROST, DIQUAFOSOL, DIQUAFOSOL TETRASODIUM
CMF-01603	MCM6	up-regulates	MAFB	activates	R-1902	25	7	Drugs (29) Regulator Drugs (0) Regulon Drugs (29) FOSTAMATINIB DISODIUM, FIBOFLAPON SODIUM, HYDROXYCHLOROQUINE, R-343, AME-133V, R-348, CERDULATINIB, VESATOLIMOD, AZD-8848, EFALIZUMAB, HMPL-523, HYDROXYCHLOROQUINE SULFATE, PETESICATIB, ENTOSPLETINIB, CPG-52852, R-333, IMIQUIMOD, IC14, GUSACITINIB, LIFITEGRAST, VB-201, GSK-2245035, MIVAVOTINIB CITRATE, VELIFLAPON, TELRATOLIMOD, FOSTAMATINIB, LANRAPLENIB, MIVAVOTINIB, FIBOFLAPON
CMF-01604	MCM6	up-regulates	MAFB	activates	R-1911	25	7	Drugs (23) Regulator Drugs (0) Regulon Drugs (23) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-01605	MCM6	up-regulates	MAFB	activates	R-1903	25	7	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-01607	MCM6	down-regulates	ALX4	represses	R-2926	20	1	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-01608	MCM6	up-regulates	ATF5	activates	R-362	14	6	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) DICHLORPHENAMIDE, SULTHIAME, ACETAZOLAMIDE, OCRIPLASMIN, ACETAZOLAMIDE SODIUM, VESENCUMAB
CMF-01609	MCM6	up-regulates	ATF5	activates	R-359	14	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) EMRICASAN
CMF-01610	MCM6	up-regulates	ATF5	activates	R-358	14	6	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) BRODALUMAB, DIQUAFOSOL, DIQUAFOSOL TETRASODIUM
CMF-01611	MCM6	up-regulates	ATF5	activates	R-357	14	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) DAVANAT
CMF-01612	MCM6	up-regulates	ATF5	activates	R-356	14	6	Drugs (108) Regulator Drugs (0) Regulon Drugs (108) PF-04691502, UMBRALISIB, FIBOFLAPON SODIUM, BGT-226, SONOLISIB, CSL-324, HYDROXYCHLOROQUINE, PARSACLISIB, INTERFERON GAMMA-1B, VOXTALISIB, BMS-986142, HM-71224, NEMIRALISIB, RP-6530, APITOLISIB, AME-133V, DS-7423, GSK-2269557, L19IL2, INCB-40093, MSC-2364447, PAXALISIB, AS-1409, PICTILISIB, PF-06651600, AMY-101, LIPEGFILGRASTIM, ABIVERTINIB, VRC-01LS, ABIVERTINIB MALEATE, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, EFALIZUMAB, DACTOLISIB, FILGRASTIM, ZANDELISIB, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, RILZABRUTINIB, BALUGRASTIM, SPEBRUTINIB, PILARALISIB, TASELISIB, L19SIP 131I, AMG-319, IBRUTINIB, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, ZANUBRUTINIB, FIMEPINOSTAT, SATRALIZUMAB, EVOBRUTINIB, CPG-52852, IMIQUIMOD, IC14, TREGALIZUMAB, ERITORAN TETRASODIUM, SPEBRUTINIB BESYLATE, PEGCETACOPLAN, LENOGRASTIM, POSELTINIB, LIFITEGRAST, VB-201, ACALISIB, ZANOLIMUMAB, GSK-2245035, VELIFLAPON, PIRTOBRUTINIB, TELRATOLIMOD, IBALIZUMAB, OCRIPLASMIN, CAL-263, UB-421, ACALABRUTINIB, ERITORAN, ELSUBRUTINIB, BRANEBRUTINIB, LENIOLISIB, PA-799, TIRABRUTINIB, FENEBRUTINIB, LEVILIMAB, GSK-1059615, PEGFILGRASTIM, BUPARLISIB, VESENCUMAB, SF-1126, ORELABRUTINIB, FIBOFLAPON, AL-78898A, PANULISIB
CMF-01613	MCM6	up-regulates	ATF5	activates	R-367	14	6	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) OBATOCLAX MESYLATE, OBATOCLAX, HCBE-11
CMF-01614	MCM6	down-regulates	SIX6	represses	R-3173	4	2	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) ATN-161, CINTREDEKIN BESUDOTOX, NIVOCASAN, NATALIZUMAB, FIRATEGRAST, EMRICASAN, VOLOCIXIMAB, ABITUZUMAB
CMF-01615	MCM6	down-regulates	SIX6	represses	R-3175	4	2	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) TOSEDOSTAT
CMF-01617	MCM6	down-regulates	LHX3	represses	R-1995	24	6	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) DINOPROSTONE, CR-6086, GRAPIPRANT, RIVENPROST, DIQUAFOSOL, DIQUAFOSOL TETRASODIUM
CMF-01618	MCM6	down-regulates	LHX3	represses	R-2008	24	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) MARIMASTAT
CMF-01619	MCM6	down-regulates	LHX3	represses	R-2005	24	6	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) COLLAGENASE CLOSTRIDIUM HISTOLYTICUM, OCRIPLASMIN, VESENCUMAB
CMF-01621	MCM6	down-regulates	LHX3	represses	R-2007	24	6	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) NANGIBOTIDE, CARLUMAB, ENILURACIL, GIMERACIL
CMF-01623	MCM6	up-regulates	IKZF1	activates	R-3137	16	6	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) BI-505, OBATOCLAX MESYLATE, OBATOCLAX, HCBE-11, AVDORALIMAB, AVACOPAN, ALICAFORSEN
CMF-01624	MCM6	up-regulates	IKZF1	activates	R-3133	16	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) CINTREDEKIN BESUDOTOX
CMF-01625	MCM6	up-regulates	IKZF1	activates	R-3135	16	6	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) DIQUAFOSOL, DIQUAFOSOL TETRASODIUM
