| CMF-21506 | KLHL34 | down-regulates | MAFB | activates | R-1901 | 25 | 4 | Drugs (44) Regulator Drugs (0)Regulon Drugs (44)SAVOLITINIB, TELISOTUZUMAB VEDOTIN, ATN-161, AMUVATINIB, BIRINAPANT, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, CILENGITIDE, TIROFIBAN HYDROCHLORIDE, MK-8033, AMG-337, ABCIXIMAB, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, ETARACIZUMAB, JNJ-38877605, GLESATINIB, INTETUMUMAB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, NEDOSIRAN SODIUM, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, EPTIFIBATIDE, ABITUZUMAB, GOLVATINIB, TIROFIBAN |
| CMF-21507 | KLHL34 | down-regulates | MAFB | activates | R-1905 | 25 | 4 | Drugs (6) |
| CMF-21508 | KLHL34 | down-regulates | MAFB | activates | R-1903 | 25 | 4 | Drugs (8) |
| CMF-21509 | KLHL34 | down-regulates | MAFB | activates | R-1916 | 25 | 4 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |
| CMF-21511 | KLHL34 | down-regulates | RORA | activates | R-1945 | 8 | 2 | Drugs (7) |
| CMF-21512 | KLHL34 | down-regulates | RORA | activates | R-1949 | 8 | 2 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-21513 | KLHL34 | up-regulates | POU4F1 | represses | R-2763 | 11 | 1 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)ASK-8007 |
| CMF-21514 | KLHL34 | up-regulates | FEV | represses | R-3030 | 5 | 3 | Drugs (71) Regulator Drugs (0)Regulon Drugs (71)ESTROGENS, ESTERIFIED, SAVOLITINIB, TELISOTUZUMAB VEDOTIN, ATN-161, RALOXIFENE, PRINABEREL, LASOFOXIFENE, AMUVATINIB, BAZEDOXIFENE ACETATE, CHLOROTRIANISENE, ESTRIOL, BIRINAPANT, ACOLBIFENE, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, SYNTHETIC CONJUGATED ESTROGENS, B, OSPEMIFENE, TEPOTINIB HYDROCHLORIDE, TOREMIFENE CITRATE, FORETINIB, RALOXIFENE HYDROCHLORIDE, ONARTUZUMAB, SAR-125844, ERTEBEREL, AMG-208, FULVESTRANT, CILENGITIDE, TIROFIBAN HYDROCHLORIDE, ESTROGENS, CONJUGATED SYNTHETIC A, ESTROGENS, CONJUGATED, MK-8033, FISPEMIFENE, AMG-337, ABCIXIMAB, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, AFIMOXIFENE, MK-2461, MERESTINIB, DIETHYLSTILBESTROL DIPHOSPHATE, BMS-777607, BAZEDOXIFENE, CAPMATINIB, ETARACIZUMAB, JNJ-38877605, GLESATINIB, INTETUMUMAB, BMS-817378, CABOZANTINIB S-MALATE, MF101, AUS-131, CRIZOTINIB, TOREMIFENE, EMD-1204831, TIVANTINIB, ESTRAMUSTINE PHOSPHATE, NEDOSIRAN SODIUM, TELISOTUZUMAB, ESTETROL, TEPOTINIB, EMIBETUZUMAB, BPI-9016, ESTRAMUSTINE PHOSPHATE SODIUM, PF-04217903, ARZOXIFENE, EPTIFIBATIDE, ABITUZUMAB, GOLVATINIB, TIROFIBAN |
| CMF-21515 | KLHL34 | up-regulates | FEV | represses | R-3034 | 5 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-21516 | KLHL34 | up-regulates | FEV | represses | R-3031 | 5 | 3 | Drugs (2) |
| CMF-21518 | KLHL34 | down-regulates | NR1H3 | activates | R-3091 | 4 | 1 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-21520 | KLHL34 | down-regulates | PRRX1 | activates | R-3071 | 18 | 2 | Drugs (34) Regulator Drugs (0)Regulon Drugs (34)SAVOLITINIB, TELISOTUZUMAB VEDOTIN, AMUVATINIB, BIRINAPANT, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, MK-8033, AMG-337, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, JNJ-38877605, GLESATINIB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, GOLVATINIB |
| CMF-21521 | KLHL34 | down-regulates | PRRX1 | activates | R-3072 | 18 | 2 | Drugs (2) |
