| CMF-26679 | FBN2 | down-regulates | NKX2-8 | represses | R-670 | 12 | 2 | Drugs (17) Regulator Drugs (0)Regulon Drugs (17)BEVACIZUMAB, CONBERCEPT, AMG-780, MEDI-3617, PEGAPTANIB SODIUM, ENIBARCIMAB, TREBANANIB, PEGAPTANIB OCTASODIUM, MUPARFOSTAT, VANUCIZUMAB, RANIBIZUMAB, FARICIMAB, CVX-060, ABICIPAR PEGOL, NESVACUMAB, AFLIBERCEPT, BROLUCIZUMAB |
| CMF-26681 | FBN2 | down-regulates | FGF9 | represses | R-1770 | 4 | 1 | Drugs (1) |
| CMF-26682 | FBN2 | down-regulates | LHX1 | represses | R-2963 | 17 | 2 | Drugs (34) Regulator Drugs (0)Regulon Drugs (34)SAVOLITINIB, TELISOTUZUMAB VEDOTIN, AMUVATINIB, BIRINAPANT, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, MK-8033, AMG-337, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, JNJ-38877605, GLESATINIB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, GOLVATINIB |
| CMF-26685 | FBN2 | down-regulates | FOXD3 | represses | R-576 | 25 | 4 | Drugs (8) |
| CMF-26687 | FBN2 | down-regulates | FOXD3 | represses | R-575 | 25 | 4 | Drugs (6) |
| CMF-26689 | FBN2 | down-regulates | POU4F1 | represses | R-2756 | 11 | 1 | Drugs (2) |
| CMF-26692 | FBN2 | up-regulates | TEAD3 | activates | R-2104 | 15 | 2 | Drugs (7) |
| CMF-26694 | FBN2 | down-regulates | POU4F2 | represses | R-2783 | 13 | 6 | Drugs (7) |
| CMF-26699 | FBN2 | up-regulates | FOXF2 | activates | R-2289 | 10 | 2 | Drugs (9) |
| CMF-26706 | FBN2 | down-regulates | ELF3 | represses | R-3683 | 14 | 1 | Drugs (20) Regulator Drugs (0)Regulon Drugs (20)BEVACIZUMAB, CONBERCEPT, AMG-780, MEDI-3617, PEGAPTANIB SODIUM, ENIBARCIMAB, F16SIP 131I, TREBANANIB, PEGAPTANIB OCTASODIUM, MUPARFOSTAT, F16IL2, VANUCIZUMAB, PROBUCOL, RANIBIZUMAB, FARICIMAB, CVX-060, ABICIPAR PEGOL, NESVACUMAB, AFLIBERCEPT, BROLUCIZUMAB |
| CMF-26707 | FBN2 | down-regulates | E2F3 | activates | R-496 | 6 | 1 | Drugs (64) Regulator Drugs (0)Regulon Drugs (64)CE-224535, ROPIVACAINE, MORICIZINE, PHENYTOIN, QUINIDINE POLYGALACTURONATE, FOSPHENYTOIN SODIUM, CHLOROPROCAINE HYDROCHLORIDE, ENCAINIDE, GSK1482160, ESLICARBAZEPINE, PROCAINAMIDE HYDROCHLORIDE, PRALUZATAMAB RAVTANSINE, MEPHENYTOIN, ORPHENADRINE HYDROCHLORIDE, PROCAINE HYDROCHLORIDE, PROPAFENONE HYDROCHLORIDE, ROPIVACAINE HYDROCHLORIDE, ZONISAMIDE, PHENACEMIDE, RILUZOLE, ERLOSAMIDE, ARTICAINE, OXCARBAZEPINE, QUINIDINE, MEPIVACAINE, MEXILETINE, BENOXINATE, COCAINE HYDROCHLORIDE, PROCAINE, NERISPIRDINE, PROCAINAMIDE, TETRACAINE, LAMOTRIGINE, DISOPYRAMIDE, ORPHENADRINE, TOCAINIDE, EVENAMIDE, DISOPYRAMIDE PHOSPHATE, MEXILETINE HYDROCHLORIDE, PHENAZOPYRIDINE, ESLICARBAZEPINE ACETATE, CENOBAMATE, LIDOCAINE HYDROCHLORIDE, DRONEDARONE HYDROCHLORIDE, RUFINAMIDE, ETHOTOIN, LIDOCAINE, QUINIDINE GLUCONATE, QUINIDINE SULFATE, PRIMIDONE, RALFINAMIDE, PRILOCAINE, ORPHENADRINE CITRATE, TOPIRAMATE, PHENAZOPYRIDINE HYDROCHLORIDE, DRONEDARONE, FOSPHENYTOIN, CARBAMAZEPINE, COCAINE, AZD9056, PROPAFENONE, PROPARACAINE, JNJ-54175446, CHLOROPROCAINE |