CMF-01626	MCM6	up-regulates	IKZF1	activates	R-3134	16	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BRENSOCATIB
CMF-01627	MCM6	up-regulates	IKZF1	activates	R-3138	16	6	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) L19IL2, AS-1409, L19TNFA, L19SIP 131I, OCRIPLASMIN
CMF-01629	MCM6	down-regulates	TEF	represses	R-2659	15	1	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BENFLUOREX, NEVANIMIBE
CMF-01630	MCM6	down-regulates	THRB	represses	R-438	6	2	Drugs (27) Regulator Drugs (3) RESMETIROM, MB07811, EPROTIROME Regulon Drugs (24) LY-2787106, PICOTAMIDE, FIBOFLAPON SODIUM, ATN-161, TERBOGREL, L19IL2, AS-1409, L19TNFA, MUPARFOSTAT, PREXIGEBERSEN, L19SIP 131I, PF-04605412, OTLERTUZUMAB, BI-836826, ERITORAN TETRASODIUM, VELIFLAPON, OCRIPLASMIN, ERITORAN, MILATUZUMAB, VOLOCIXIMAB, OZAGREL, VESENCUMAB, NARATUXIMAB EMTANSINE, FIBOFLAPON
CMF-01631	MCM6	down-regulates	THRB	represses	R-440	6	2	Drugs (4) Regulator Drugs (3) RESMETIROM, MB07811, EPROTIROME Regulon Drugs (1) BIVATUZUMAB
CMF-01632	MCM6	down-regulates	MNX1	represses	R-2262	4	1	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-01633	MCM6	up-regulates	STAT6	activates	R-2279	11	3	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) DIQUAFOSOL, DIQUAFOSOL TETRASODIUM
CMF-01635	MCM6	up-regulates	STAT6	activates	R-2287	11	3	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) CELGOSIVIR, DUVOGLUSTAT, DUVOGLUSTAT HYDROCHLORIDE, AT-13148, MIGLITOL, VOGLIBOSE
CMF-01636	MCM6	down-regulates	HOXD13	represses	R-3758	1	1	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) EDASALONEXENT, L19IL2, AS-1409, L19TNFA, L19SIP 131I, COLLAGENASE CLOSTRIDIUM HISTOLYTICUM, OCRIPLASMIN
CMF-01637	MCM6	up-regulates	MAFF	activates	R-3371	2	2	Drugs (6) Regulator Drugs (0) Regulon Drugs (6) FIBOFLAPON SODIUM, AME-133V, EFALIZUMAB, LIFITEGRAST, VELIFLAPON, FIBOFLAPON
CMF-01638	MCM6	up-regulates	MAFF	activates	R-3370	2	2	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-33948	MCM6	down-regulates	hsa-mir-139	represses	R-2053	58	34	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) DICHLORPHENAMIDE, ALEPLASININ, SULTHIAME, ACETAZOLAMIDE, COLLAGENASE CLOSTRIDIUM HISTOLYTICUM, OCRIPLASMIN, TOSEDOSTAT, ACETAZOLAMIDE SODIUM, VESENCUMAB
CMF-33949	MCM6	down-regulates	hsa-mir-139	represses	R-117	58	34	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-33950	MCM6	down-regulates	hsa-mir-139	represses	R-152	58	34	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) MARIMASTAT
CMF-33951	MCM6	down-regulates	hsa-mir-139	represses	R-171	58	34	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-33952	MCM6	down-regulates	hsa-mir-139	represses	R-2326	58	34	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) MARIMASTAT
CMF-33953	MCM6	down-regulates	hsa-mir-139	represses	R-307	58	34	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-33954	MCM6	down-regulates	hsa-mir-139	represses	R-2402	58	34	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-33955	MCM6	down-regulates	hsa-mir-139	represses	R-2412	58	34	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-33956	MCM6	down-regulates	hsa-mir-139	represses	R-378	58	34	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) DINOPROSTONE, BRODALUMAB, CR-6086, GRAPIPRANT, RIVENPROST, DIQUAFOSOL, DIQUAFOSOL TETRASODIUM
CMF-33957	MCM6	down-regulates	hsa-mir-139	represses	R-397	58	34	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-33958	MCM6	down-regulates	hsa-mir-139	represses	R-2446	58	34	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-33959	MCM6	down-regulates	hsa-mir-139	represses	R-419	58	34	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BRENSOCATIB, EMRICASAN
CMF-33960	MCM6	down-regulates	hsa-mir-139	represses	R-2477	58	34	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BRENSOCATIB, EMRICASAN
CMF-33961	MCM6	down-regulates	hsa-mir-139	represses	R-2489	58	34	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-33962	MCM6	down-regulates	hsa-mir-139	represses	R-2585	58	34	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-33963	MCM6	down-regulates	hsa-mir-139	represses	R-572	58	34	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-33964	MCM6	down-regulates	hsa-mir-139	represses	R-646	58	34	Drugs (15) Regulator Drugs (0) Regulon Drugs (15) ALEPLASININ, SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, COLLAGENASE CLOSTRIDIUM HISTOLYTICUM, OCRIPLASMIN, TOSEDOSTAT, BHQ-880, VESENCUMAB, ABITUZUMAB
