| CMF-03642 | DSP | down-regulates | NKX2-8 | represses | R-666 | 12 | 8 | Drugs (11) Regulator Drugs (0)Regulon Drugs (11)PRAMLINTIDE, EPELSIBAN, OXYTOCIN, PRAMLINTIDE ACETATE, CARBETOCIN, NOLASIBAN, ATOSIBAN, FE 202767, BARUSIBAN, RETOSIBAN, DAVALINTIDE |
| CMF-03662 | DSP | up-regulates | MTF1 | activates | R-983 | 23 | 11 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |
| CMF-03668 | DSP | up-regulates | STAT3 | activates | R-1535 | 25 | 7 | Drugs (12) Regulator Drugs (0)Regulon Drugs (12)INTERFERON BETA-1B, ANIFROLUMAB, INTERFERON ALFA-2A, INTERFERON ALFA-2B, PEGINTERFERON ALFA-2B, INTERFERON ALFA-N3, ALBINTERFERON ALFA-2B, INTERFERON ALFACON-1, ROPEGINTERFERON ALFA-2B, PEGINTERFERON ALFA-2A, PEGINTERFERON BETA-1A, INTERFERON BETA-1A |
| CMF-03672 | DSP | up-regulates | STAT3 | activates | R-1539 | 25 | 7 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-03675 | DSP | up-regulates | NR2E1 | activates | R-2391 | 9 | 6 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)ASK-8007 |
| CMF-03680 | DSP | up-regulates | LHX2 | activates | R-3707 | 7 | 2 | Drugs (5) |
| CMF-03683 | DSP | up-regulates | ARID5B | activates | R-3006 | 4 | 2 | Drugs (33) Regulator Drugs (0)Regulon Drugs (33)SAVOLITINIB, TELISOTUZUMAB VEDOTIN, AMUVATINIB, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, MK-8033, AMG-337, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, JNJ-38877605, GLESATINIB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, GOLVATINIB |
| CMF-03684 | DSP | up-regulates | NFKB1 | activates | R-297 | 25 | 13 | Drugs (6) |
| CMF-03687 | DSP | up-regulates | NFKB1 | activates | R-302 | 25 | 13 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-03692 | DSP | up-regulates | NFKB1 | activates | R-292 | 25 | 13 | Drugs (20) Regulator Drugs (0)Regulon Drugs (20)GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN |
| CMF-03693 | DSP | up-regulates | NFKB1 | activates | R-290 | 25 | 13 | Drugs (110) Regulator Drugs (0)Regulon Drugs (110)PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR |
| CMF-03695 | DSP | up-regulates | NFKB1 | activates | R-299 | 25 | 13 | Drugs (6) |
| CMF-03702 | DSP | down-regulates | LHX1 | represses | R-2972 | 17 | 8 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-03708 | DSP | down-regulates | FOXD3 | represses | R-576 | 25 | 15 | Drugs (8) |
| CMF-03711 | DSP | down-regulates | FOXD3 | represses | R-577 | 25 | 15 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-03731 | DSP | down-regulates | FOXL1 | represses | R-1848 | 25 | 17 | Drugs (110) Regulator Drugs (0)Regulon Drugs (110)CISATRACURIUM, PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, GSK-1995057, RUPATADINE, DOXYLAMINE SUCCINATE, CISATRACURIUM BESYLATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, SUXAMETHONIUM, PRAMLINTIDE, CYPROHEPTADINE HYDROCHLORIDE, BRINZOLAMIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, MIVACURIUM, EBASTINE, SULTHIAME, CINNARIZINE, HYDROXYZINE, LORATADINE, DORZOLAMIDE, LY2624803, ROCURONIUM BROMIDE, PHENIRAMINE MALEATE, ACETAZOLAMIDE, TRIPROLIDINE HYDROCHLORIDE, METHAZOLAMIDE, MIVACURIUM CHLORIDE, PRAMLINTIDE ACETATE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, TISOTUMAB VEDOTIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, TOPIRAMATE, VANTICTUMAB, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, ACETAZOLAMIDE SODIUM, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, POLMACOXIB, ROCURONIUM, CETIRIZINE, METHDILAZINE, DAVALINTIDE |