| CMF-42211 | FBN2 | down-regulates | hsa-mir-219 | represses | R-2104 | 41 | 22 | Drugs (7) |
| CMF-42212 | FBN2 | down-regulates | hsa-mir-219 | represses | R-61 | 41 | 22 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)PROBUCOL |
| CMF-42213 | FBN2 | down-regulates | hsa-mir-219 | represses | R-2431 | 41 | 22 | Drugs (2) |
| CMF-42214 | FBN2 | down-regulates | hsa-mir-219 | represses | R-2451 | 41 | 22 | Drugs (14) Regulator Drugs (0)Regulon Drugs (14)TAS0612, DASATINIB, LANATOSIDE C, VANDETANIB, TESEVATINIB, DIGOXIN, JI-101, ACETYLDIGITOXIN, TG100-801, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, REGORAFENIB, ISTAROXIME |
| CMF-42215 | FBN2 | down-regulates | hsa-mir-219 | represses | R-576 | 41 | 22 | Drugs (8) |
| CMF-42216 | FBN2 | down-regulates | hsa-mir-219 | represses | R-651 | 41 | 22 | Drugs (2) |
| CMF-42217 | FBN2 | down-regulates | hsa-mir-219 | represses | R-679 | 41 | 22 | Drugs (8) |
| CMF-42218 | FBN2 | down-regulates | hsa-mir-219 | represses | R-2798 | 41 | 22 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-42219 | FBN2 | down-regulates | hsa-mir-219 | represses | R-2830 | 41 | 22 | Drugs (2) |
| CMF-42220 | FBN2 | down-regulates | hsa-mir-219 | represses | R-2864 | 41 | 22 | Drugs (2) |
| CMF-42221 | FBN2 | down-regulates | hsa-mir-219 | represses | R-2883 | 41 | 22 | Drugs (8) |
| CMF-42222 | FBN2 | down-regulates | hsa-mir-219 | represses | R-2940 | 41 | 22 | Drugs (2) |
| CMF-42223 | FBN2 | down-regulates | hsa-mir-219 | represses | R-970 | 41 | 22 | Drugs (8) |
| CMF-42224 | FBN2 | down-regulates | hsa-mir-219 | represses | R-3031 | 41 | 22 | Drugs (2) |
| CMF-42225 | FBN2 | down-regulates | hsa-mir-219 | represses | R-3033 | 41 | 22 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-42226 | FBN2 | down-regulates | hsa-mir-219 | represses | R-3072 | 41 | 22 | Drugs (2) |
| CMF-42227 | FBN2 | down-regulates | hsa-mir-219 | represses | R-3180 | 41 | 22 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)ANG1005 |
| CMF-42228 | FBN2 | down-regulates | hsa-mir-219 | represses | R-3481 | 41 | 22 | Drugs (4) |
| CMF-42229 | FBN2 | down-regulates | hsa-mir-219 | represses | R-3604 | 41 | 22 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)PROBUCOL |