CMF-33965	MCM6	down-regulates	hsa-mir-139	represses	R-737	58	34	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-33966	MCM6	down-regulates	hsa-mir-139	represses	R-2837	58	34	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-33967	MCM6	down-regulates	hsa-mir-139	represses	R-2885	58	34	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BRENSOCATIB
CMF-33968	MCM6	down-regulates	hsa-mir-139	represses	R-3010	58	34	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-33969	MCM6	down-regulates	hsa-mir-139	represses	R-3028	58	34	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-33970	MCM6	down-regulates	hsa-mir-139	represses	R-998	58	34	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) DINOPROSTONE, BRODALUMAB, CR-6086, GRAPIPRANT, RIVENPROST
CMF-33971	MCM6	down-regulates	hsa-mir-139	represses	R-1006	58	34	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) MERIMEPODIB, MYCOPHENOLATE MOFETIL, MIZORIBINE, AVN-944, MYCOPHENOLIC ACID, MARIMASTAT, THIOGUANINE, RIBAVIRIN
CMF-33972	MCM6	down-regulates	hsa-mir-139	represses	R-3134	58	34	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BRENSOCATIB
CMF-33973	MCM6	down-regulates	hsa-mir-139	represses	R-1091	58	34	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-33974	MCM6	down-regulates	hsa-mir-139	represses	R-3348	58	34	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) EMRICASAN
CMF-33975	MCM6	down-regulates	hsa-mir-139	represses	R-1312	58	34	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) IMSIDOLIMAB, SPESOLIMAB
CMF-33976	MCM6	down-regulates	hsa-mir-139	represses	R-1457	58	34	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-33977	MCM6	down-regulates	hsa-mir-139	represses	R-1592	58	34	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-33978	MCM6	down-regulates	hsa-mir-139	represses	R-3695	58	34	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-33979	MCM6	down-regulates	hsa-mir-139	represses	R-1829	58	34	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BRENSOCATIB, EMRICASAN
CMF-33980	MCM6	down-regulates	hsa-mir-139	represses	R-2008	58	34	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) MARIMASTAT
CMF-33981	MCM6	down-regulates	hsa-mir-139	represses	R-2043	58	34	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) MERIMEPODIB, MYCOPHENOLATE MOFETIL, MIZORIBINE, AVN-944, MYCOPHENOLIC ACID, MARIMASTAT, THIOGUANINE, RIBAVIRIN
CMF-33982	MCM6	down-regulates	hsa-mir-129	represses	R-2053	155	76	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) DICHLORPHENAMIDE, ALEPLASININ, SULTHIAME, ACETAZOLAMIDE, COLLAGENASE CLOSTRIDIUM HISTOLYTICUM, OCRIPLASMIN, TOSEDOSTAT, ACETAZOLAMIDE SODIUM, VESENCUMAB
CMF-33983	MCM6	down-regulates	hsa-mir-129	represses	R-2104	155	76	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-33984	MCM6	down-regulates	hsa-mir-129	represses	R-61	155	76	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) PROBUCOL
CMF-33985	MCM6	down-regulates	hsa-mir-129	represses	R-2123	155	76	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BRENSOCATIB
CMF-33986	MCM6	down-regulates	hsa-mir-129	represses	R-2145	155	76	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-33987	MCM6	down-regulates	hsa-mir-129	represses	R-113	155	76	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) TAS0612, LANATOSIDE C, CEP-1347, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-33988	MCM6	down-regulates	hsa-mir-129	represses	R-2161	155	76	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BRENSOCATIB, EMRICASAN
CMF-33989	MCM6	down-regulates	hsa-mir-129	represses	R-117	155	76	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-33990	MCM6	down-regulates	hsa-mir-129	represses	R-152	155	76	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) MARIMASTAT
CMF-33991	MCM6	down-regulates	hsa-mir-129	represses	R-177	155	76	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-33992	MCM6	down-regulates	hsa-mir-129	represses	R-227	155	76	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) MERIMEPODIB, MYCOPHENOLATE MOFETIL, MIZORIBINE, AVN-944, MYCOPHENOLIC ACID, MARIMASTAT, THIOGUANINE, TOSEDOSTAT, RIBAVIRIN
CMF-33993	MCM6	down-regulates	hsa-mir-129	represses	R-2326	155	76	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) MARIMASTAT