| CMF-03732 | DSP | down-regulates | FOXL1 | represses | R-1853 | 25 | 17 | Drugs (8) |
| CMF-03749 | DSP | up-regulates | ZNF263 | activates | R-557 | 20 | 10 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-03752 | DSP | up-regulates | SREBF1 | activates | R-2503 | 12 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-03753 | DSP | up-regulates | SREBF1 | activates | R-2504 | 12 | 3 | Drugs (6) |
| CMF-03755 | DSP | up-regulates | MAF | activates | R-185 | 19 | 8 | Drugs (1) |
| CMF-03757 | DSP | up-regulates | MAF | activates | R-173 | 19 | 8 | Drugs (89) Regulator Drugs (0)Regulon Drugs (89)PF-04691502, FOSTAMATINIB DISODIUM, INFLIXIMAB, UMBRALISIB, FIBOFLAPON SODIUM, BGT-226, SONOLISIB, PARSACLISIB, INTERFERON GAMMA-1B, ONERCEPT, R-343, VOXTALISIB, CINTREDEKIN BESUDOTOX, NEMIRALISIB, RP-6530, APITOLISIB, AME-133V, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, R-348, PEGSUNERCEPT, GOLIMUMAB, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, CERDULATINIB, DUVELISIB, L19TNFA, EFALIZUMAB, DACTOLISIB, ZANDELISIB, HMPL-523, ETANERCEPT, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, OZORALIZUMAB, PILARALISIB, DAPANSUTRILE, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, GEDATOLISIB, OMIPALISIB, UMBRALISIB TOSYLATE, NEIHULIZUMAB, IDELALISIB, AZD4818, FIMEPINOSTAT, ENTOSPLETINIB, R-333, GUSACITINIB, REMTOLUMAB, ERITORAN TETRASODIUM, TOMIVOSERTIB, LIFITEGRAST, ACALISIB, MIVAVOTINIB CITRATE, VELIFLAPON, BMS-817399, OCRIPLASMIN, CAL-263, ERITORAN, ADALIMUMAB, MILATUZUMAB, FOSTAMATINIB, LENIOLISIB, PA-799, PLACULUMAB, GSK-1059615, LANRAPLENIB, MIVAVOTINIB, BUPARLISIB, VESENCUMAB, SF-1126, FIBOFLAPON, PANULISIB |
| CMF-03759 | DSP | up-regulates | MAF | activates | R-176 | 19 | 8 | Drugs (1) |
| CMF-03765 | DSP | up-regulates | NR3C1 | activates | R-2031 | 21 | 8 | Drugs (102) Regulator Drugs (0)Regulon Drugs (102)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, GSK-1995057, RUPATADINE, DOXYLAMINE SUCCINATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, DICHLORPHENAMIDE, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, EBASTINE, SULTHIAME, CINNARIZINE, HYDROXYZINE, LORATADINE, EPELSIBAN, LY2624803, PHENIRAMINE MALEATE, ACETAZOLAMIDE, TRIPROLIDINE HYDROCHLORIDE, OXYTOCIN, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, CARBETOCIN, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, TISOTUMAB VEDOTIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, NOLASIBAN, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, VANTICTUMAB, BROMODIPHENHYDRAMINE, ATOSIBAN, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, FE 202767, MIZOLASTINE, HYDROXYZINE PAMOATE, BARUSIBAN, ALCAFTADINE, ACETAZOLAMIDE SODIUM, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, CETIRIZINE, RETOSIBAN, METHDILAZINE |
| CMF-03771 | DSP | up-regulates | NR3C1 | activates | R-2043 | 21 | 8 | Drugs (8) |
| CMF-03778 | DSP | down-regulates | POU2F3 | represses | R-1706 | 16 | 12 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)2X-121 |
