| CMF-21295 | GRIK3 | up-regulates | GABPA | activates | R-38 | 8 | 4 | Drugs (3) |
| CMF-21297 | GRIK3 | up-regulates | IRF2 | activates | R-415 | 25 | 9 | Drugs (8) |
| CMF-21299 | GRIK3 | up-regulates | IRF2 | activates | R-426 | 25 | 9 | Drugs (11) Regulator Drugs (0)Regulon Drugs (11)AMG-780, MEDI-3617, ENIBARCIMAB, F16SIP 131I, TREBANANIB, F16IL2, VANUCIZUMAB, PROBUCOL, FARICIMAB, CVX-060, NESVACUMAB |
| CMF-21303 | GRIK3 | up-regulates | IRF2 | activates | R-416 | 25 | 9 | Drugs (10) |
| CMF-21304 | GRIK3 | up-regulates | IRF2 | activates | R-424 | 25 | 9 | Drugs (4) |
| CMF-21308 | GRIK3 | up-regulates | NFKB1 | activates | R-297 | 25 | 5 | Drugs (6) |
| CMF-21312 | GRIK3 | up-regulates | NFKB1 | activates | R-292 | 25 | 5 | Drugs (20) Regulator Drugs (0)Regulon Drugs (20)GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN |
| CMF-21314 | GRIK3 | up-regulates | HMGA1 | activates | R-1071 | 16 | 4 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-21317 | GRIK3 | up-regulates | HMGA1 | activates | R-1067 | 16 | 4 | Drugs (7) |
| CMF-21318 | GRIK3 | up-regulates | NR3C1 | activates | R-2031 | 21 | 6 | Drugs (102) Regulator Drugs (0)Regulon Drugs (102)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, GSK-1995057, RUPATADINE, DOXYLAMINE SUCCINATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, DICHLORPHENAMIDE, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, EBASTINE, SULTHIAME, CINNARIZINE, HYDROXYZINE, LORATADINE, EPELSIBAN, LY2624803, PHENIRAMINE MALEATE, ACETAZOLAMIDE, TRIPROLIDINE HYDROCHLORIDE, OXYTOCIN, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, CARBETOCIN, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, TISOTUMAB VEDOTIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, NOLASIBAN, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, VANTICTUMAB, BROMODIPHENHYDRAMINE, ATOSIBAN, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, FE 202767, MIZOLASTINE, HYDROXYZINE PAMOATE, BARUSIBAN, ALCAFTADINE, ACETAZOLAMIDE SODIUM, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, CETIRIZINE, RETOSIBAN, METHDILAZINE |
| CMF-21321 | GRIK3 | up-regulates | NR3C1 | activates | R-2032 | 21 | 6 | Drugs (90) Regulator Drugs (0)Regulon Drugs (90)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, RUPATADINE, DOXYLAMINE SUCCINATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, IMSIDOLIMAB, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, EBASTINE, CINNARIZINE, HYDROXYZINE, LORATADINE, LY2624803, BELZUTIFAN, PHENIRAMINE MALEATE, TRIPROLIDINE HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, CETIRIZINE, SPESOLIMAB, METHDILAZINE |
| CMF-21323 | GRIK3 | up-regulates | NR3C1 | activates | R-2047 | 21 | 6 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-21329 | GRIK3 | down-regulates | LMX1B | represses | R-2927 | 11 | 3 | Drugs (1) |
| CMF-21331 | GRIK3 | down-regulates | SOX10 | represses | R-3063 | 8 | 3 | Drugs (33) Regulator Drugs (0)Regulon Drugs (33)SAVOLITINIB, TELISOTUZUMAB VEDOTIN, AMUVATINIB, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, MK-8033, AMG-337, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, JNJ-38877605, GLESATINIB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, GOLVATINIB |
| CMF-21333 | GRIK3 | down-regulates | SOX10 | represses | R-3069 | 8 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-21334 | GRIK3 | down-regulates | POU4F1 | represses | R-2756 | 11 | 2 | Drugs (2) |