CMF-33994	MCM6	down-regulates	hsa-mir-129	represses	R-307	155	76	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-33995	MCM6	down-regulates	hsa-mir-129	represses	R-2402	155	76	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-33996	MCM6	down-regulates	hsa-mir-129	represses	R-2412	155	76	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-33997	MCM6	down-regulates	hsa-mir-129	represses	R-377	155	76	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-33998	MCM6	down-regulates	hsa-mir-129	represses	R-2426	155	76	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) ATN-161, TAS0612, LANATOSIDE C, NIVOCASAN, NATALIZUMAB, FIRATEGRAST, EMRICASAN, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, VOLOCIXIMAB, RECOMBINANT HUMAN INTERLEUKIN-15, DESLANOSIDE, ISTAROXIME, ABITUZUMAB
CMF-33999	MCM6	down-regulates	hsa-mir-129	represses	R-2431	155	76	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) ANG1005, PROBUCOL
CMF-34000	MCM6	down-regulates	hsa-mir-129	represses	R-2441	155	76	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) MARIMASTAT, TOSEDOSTAT
CMF-34001	MCM6	down-regulates	hsa-mir-129	represses	R-397	155	76	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-34002	MCM6	down-regulates	hsa-mir-129	represses	R-2446	155	76	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-34003	MCM6	down-regulates	hsa-mir-129	represses	R-2451	155	76	Drugs (14) Regulator Drugs (0) Regulon Drugs (14) TAS0612, DASATINIB, LANATOSIDE C, VANDETANIB, TESEVATINIB, DIGOXIN, JI-101, ACETYLDIGITOXIN, TG100-801, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, REGORAFENIB, ISTAROXIME
CMF-34004	MCM6	down-regulates	hsa-mir-129	represses	R-415	155	76	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34005	MCM6	down-regulates	hsa-mir-129	represses	R-419	155	76	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BRENSOCATIB, EMRICASAN
CMF-34006	MCM6	down-regulates	hsa-mir-129	represses	R-2477	155	76	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BRENSOCATIB, EMRICASAN
CMF-34007	MCM6	down-regulates	hsa-mir-129	represses	R-2489	155	76	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-34008	MCM6	down-regulates	hsa-mir-129	represses	R-2500	155	76	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-34009	MCM6	down-regulates	hsa-mir-129	represses	R-2585	155	76	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-34010	MCM6	down-regulates	hsa-mir-129	represses	R-572	155	76	Drugs (11) Regulator Drugs (0) Regulon Drugs (11) SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, BHQ-880, ABITUZUMAB
CMF-34011	MCM6	down-regulates	hsa-mir-129	represses	R-2622	155	76	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34012	MCM6	down-regulates	hsa-mir-129	represses	R-576	155	76	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34013	MCM6	down-regulates	hsa-mir-129	represses	R-626	155	76	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34014	MCM6	down-regulates	hsa-mir-129	represses	R-646	155	76	Drugs (15) Regulator Drugs (0) Regulon Drugs (15) ALEPLASININ, SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, COLLAGENASE CLOSTRIDIUM HISTOLYTICUM, OCRIPLASMIN, TOSEDOSTAT, BHQ-880, VESENCUMAB, ABITUZUMAB
CMF-34015	MCM6	down-regulates	hsa-mir-129	represses	R-651	155	76	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) ANG1005, PROBUCOL
CMF-34016	MCM6	down-regulates	hsa-mir-129	represses	R-679	155	76	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34017	MCM6	down-regulates	hsa-mir-129	represses	R-2767	155	76	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-34018	MCM6	down-regulates	hsa-mir-129	represses	R-737	155	76	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-34019	MCM6	down-regulates	hsa-mir-129	represses	R-738	155	76	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34020	MCM6	down-regulates	hsa-mir-129	represses	R-2798	155	76	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-34021	MCM6	down-regulates	hsa-mir-129	represses	R-2830	155	76	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) ANG1005, PROBUCOL
CMF-34022	MCM6	down-regulates	hsa-mir-129	represses	R-2837	155	76	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-34023	MCM6	down-regulates	hsa-mir-129	represses	R-2864	155	76	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) ANG1005, PROBUCOL
CMF-34024	MCM6	down-regulates	hsa-mir-129	represses	R-2883	155	76	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34025	MCM6	down-regulates	hsa-mir-129	represses	R-2885	155	76	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BRENSOCATIB
CMF-34026	MCM6	down-regulates	hsa-mir-129	represses	R-2940	155	76	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) TAS0612, OCRIPLASMIN