| CMF-03785 | DSP | down-regulates | LMX1B | represses | R-2931 | 11 | 6 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-03796 | DSP | down-regulates | HOXA3 | represses | R-1460 | 22 | 9 | Drugs (44) Regulator Drugs (0)Regulon Drugs (44)SAVOLITINIB, TELISOTUZUMAB VEDOTIN, ATN-161, AMUVATINIB, BIRINAPANT, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, CILENGITIDE, TIROFIBAN HYDROCHLORIDE, MK-8033, AMG-337, ABCIXIMAB, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, ETARACIZUMAB, JNJ-38877605, GLESATINIB, INTETUMUMAB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, NEDOSIRAN SODIUM, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, EPTIFIBATIDE, ABITUZUMAB, GOLVATINIB, TIROFIBAN |
| CMF-03798 | DSP | down-regulates | HOXA3 | represses | R-1476 | 22 | 9 | Drugs (1) |
| CMF-03803 | DSP | down-regulates | FEV | represses | R-3030 | 5 | 1 | Drugs (71) Regulator Drugs (0)Regulon Drugs (71)ESTROGENS, ESTERIFIED, SAVOLITINIB, TELISOTUZUMAB VEDOTIN, ATN-161, RALOXIFENE, PRINABEREL, LASOFOXIFENE, AMUVATINIB, BAZEDOXIFENE ACETATE, CHLOROTRIANISENE, ESTRIOL, BIRINAPANT, ACOLBIFENE, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, SYNTHETIC CONJUGATED ESTROGENS, B, OSPEMIFENE, TEPOTINIB HYDROCHLORIDE, TOREMIFENE CITRATE, FORETINIB, RALOXIFENE HYDROCHLORIDE, ONARTUZUMAB, SAR-125844, ERTEBEREL, AMG-208, FULVESTRANT, CILENGITIDE, TIROFIBAN HYDROCHLORIDE, ESTROGENS, CONJUGATED SYNTHETIC A, ESTROGENS, CONJUGATED, MK-8033, FISPEMIFENE, AMG-337, ABCIXIMAB, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, AFIMOXIFENE, MK-2461, MERESTINIB, DIETHYLSTILBESTROL DIPHOSPHATE, BMS-777607, BAZEDOXIFENE, CAPMATINIB, ETARACIZUMAB, JNJ-38877605, GLESATINIB, INTETUMUMAB, BMS-817378, CABOZANTINIB S-MALATE, MF101, AUS-131, CRIZOTINIB, TOREMIFENE, EMD-1204831, TIVANTINIB, ESTRAMUSTINE PHOSPHATE, NEDOSIRAN SODIUM, TELISOTUZUMAB, ESTETROL, TEPOTINIB, EMIBETUZUMAB, BPI-9016, ESTRAMUSTINE PHOSPHATE SODIUM, PF-04217903, ARZOXIFENE, EPTIFIBATIDE, ABITUZUMAB, GOLVATINIB, TIROFIBAN |
| CMF-03804 | DSP | up-regulates | MEF2A | activates | R-2887 | 25 | 14 | Drugs (7) |
| CMF-03812 | DSP | up-regulates | MEF2A | activates | R-2883 | 25 | 14 | Drugs (8) |
| CMF-03833 | DSP | up-regulates | MEOX2 | activates | R-2199 | 14 | 8 | Drugs (59) Regulator Drugs (0)Regulon Drugs (59)IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN |
| CMF-03835 | DSP | up-regulates | MEOX2 | activates | R-2202 | 14 | 8 | Drugs (5) |
| CMF-03838 | DSP | down-regulates | TFAP2C | represses | R-1340 | 15 | 6 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-03843 | DSP | down-regulates | ESR1 | represses | R-1188 | 7 | 2 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-03845 | DSP | up-regulates | NR3C2 | activates | R-2018 | 2 | 1 | Drugs (3) |
| CMF-03848 | DSP | down-regulates | PAX7 | represses | R-3698 | 3 | 2 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-03852 | DSP | up-regulates | SMAD3 | activates | R-2550 | 15 | 4 | Drugs (1) |
| CMF-03854 | DSP | down-regulates | EMX1 | represses | R-3049 | 14 | 8 | Drugs (59) Regulator Drugs (0)Regulon Drugs (59)IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN |
| CMF-03860 | DSP | down-regulates | EMX1 | represses | R-3048 | 14 | 8 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-03877 | DSP | down-regulates | GATA6 | represses | R-1253 | 18 | 10 | Drugs (9) |