| CMF-42230 | FBN2 | down-regulates | hsa-mir-219 | represses | R-1853 | 41 | 22 | Drugs (8) |
| CMF-42231 | FBN2 | down-regulates | hsa-mir-219 | represses | R-718 | 41 | 22 | Drugs (71) Regulator Drugs (0)Regulon Drugs (71)ESTROGENS, ESTERIFIED, SAVOLITINIB, TELISOTUZUMAB VEDOTIN, ATN-161, RALOXIFENE, PRINABEREL, LASOFOXIFENE, AMUVATINIB, BAZEDOXIFENE ACETATE, CHLOROTRIANISENE, ESTRIOL, BIRINAPANT, ACOLBIFENE, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, SYNTHETIC CONJUGATED ESTROGENS, B, OSPEMIFENE, TEPOTINIB HYDROCHLORIDE, TOREMIFENE CITRATE, FORETINIB, RALOXIFENE HYDROCHLORIDE, ONARTUZUMAB, SAR-125844, ERTEBEREL, AMG-208, FULVESTRANT, CILENGITIDE, TIROFIBAN HYDROCHLORIDE, ESTROGENS, CONJUGATED SYNTHETIC A, ESTROGENS, CONJUGATED, MK-8033, FISPEMIFENE, AMG-337, ABCIXIMAB, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, AFIMOXIFENE, MK-2461, MERESTINIB, DIETHYLSTILBESTROL DIPHOSPHATE, BMS-777607, BAZEDOXIFENE, CAPMATINIB, ETARACIZUMAB, JNJ-38877605, GLESATINIB, INTETUMUMAB, BMS-817378, CABOZANTINIB S-MALATE, MF101, AUS-131, CRIZOTINIB, TOREMIFENE, EMD-1204831, TIVANTINIB, ESTRAMUSTINE PHOSPHATE, NEDOSIRAN SODIUM, TELISOTUZUMAB, ESTETROL, TEPOTINIB, EMIBETUZUMAB, BPI-9016, ESTRAMUSTINE PHOSPHATE SODIUM, PF-04217903, ARZOXIFENE, EPTIFIBATIDE, ABITUZUMAB, GOLVATINIB, TIROFIBAN |
| CMF-42232 | FBN2 | down-regulates | hsa-mir-219 | represses | R-3012 | 41 | 22 | Drugs (70) Regulator Drugs (0)Regulon Drugs (70)ESTROGENS, ESTERIFIED, SAVOLITINIB, TELISOTUZUMAB VEDOTIN, ATN-161, RALOXIFENE, PRINABEREL, LASOFOXIFENE, AMUVATINIB, BAZEDOXIFENE ACETATE, CHLOROTRIANISENE, ESTRIOL, BIRINAPANT, ACOLBIFENE, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, SYNTHETIC CONJUGATED ESTROGENS, B, OSPEMIFENE, TEPOTINIB HYDROCHLORIDE, TOREMIFENE CITRATE, FORETINIB, RALOXIFENE HYDROCHLORIDE, ONARTUZUMAB, SAR-125844, ERTEBEREL, AMG-208, FULVESTRANT, CILENGITIDE, TIROFIBAN HYDROCHLORIDE, ESTROGENS, CONJUGATED SYNTHETIC A, ESTROGENS, CONJUGATED, MK-8033, FISPEMIFENE, AMG-337, ABCIXIMAB, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, AFIMOXIFENE, MK-2461, MERESTINIB, DIETHYLSTILBESTROL DIPHOSPHATE, BMS-777607, BAZEDOXIFENE, CAPMATINIB, ETARACIZUMAB, JNJ-38877605, GLESATINIB, INTETUMUMAB, BMS-817378, CABOZANTINIB S-MALATE, MF101, AUS-131, CRIZOTINIB, TOREMIFENE, EMD-1204831, TIVANTINIB, ESTRAMUSTINE PHOSPHATE, TELISOTUZUMAB, ESTETROL, TEPOTINIB, EMIBETUZUMAB, BPI-9016, ESTRAMUSTINE PHOSPHATE SODIUM, PF-04217903, ARZOXIFENE, EPTIFIBATIDE, ABITUZUMAB, GOLVATINIB, TIROFIBAN |