| CMF-21335 | GRIK3 | down-regulates | POU4F1 | represses | R-2760 | 11 | 2 | Drugs (3) |
| CMF-21339 | GRIK3 | up-regulates | IRF1 | activates | R-121 | 25 | 7 | Drugs (20) Regulator Drugs (0)Regulon Drugs (20)BEVACIZUMAB, CONBERCEPT, AMG-780, MEDI-3617, PEGAPTANIB SODIUM, ENIBARCIMAB, F16SIP 131I, TREBANANIB, PEGAPTANIB OCTASODIUM, MUPARFOSTAT, F16IL2, VANUCIZUMAB, PROBUCOL, RANIBIZUMAB, FARICIMAB, CVX-060, ABICIPAR PEGOL, NESVACUMAB, AFLIBERCEPT, BROLUCIZUMAB |
| CMF-21340 | GRIK3 | up-regulates | IRF1 | activates | R-123 | 25 | 7 | Drugs (1) |
| CMF-21342 | GRIK3 | up-regulates | IRF1 | activates | R-115 | 25 | 7 | Drugs (13) Regulator Drugs (0)Regulon Drugs (13)OPROZOMIB, INTERFERON GAMMA-1B, IXAZOMIB, MARIZOMIB, NIVOCASAN, BORTEZOMIB, EMRICASAN, EMAPUNIL, BELNACASAN, IXAZOMIB CITRATE, ALEMTUZUMAB, ONO-2952, CARFILZOMIB |
| CMF-21343 | GRIK3 | down-regulates | FEV | represses | R-3030 | 5 | 2 | Drugs (71) Regulator Drugs (0)Regulon Drugs (71)ESTROGENS, ESTERIFIED, SAVOLITINIB, TELISOTUZUMAB VEDOTIN, ATN-161, RALOXIFENE, PRINABEREL, LASOFOXIFENE, AMUVATINIB, BAZEDOXIFENE ACETATE, CHLOROTRIANISENE, ESTRIOL, BIRINAPANT, ACOLBIFENE, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, SYNTHETIC CONJUGATED ESTROGENS, B, OSPEMIFENE, TEPOTINIB HYDROCHLORIDE, TOREMIFENE CITRATE, FORETINIB, RALOXIFENE HYDROCHLORIDE, ONARTUZUMAB, SAR-125844, ERTEBEREL, AMG-208, FULVESTRANT, CILENGITIDE, TIROFIBAN HYDROCHLORIDE, ESTROGENS, CONJUGATED SYNTHETIC A, ESTROGENS, CONJUGATED, MK-8033, FISPEMIFENE, AMG-337, ABCIXIMAB, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, AFIMOXIFENE, MK-2461, MERESTINIB, DIETHYLSTILBESTROL DIPHOSPHATE, BMS-777607, BAZEDOXIFENE, CAPMATINIB, ETARACIZUMAB, JNJ-38877605, GLESATINIB, INTETUMUMAB, BMS-817378, CABOZANTINIB S-MALATE, MF101, AUS-131, CRIZOTINIB, TOREMIFENE, EMD-1204831, TIVANTINIB, ESTRAMUSTINE PHOSPHATE, NEDOSIRAN SODIUM, TELISOTUZUMAB, ESTETROL, TEPOTINIB, EMIBETUZUMAB, BPI-9016, ESTRAMUSTINE PHOSPHATE SODIUM, PF-04217903, ARZOXIFENE, EPTIFIBATIDE, ABITUZUMAB, GOLVATINIB, TIROFIBAN |
| CMF-21344 | GRIK3 | down-regulates | FEV | represses | R-3031 | 5 | 2 | Drugs (2) |
| CMF-21345 | GRIK3 | down-regulates | SIX6 | represses | R-3174 | 4 | 2 | Drugs (3) |
| CMF-21346 | GRIK3 | down-regulates | SIX6 | represses | R-3176 | 4 | 2 | Drugs (4) |
| CMF-21347 | GRIK3 | up-regulates | DR1 | activates | R-2981 | 8 | 4 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)DIAZOXIDE |
| CMF-21348 | GRIK3 | up-regulates | DR1 | activates | R-2987 | 8 | 4 | Drugs (4) |
| CMF-21353 | GRIK3 | up-regulates | TGIF1 | activates | R-1400 | 9 | 3 | Drugs (4) |
| CMF-21355 | GRIK3 | up-regulates | MEOX2 | activates | R-2203 | 14 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-21356 | GRIK3 | up-regulates | MEOX2 | activates | R-2202 | 14 | 3 | Drugs (5) |
| CMF-21357 | GRIK3 | up-regulates | NR1H3 | activates | R-3093 | 4 | 1 | Drugs (59) Regulator Drugs (0)Regulon Drugs (59)IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN |
| CMF-21359 | GRIK3 | down-regulates | HOXD9 | represses | R-1671 | 5 | 2 | Drugs (1) |