| CMF-03880 | DSP | down-regulates | GATA6 | represses | R-1248 | 18 | 10 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)GSK-1995057, PRAMLINTIDE, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, VARESPLADIB METHYL, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, PRAMLINTIDE ACETATE, TOPIRAMATE, VANTICTUMAB, ACETAZOLAMIDE SODIUM, POLMACOXIB, DAVALINTIDE |
| CMF-03887 | DSP | down-regulates | HOXB13 | represses | R-3240 | 15 | 10 | Drugs (2) |
| CMF-03892 | DSP | down-regulates | HOXB8 | represses | R-1699 | 7 | 4 | Drugs (28) Regulator Drugs (0)Regulon Drugs (28)RUXOLITINIB, PACRITINIB, LONAFARNIB, IZENCITINIB, TOFACITINIB, GANDOTINIB, RUXOLITINIB PHOSPHATE, PEFICITINIB, FORIGERIMOD, TIPIFARNIB, LESTAURTINIB, AC-430, MOMELOTINIB, NS-018, BARICITINIB, BMS-911543, UPADACITINIB, FEDRATINIB HYDROCHLORIDE, ZOTIRACICLIB, TOFACITINIB CITRATE, FORIGERIMOD ACETATE, GUSACITINIB, XL-019, AZD-1480, DELGOCITINIB, OCRIPLASMIN, AT-9283, FEDRATINIB |
| CMF-03897 | DSP | up-regulates | PARP1 | activates | R-2372 | 11 | 6 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-03900 | DSP | up-regulates | PARP1 | activates | R-2374 | 11 | 6 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-03901 | DSP | down-regulates | BARX2 | represses | R-1755 | 7 | 3 | Drugs (6) |
| CMF-03906 | DSP | down-regulates | FOXD2 | represses | R-2583 | 6 | 6 | Drugs (1) |
| CMF-03915 | DSP | up-regulates | YY1 | activates | R-62 | 25 | 8 | Drugs (3) |
| CMF-03920 | DSP | up-regulates | CEBPA | activates | R-2603 | 21 | 13 | Drugs (4) |
| CMF-03925 | DSP | up-regulates | CEBPA | activates | R-2596 | 21 | 13 | Drugs (6) |
| CMF-03926 | DSP | up-regulates | CEBPA | activates | R-2587 | 21 | 13 | Drugs (7) |
| CMF-03932 | DSP | up-regulates | NFE2L2 | activates | R-1379 | 10 | 6 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-03941 | DSP | down-regulates | GATA2 | represses | R-1802 | 4 | 2 | Drugs (14) Regulator Drugs (0)Regulon Drugs (14)GSK-1995057, PRAMLINTIDE, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, PRAMLINTIDE ACETATE, TOPIRAMATE, ACETAZOLAMIDE SODIUM, POLMACOXIB, DAVALINTIDE |
| CMF-03947 | DSP | up-regulates | ELF4 | activates | R-3024 | 20 | 8 | Drugs (12) Regulator Drugs (0)Regulon Drugs (12)INTERFERON BETA-1B, ANIFROLUMAB, INTERFERON ALFA-2A, INTERFERON ALFA-2B, PEGINTERFERON ALFA-2B, INTERFERON ALFA-N3, ALBINTERFERON ALFA-2B, INTERFERON ALFACON-1, ROPEGINTERFERON ALFA-2B, PEGINTERFERON ALFA-2A, PEGINTERFERON BETA-1A, INTERFERON BETA-1A |
| CMF-03949 | DSP | up-regulates | ELF4 | activates | R-3012 | 20 | 8 | Drugs (70) Regulator Drugs (0)Regulon Drugs (70)ESTROGENS, ESTERIFIED, SAVOLITINIB, TELISOTUZUMAB VEDOTIN, ATN-161, RALOXIFENE, PRINABEREL, LASOFOXIFENE, AMUVATINIB, BAZEDOXIFENE ACETATE, CHLOROTRIANISENE, ESTRIOL, BIRINAPANT, ACOLBIFENE, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, SYNTHETIC CONJUGATED ESTROGENS, B, OSPEMIFENE, TEPOTINIB HYDROCHLORIDE, TOREMIFENE CITRATE, FORETINIB, RALOXIFENE HYDROCHLORIDE, ONARTUZUMAB, SAR-125844, ERTEBEREL, AMG-208, FULVESTRANT, CILENGITIDE, TIROFIBAN HYDROCHLORIDE, ESTROGENS, CONJUGATED SYNTHETIC A, ESTROGENS, CONJUGATED, MK-8033, FISPEMIFENE, AMG-337, ABCIXIMAB, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, AFIMOXIFENE, MK-2461, MERESTINIB, DIETHYLSTILBESTROL DIPHOSPHATE, BMS-777607, BAZEDOXIFENE, CAPMATINIB, ETARACIZUMAB, JNJ-38877605, GLESATINIB, INTETUMUMAB, BMS-817378, CABOZANTINIB S-MALATE, MF101, AUS-131, CRIZOTINIB, TOREMIFENE, EMD-1204831, TIVANTINIB, ESTRAMUSTINE PHOSPHATE, TELISOTUZUMAB, ESTETROL, TEPOTINIB, EMIBETUZUMAB, BPI-9016, ESTRAMUSTINE PHOSPHATE SODIUM, PF-04217903, ARZOXIFENE, EPTIFIBATIDE, ABITUZUMAB, GOLVATINIB, TIROFIBAN |