| CMF-21524 | KLHL34 | down-regulates | GATA6 | activates | R-1258 | 18 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-21525 | KLHL34 | down-regulates | IRF3 | activates | R-2426 | 25 | 4 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)ATN-161, TAS0612, LANATOSIDE C, NIVOCASAN, NATALIZUMAB, FIRATEGRAST, EMRICASAN, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, VOLOCIXIMAB, RECOMBINANT HUMAN INTERLEUKIN-15, DESLANOSIDE, ISTAROXIME, ABITUZUMAB |
| CMF-21531 | KLHL34 | down-regulates | ELF4 | activates | R-3010 | 20 | 6 | Drugs (9) |
| CMF-21532 | KLHL34 | down-regulates | ELF4 | activates | R-3024 | 20 | 6 | Drugs (12) Regulator Drugs (0)Regulon Drugs (12)INTERFERON BETA-1B, ANIFROLUMAB, INTERFERON ALFA-2A, INTERFERON ALFA-2B, PEGINTERFERON ALFA-2B, INTERFERON ALFA-N3, ALBINTERFERON ALFA-2B, INTERFERON ALFACON-1, ROPEGINTERFERON ALFA-2B, PEGINTERFERON ALFA-2A, PEGINTERFERON BETA-1A, INTERFERON BETA-1A |
| CMF-21533 | KLHL34 | down-regulates | ELF4 | activates | R-3013 | 20 | 6 | Drugs (8) |
| CMF-21534 | KLHL34 | down-regulates | ELF4 | activates | R-3012 | 20 | 6 | Drugs (70) Regulator Drugs (0)Regulon Drugs (70)ESTROGENS, ESTERIFIED, SAVOLITINIB, TELISOTUZUMAB VEDOTIN, ATN-161, RALOXIFENE, PRINABEREL, LASOFOXIFENE, AMUVATINIB, BAZEDOXIFENE ACETATE, CHLOROTRIANISENE, ESTRIOL, BIRINAPANT, ACOLBIFENE, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, SYNTHETIC CONJUGATED ESTROGENS, B, OSPEMIFENE, TEPOTINIB HYDROCHLORIDE, TOREMIFENE CITRATE, FORETINIB, RALOXIFENE HYDROCHLORIDE, ONARTUZUMAB, SAR-125844, ERTEBEREL, AMG-208, FULVESTRANT, CILENGITIDE, TIROFIBAN HYDROCHLORIDE, ESTROGENS, CONJUGATED SYNTHETIC A, ESTROGENS, CONJUGATED, MK-8033, FISPEMIFENE, AMG-337, ABCIXIMAB, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, AFIMOXIFENE, MK-2461, MERESTINIB, DIETHYLSTILBESTROL DIPHOSPHATE, BMS-777607, BAZEDOXIFENE, CAPMATINIB, ETARACIZUMAB, JNJ-38877605, GLESATINIB, INTETUMUMAB, BMS-817378, CABOZANTINIB S-MALATE, MF101, AUS-131, CRIZOTINIB, TOREMIFENE, EMD-1204831, TIVANTINIB, ESTRAMUSTINE PHOSPHATE, TELISOTUZUMAB, ESTETROL, TEPOTINIB, EMIBETUZUMAB, BPI-9016, ESTRAMUSTINE PHOSPHATE SODIUM, PF-04217903, ARZOXIFENE, EPTIFIBATIDE, ABITUZUMAB, GOLVATINIB, TIROFIBAN |
| CMF-21537 | KLHL34 | up-regulates | MYCN | represses | R-1806 | 5 | 1 | Drugs (2) |
| CMF-21538 | KLHL34 | down-regulates | ELF3 | activates | R-3686 | 14 | 2 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-21541 | KLHL34 | down-regulates | STAT1 | activates | R-2468 | 21 | 6 | Drugs (12) Regulator Drugs (0)Regulon Drugs (12)INTERFERON BETA-1B, ANIFROLUMAB, INTERFERON ALFA-2A, INTERFERON ALFA-2B, PEGINTERFERON ALFA-2B, INTERFERON ALFA-N3, ALBINTERFERON ALFA-2B, INTERFERON ALFACON-1, ROPEGINTERFERON ALFA-2B, PEGINTERFERON ALFA-2A, PEGINTERFERON BETA-1A, INTERFERON BETA-1A |
| CMF-21542 | KLHL34 | down-regulates | STAT1 | activates | R-2464 | 21 | 6 | Drugs (1) |
| CMF-21543 | KLHL34 | down-regulates | STAT1 | activates | R-2465 | 21 | 6 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |
| CMF-21544 | KLHL34 | down-regulates | STAT1 | activates | R-2451 | 21 | 6 | Drugs (14) Regulator Drugs (0)Regulon Drugs (14)TAS0612, DASATINIB, LANATOSIDE C, VANDETANIB, TESEVATINIB, DIGOXIN, JI-101, ACETYLDIGITOXIN, TG100-801, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, REGORAFENIB, ISTAROXIME |
| CMF-21545 | KLHL34 | down-regulates | STAT1 | activates | R-2469 | 21 | 6 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)APATORSEN |