| CMF-21360 | GRIK3 | down-regulates | PAX7 | represses | R-3698 | 3 | 1 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-21361 | GRIK3 | up-regulates | FOSL1 | activates | R-1993 | 12 | 7 | Drugs (58) Regulator Drugs (0)Regulon Drugs (58)ERIBULIN MESYLATE, SAGOPILONE, AGS-16C3F, TELISOTUZUMAB VEDOTIN, DOCETAXEL, FOSBRETABULIN DISODIUM, VINCRISTINE, VINFLUNINE, LEXIBULIN, VINCRISTINE SULFATE, TRASTUZUMAB EMTANSINE, ENFORTUMAB VEDOTIN, VINORELBINE TARTRATE, LIFASTUZUMAB VEDOTIN, KOS-1584, PRALUZATAMAB RAVTANSINE, LADIRATUZUMAB VEDOTIN, PACLITAXEL, CROLIBULIN, PACLITAXEL POLIGLUMEX, PATUPILONE, ASG-5ME, ANG1005, PINATUZUMAB VEDOTIN, VERUBULIN, VINBLASTINE SULFATE, VINORELBINE, DAVUNETIDE, BELANTAMAB MAFODOTIN, FOSBRETABULIN, ABT-751, MIRVETUXIMAB SORAVTANSINE, IXABEPILONE, POLATUZUMAB VEDOTIN, T-900607, APRUTUMAB IXADOTIN, PLINABULIN, TISOTUMAB VEDOTIN, DOLASTATIN-10, FOSBRETABULIN TROMETHAMINE, SAR-408701, CABAZITAXEL, PACLITAXEL DOCOSAHEXAENOIC ACID, ERIBULIN, BMS-275183, INDUSATUMAB VEDOTIN, GLEMBATUMUMAB VEDOTIN, COLCHICINE, VANDORTUZUMAB VEDOTIN, VINBLASTINE, BRENTUXIMAB VEDOTIN, EPOTHILONE D, SOFITUZUMAB VEDOTIN, INDIBULIN, AZINTUXIZUMAB VEDOTIN, LAROTAXEL, RG-7841, LORVOTUZUMAB MERTANSINE |
| CMF-21362 | GRIK3 | up-regulates | FOSL1 | activates | R-1983 | 12 | 7 | Drugs (94) Regulator Drugs (0)Regulon Drugs (94)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, GSK-1995057, RUPATADINE, DOXYLAMINE SUCCINATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, DICHLORPHENAMIDE, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, EBASTINE, SULTHIAME, CINNARIZINE, HYDROXYZINE, LORATADINE, LY2624803, PHENIRAMINE MALEATE, ACETAZOLAMIDE, TRIPROLIDINE HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, TISOTUMAB VEDOTIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, VANTICTUMAB, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, ACETAZOLAMIDE SODIUM, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, CETIRIZINE, METHDILAZINE |
| CMF-21363 | GRIK3 | up-regulates | FOSL1 | activates | R-1982 | 12 | 7 | Drugs (3) |
| CMF-21365 | GRIK3 | up-regulates | FOSL1 | activates | R-1992 | 12 | 7 | Drugs (3) |
| CMF-21368 | GRIK3 | down-regulates | NEUROD1 | represses | R-3572 | 5 | 1 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-21370 | GRIK3 | down-regulates | HOXB13 | represses | R-3231 | 15 | 4 | Drugs (7) |
| CMF-21375 | GRIK3 | up-regulates | CEBPZ | activates | R-2995 | 12 | 4 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)TAS0612 |
| CMF-21377 | GRIK3 | up-regulates | CEBPZ | activates | R-2994 | 12 | 4 | Drugs (33) Regulator Drugs (0)Regulon Drugs (33)SAVOLITINIB, TELISOTUZUMAB VEDOTIN, AMUVATINIB, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, MK-8033, AMG-337, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, JNJ-38877605, GLESATINIB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, GOLVATINIB |
| CMF-21378 | GRIK3 | down-regulates | BARX2 | represses | R-1753 | 7 | 1 | Drugs (2) |
| CMF-21383 | GRIK3 | down-regulates | TLX2 | represses | R-1568 | 25 | 5 | Drugs (3) |
| CMF-21385 | GRIK3 | down-regulates | POU4F2 | represses | R-2783 | 13 | 7 | Drugs (7) |
| CMF-21390 | GRIK3 | down-regulates | POU4F2 | represses | R-2782 | 13 | 7 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-21397 | GRIK3 | up-regulates | PRDM4 | activates | R-2086 | 8 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-21400 | GRIK3 | down-regulates | HSF4 | represses | R-2798 | 4 | 2 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-21401 | GRIK3 | down-regulates | HSF4 | represses | R-2797 | 4 | 2 | Drugs (1) |
| CMF-21404 | GRIK3 | down-regulates | MNX1 | activates | R-2261 | 4 | 1 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-21405 | GRIK3 | down-regulates | HOXC8 | represses | R-2231 | 2 | 1 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)ASK-8007 |