| CMF-03951 | DSP | down-regulates | NKX6-1 | represses | R-2844 | 20 | 15 | Drugs (11) Regulator Drugs (0)Regulon Drugs (11)RIMEGEPANT SULFATE, TELCAGEPANT, ATOGEPANT, UBROGEPANT, ERENUMAB, 2X-121, RIMEGEPANT, BI-44370, MK3207, DAVALINTIDE, OLCEGEPANT |
| CMF-03957 | DSP | down-regulates | NKX6-1 | represses | R-2852 | 20 | 15 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-03961 | DSP | down-regulates | NKX6-1 | represses | R-2849 | 20 | 15 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |
| CMF-03962 | DSP | down-regulates | NKX6-1 | represses | R-2841 | 20 | 15 | Drugs (2) |
| CMF-03966 | DSP | up-regulates | HLTF | activates | R-3419 | 4 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-03972 | DSP | up-regulates | FOXJ2 | activates | R-718 | 17 | 13 | Drugs (71) Regulator Drugs (0)Regulon Drugs (71)ESTROGENS, ESTERIFIED, SAVOLITINIB, TELISOTUZUMAB VEDOTIN, ATN-161, RALOXIFENE, PRINABEREL, LASOFOXIFENE, AMUVATINIB, BAZEDOXIFENE ACETATE, CHLOROTRIANISENE, ESTRIOL, BIRINAPANT, ACOLBIFENE, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, SYNTHETIC CONJUGATED ESTROGENS, B, OSPEMIFENE, TEPOTINIB HYDROCHLORIDE, TOREMIFENE CITRATE, FORETINIB, RALOXIFENE HYDROCHLORIDE, ONARTUZUMAB, SAR-125844, ERTEBEREL, AMG-208, FULVESTRANT, CILENGITIDE, TIROFIBAN HYDROCHLORIDE, ESTROGENS, CONJUGATED SYNTHETIC A, ESTROGENS, CONJUGATED, MK-8033, FISPEMIFENE, AMG-337, ABCIXIMAB, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, AFIMOXIFENE, MK-2461, MERESTINIB, DIETHYLSTILBESTROL DIPHOSPHATE, BMS-777607, BAZEDOXIFENE, CAPMATINIB, ETARACIZUMAB, JNJ-38877605, GLESATINIB, INTETUMUMAB, BMS-817378, CABOZANTINIB S-MALATE, MF101, AUS-131, CRIZOTINIB, TOREMIFENE, EMD-1204831, TIVANTINIB, ESTRAMUSTINE PHOSPHATE, NEDOSIRAN SODIUM, TELISOTUZUMAB, ESTETROL, TEPOTINIB, EMIBETUZUMAB, BPI-9016, ESTRAMUSTINE PHOSPHATE SODIUM, PF-04217903, ARZOXIFENE, EPTIFIBATIDE, ABITUZUMAB, GOLVATINIB, TIROFIBAN |
| CMF-03989 | DSP | down-regulates | FOXC2 | represses | R-2644 | 11 | 8 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-03994 | DSP | down-regulates | PAX2 | represses | R-1183 | 4 | 3 | Drugs (97) Regulator Drugs (0)Regulon Drugs (97)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, RUPATADINE, DOXYLAMINE SUCCINATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, EBASTINE, CINNARIZINE, HYDROXYZINE, LORATADINE, EPELSIBAN, LY2624803, PHENIRAMINE MALEATE, TRIPROLIDINE HYDROCHLORIDE, OXYTOCIN, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, CARBETOCIN, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, TISOTUMAB VEDOTIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, NOLASIBAN, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, VANTICTUMAB, BROMODIPHENHYDRAMINE, ATOSIBAN, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, FE 202767, MIZOLASTINE, HYDROXYZINE PAMOATE, BARUSIBAN, ALCAFTADINE, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, CETIRIZINE, RETOSIBAN, METHDILAZINE |