CMF-34027	MCM6	down-regulates	hsa-mir-129	represses	R-2972	155	76	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-34028	MCM6	down-regulates	hsa-mir-129	represses	R-3010	155	76	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) SULTHIAME, CILENGITIDE, SENICAPOC, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, TOSEDOSTAT, ABITUZUMAB
CMF-34029	MCM6	down-regulates	hsa-mir-129	represses	R-3013	155	76	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34030	MCM6	down-regulates	hsa-mir-129	represses	R-970	155	76	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34031	MCM6	down-regulates	hsa-mir-129	represses	R-3028	155	76	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-34032	MCM6	down-regulates	hsa-mir-129	represses	R-3031	155	76	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) TAS0612, OCRIPLASMIN
CMF-34033	MCM6	down-regulates	hsa-mir-129	represses	R-3033	155	76	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-34034	MCM6	down-regulates	hsa-mir-129	represses	R-995	155	76	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34035	MCM6	down-regulates	hsa-mir-129	represses	R-1006	155	76	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) MERIMEPODIB, MYCOPHENOLATE MOFETIL, MIZORIBINE, AVN-944, MYCOPHENOLIC ACID, MARIMASTAT, THIOGUANINE, RIBAVIRIN
CMF-34036	MCM6	down-regulates	hsa-mir-129	represses	R-3061	155	76	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-34037	MCM6	down-regulates	hsa-mir-129	represses	R-1047	155	76	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) MERIMEPODIB, MYCOPHENOLATE MOFETIL, MIZORIBINE, AVN-944, MYCOPHENOLIC ACID, MARIMASTAT, THIOGUANINE, TOSEDOSTAT, RIBAVIRIN
CMF-34038	MCM6	down-regulates	hsa-mir-129	represses	R-1067	155	76	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34039	MCM6	down-regulates	hsa-mir-129	represses	R-3134	155	76	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BRENSOCATIB
CMF-34040	MCM6	down-regulates	hsa-mir-129	represses	R-1091	155	76	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-34041	MCM6	down-regulates	hsa-mir-129	represses	R-3180	155	76	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) ANG1005
CMF-34042	MCM6	down-regulates	hsa-mir-129	represses	R-3231	155	76	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34043	MCM6	down-regulates	hsa-mir-129	represses	R-3348	155	76	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) EMRICASAN
CMF-34044	MCM6	down-regulates	hsa-mir-129	represses	R-3449	155	76	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34045	MCM6	down-regulates	hsa-mir-129	represses	R-3459	155	76	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34046	MCM6	down-regulates	hsa-mir-129	represses	R-3481	155	76	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) TAS0612, ANG1005, PROBUCOL, OCRIPLASMIN
CMF-34047	MCM6	down-regulates	hsa-mir-129	represses	R-1457	155	76	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-34048	MCM6	down-regulates	hsa-mir-129	represses	R-1592	155	76	Drugs (17) Regulator Drugs (0) Regulon Drugs (17) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-34049	MCM6	down-regulates	hsa-mir-129	represses	R-1645	155	76	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34050	MCM6	down-regulates	hsa-mir-129	represses	R-3695	155	76	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) NI-0801, ELDELUMAB
CMF-34051	MCM6	down-regulates	hsa-mir-129	represses	R-1679	155	76	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-34052	MCM6	down-regulates	hsa-mir-129	represses	R-1829	155	76	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) BRENSOCATIB, EMRICASAN
CMF-34053	MCM6	down-regulates	hsa-mir-129	represses	R-1853	155	76	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34054	MCM6	down-regulates	hsa-mir-129	represses	R-1890	155	76	Drugs (9) Regulator Drugs (0) Regulon Drugs (9) MERIMEPODIB, MYCOPHENOLATE MOFETIL, MIZORIBINE, AVN-944, MYCOPHENOLIC ACID, MARIMASTAT, THIOGUANINE, TOSEDOSTAT, RIBAVIRIN
CMF-34055	MCM6	down-regulates	hsa-mir-129	represses	R-1926	155	76	Drugs (15) Regulator Drugs (0) Regulon Drugs (15) CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, ELDECALCITOL, CALCIPOTRIENE, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL
CMF-34056	MCM6	down-regulates	hsa-mir-129	represses	R-2008	155	76	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) MARIMASTAT
CMF-34057	MCM6	down-regulates	hsa-mir-129	represses	R-2043	155	76	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) MERIMEPODIB, MYCOPHENOLATE MOFETIL, MIZORIBINE, AVN-944, MYCOPHENOLIC ACID, MARIMASTAT, THIOGUANINE, RIBAVIRIN