| CMF-21406 | GRIK3 | down-regulates | PAX2 | represses | R-1183 | 4 | 1 | Drugs (97) Regulator Drugs (0)Regulon Drugs (97)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, RUPATADINE, DOXYLAMINE SUCCINATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, EBASTINE, CINNARIZINE, HYDROXYZINE, LORATADINE, EPELSIBAN, LY2624803, PHENIRAMINE MALEATE, TRIPROLIDINE HYDROCHLORIDE, OXYTOCIN, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, CARBETOCIN, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, TISOTUMAB VEDOTIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, NOLASIBAN, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, VANTICTUMAB, BROMODIPHENHYDRAMINE, ATOSIBAN, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, FE 202767, MIZOLASTINE, HYDROXYZINE PAMOATE, BARUSIBAN, ALCAFTADINE, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, CETIRIZINE, RETOSIBAN, METHDILAZINE |
| CMF-21411 | GRIK3 | down-regulates | VSX1 | represses | R-2356 | 16 | 4 | Drugs (33) Regulator Drugs (0)Regulon Drugs (33)SAVOLITINIB, TELISOTUZUMAB VEDOTIN, AMUVATINIB, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, MK-8033, AMG-337, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, JNJ-38877605, GLESATINIB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, GOLVATINIB |
| CMF-21413 | GRIK3 | up-regulates | ZNF282 | activates | R-1205 | 4 | 1 | Drugs (112) Regulator Drugs (0)Regulon Drugs (112)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PAZOPANIB, PYRILAMINE MALEATE, TRIPELENNAMINE, RUPATADINE, DOXYLAMINE SUCCINATE, PEMIGATINIB, BRIVANIB ALANINATE, MECLIZINE, ERDAFITINIB, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, HMPL-453, CHLORPHENIRAMINE MALEATE, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, PAZOPANIB HYDROCHLORIDE, LEVOCABASTINE, BRIVANIB, DEXBROMPHENIRAMINE MALEATE, EBASTINE, NINTEDANIB ESYLATE, CINNARIZINE, ABX-464, HYDROXYZINE, LORATADINE, LY2624803, PHENIRAMINE MALEATE, TRIPROLIDINE HYDROCHLORIDE, XL-999, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, DOVITINIB, ROGARATINIB, BUCLIZINE, EPINASTINE, AZD-4547, ORPHENADRINE, ENMD-2076, KETOTIFEN, FEXOFENADINE, BILASTINE, INFIGRATINIB, FGFR INHIBITOR DEBIO 1347, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, PROMETHAZINE, INFIGRATINIB PHOSPHATE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, NINTEDANIB, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, FUTIBATINIB, MASITINIB, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, ORANTINIB, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, OCRIPLASMIN, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, DERAZANTINIB, E-7090, HYDROXYZINE PAMOATE, ALCAFTADINE, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, CETIRIZINE, ENMD-981693, METHDILAZINE |
| CMF-21416 | GRIK3 | down-regulates | HOXA11 | represses | R-2737 | 5 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-21418 | GRIK3 | up-regulates | CEBPB | activates | R-1304 | 23 | 7 | Drugs (6) |
| CMF-21419 | GRIK3 | up-regulates | CEBPB | activates | R-1321 | 23 | 7 | Drugs (1) |