Causal Mechanistic Flows regulated by Mutation MCM6_code_potential_somatic

Regulator Drugs (0)

Regulon Drugs (1)

Regulator Drugs (0)

Regulon Drugs (0)

Regulator Drugs (0)

Regulon Drugs (0)

Regulator Drugs (0)

Regulon Drugs (0)

Regulator Drugs (0)

Regulon Drugs (4)

Regulator Drugs (0)

Regulon Drugs (8)

Regulator Drugs (0)

Regulon Drugs (4)

Regulator Drugs (0)

Regulon Drugs (44)

Regulator Drugs (0)

Regulon Drugs (6)

Regulator Drugs (0)

Regulon Drugs (29)

Regulator Drugs (0)

Regulon Drugs (23)

Regulator Drugs (0)

Regulon Drugs (8)

Regulator Drugs (0)

Regulon Drugs (0)

Regulator Drugs (0)

Regulon Drugs (6)

Regulator Drugs (0)

Regulon Drugs (1)

Regulator Drugs (0)

Regulon Drugs (3)

Regulator Drugs (0)

Regulon Drugs (1)

Regulator Drugs (0)

Regulon Drugs (108)

Regulator Drugs (0)

Regulon Drugs (3)

Regulator Drugs (0)

Regulon Drugs (8)

Regulator Drugs (0)

Regulon Drugs (1)

Regulator Drugs (0)

Regulon Drugs (6)

Regulator Drugs (0)

Regulon Drugs (1)

Regulator Drugs (0)

Regulon Drugs (3)

Regulator Drugs (0)

Regulon Drugs (4)

Regulator Drugs (0)

Regulon Drugs (7)

Regulator Drugs (0)

Regulon Drugs (1)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (1)

Regulator Drugs (0)

Regulon Drugs (5)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (3)

Regulon Drugs (24)

Regulator Drugs (3)

Regulon Drugs (1)

Regulator Drugs (0)

Regulon Drugs (59)

Regulator Drugs (0)

Regulon Drugs (2)

Regulator Drugs (0)

Regulon Drugs (6)

Regulator Drugs (0)

Regulon Drugs (7)

Regulator Drugs (0)

Regulon Drugs (6)

Regulator Drugs (0)

Regulon Drugs (0)