| CMF-21421 | GRIK3 | up-regulates | CEBPB | activates | R-1301 | 23 | 7 | Drugs (91) Regulator Drugs (0)Regulon Drugs (91)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, RUPATADINE, DOXYLAMINE SUCCINATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, IMSIDOLIMAB, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, EBASTINE, CINNARIZINE, HYDROXYZINE, LORATADINE, LY2624803, BELZUTIFAN, PHENIRAMINE MALEATE, TRIPROLIDINE HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, OCRIPLASMIN, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, CETIRIZINE, SPESOLIMAB, METHDILAZINE |
| CMF-21422 | GRIK3 | up-regulates | CEBPB | activates | R-1306 | 23 | 7 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)ANG1005 |
| CMF-21423 | GRIK3 | up-regulates | CEBPB | activates | R-1317 | 23 | 7 | Drugs (58) Regulator Drugs (0)Regulon Drugs (58)ERIBULIN MESYLATE, SAGOPILONE, AGS-16C3F, TELISOTUZUMAB VEDOTIN, DOCETAXEL, FOSBRETABULIN DISODIUM, VINCRISTINE, VINFLUNINE, LEXIBULIN, VINCRISTINE SULFATE, TRASTUZUMAB EMTANSINE, ENFORTUMAB VEDOTIN, VINORELBINE TARTRATE, LIFASTUZUMAB VEDOTIN, KOS-1584, PRALUZATAMAB RAVTANSINE, LADIRATUZUMAB VEDOTIN, PACLITAXEL, CROLIBULIN, PACLITAXEL POLIGLUMEX, PATUPILONE, ASG-5ME, ANG1005, PINATUZUMAB VEDOTIN, VERUBULIN, VINBLASTINE SULFATE, VINORELBINE, DAVUNETIDE, BELANTAMAB MAFODOTIN, FOSBRETABULIN, ABT-751, MIRVETUXIMAB SORAVTANSINE, IXABEPILONE, POLATUZUMAB VEDOTIN, T-900607, APRUTUMAB IXADOTIN, PLINABULIN, TISOTUMAB VEDOTIN, DOLASTATIN-10, FOSBRETABULIN TROMETHAMINE, SAR-408701, CABAZITAXEL, PACLITAXEL DOCOSAHEXAENOIC ACID, ERIBULIN, BMS-275183, INDUSATUMAB VEDOTIN, GLEMBATUMUMAB VEDOTIN, COLCHICINE, VANDORTUZUMAB VEDOTIN, VINBLASTINE, BRENTUXIMAB VEDOTIN, EPOTHILONE D, SOFITUZUMAB VEDOTIN, INDIBULIN, AZINTUXIZUMAB VEDOTIN, LAROTAXEL, RG-7841, LORVOTUZUMAB MERTANSINE |
| CMF-21428 | GRIK3 | down-regulates | PAX5 | represses | R-352 | 6 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-21429 | GRIK3 | up-regulates | ATF1 | activates | R-457 | 7 | 1 | Drugs (1) |
| CMF-21430 | GRIK3 | up-regulates | SMAD1 | activates | R-1484 | 21 | 4 | Drugs (41) Regulator Drugs (0)Regulon Drugs (41)POZIOTINIB, MM-111, TRASTUZUMAB DERUXTECAN, VARLITINIB, CUDC-101, LAPATINIB DITOSYLATE, TUCATINIB, HEMAY-022, MP-412, TRASTUZUMAB EMTANSINE, ZENOCUTUZUMAB, CANERTINIB DIHYDROCHLORIDE, NERATINIB MALEATE, MUBRITINIB, LAPATINIB, SAPITINIB, NERATINIB, BMS-690514, AC-480, DACOMITINIB, KBP5209, TARLOXOTINIB, VANDETANIB, ALLITINIB, ERTUMAXOMAB, TRASTUZUMAB DUOCARMAZINE, MARGETUXIMAB, TRASTUZUMAB, T-DM1, CANERTINIB, BDTX189, JNJ-26483327, TESEVATINIB, AFATINIB DIMALEATE, CP-724714, AFATINIB, AEE-788, PYROTINIB, TAK-285, PERTUZUMAB, GANCOTAMAB |
| CMF-40284 | GRIK3 | down-regulates | hsa-mir-330 | represses | R-2532 | 15 | 5 | Drugs (8) |
| CMF-40285 | GRIK3 | down-regulates | hsa-mir-330 | represses | R-2760 | 15 | 5 | Drugs (3) |
| CMF-40286 | GRIK3 | down-regulates | hsa-mir-330 | represses | R-2950 | 15 | 5 | Drugs (3) |
| CMF-40287 | GRIK3 | down-regulates | hsa-mir-330 | represses | R-1546 | 15 | 5 | Drugs (1) |
| CMF-40288 | GRIK3 | down-regulates | hsa-mir-330 | represses | R-3643 | 15 | 5 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-40289 | GRIK3 | down-regulates | hsa-mir-30b | represses | R-189 | 9 | 5 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-40290 | GRIK3 | down-regulates | hsa-mir-30b | represses | R-274 | 9 | 5 | Drugs (2) |
| CMF-40291 | GRIK3 | down-regulates | hsa-mir-30b | represses | R-411 | 9 | 5 | Drugs (2) |
| CMF-40292 | GRIK3 | down-regulates | hsa-mir-30b | represses | R-2605 | 9 | 5 | Drugs (2) |
| CMF-40293 | GRIK3 | down-regulates | hsa-mir-30b | represses | R-1847 | 9 | 5 | Drugs (2) |