| CMF-03997 | DSP | down-regulates | IRF4 | represses | R-3772 | 5 | 2 | Drugs (1) |
| CMF-04003 | DSP | up-regulates | REL | activates | R-246 | 8 | 2 | Drugs (63) Regulator Drugs (0)Regulon Drugs (63)PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, ATN-161, BGT-226, SONOLISIB, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, NEMIRALISIB, RP-6530, APITOLISIB, DS-7423, GSK-2269557, INCB-40093, PAXALISIB, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, DUVELISIB, DACTOLISIB, ZANDELISIB, ETANERCEPT, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, OZORALIZUMAB, PILARALISIB, CERTOLIZUMAB PEGOL, TASELISIB, AMG-319, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, FIMEPINOSTAT, REMTOLUMAB, DUPILUMAB, ACALISIB, CAL-263, ADALIMUMAB, VOLOCIXIMAB, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, GSK-1059615, BUPARLISIB, SF-1126, PANULISIB |
| CMF-04007 | DSP | up-regulates | ATF1 | activates | R-457 | 7 | 4 | Drugs (1) |
| CMF-04010 | DSP | up-regulates | BACH1 | activates | R-2748 | 11 | 3 | Drugs (2) |
| CMF-04011 | DSP | up-regulates | BACH1 | activates | R-2747 | 11 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-04012 | DSP | up-regulates | BACH1 | activates | R-2749 | 11 | 3 | Drugs (5) |
| CMF-04014 | DSP | up-regulates | STAT6 | activates | R-2285 | 11 | 4 | Drugs (59) Regulator Drugs (0)Regulon Drugs (59)IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN |
| CMF-04015 | DSP | up-regulates | STAT6 | activates | R-2287 | 11 | 4 | Drugs (6) |
| CMF-04016 | DSP | up-regulates | FOXG1 | represses | R-2836 | 13 | 6 | Drugs (4) |
| CMF-04032 | DSP | down-regulates | HNF1A | represses | R-1784 | 18 | 13 | Drugs (109) Regulator Drugs (0)Regulon Drugs (109)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, GSK-1995057, RUPATADINE, DOXYLAMINE SUCCINATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, BRINZOLAMIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, EBASTINE, SULTHIAME, CINNARIZINE, VARESPLADIB METHYL, HYDROXYZINE, LORATADINE, EPELSIBAN, DORZOLAMIDE, LY2624803, PHENIRAMINE MALEATE, ACETAZOLAMIDE, TRIPROLIDINE HYDROCHLORIDE, METHAZOLAMIDE, OXYTOCIN, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, CARBETOCIN, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, TISOTUMAB VEDOTIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, NOLASIBAN, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, TOPIRAMATE, VANTICTUMAB, BROMODIPHENHYDRAMINE, ATOSIBAN, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, FE 202767, MIZOLASTINE, HYDROXYZINE PAMOATE, BARUSIBAN, ALCAFTADINE, ACETAZOLAMIDE SODIUM, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, POLMACOXIB, CETIRIZINE, RETOSIBAN, METHDILAZINE |
| CMF-04034 | DSP | down-regulates | HNF1A | represses | R-1788 | 18 | 13 | Drugs (10) |
| CMF-04038 | DSP | down-regulates | HNF1A | represses | R-1790 | 18 | 13 | Drugs (18) Regulator Drugs (0)Regulon Drugs (18)BEVACIZUMAB, CONBERCEPT, AMG-780, MEDI-3617, PEGAPTANIB SODIUM, ENIBARCIMAB, TREBANANIB, PEGAPTANIB OCTASODIUM, MUPARFOSTAT, VANUCIZUMAB, PROBUCOL, RANIBIZUMAB, FARICIMAB, CVX-060, ABICIPAR PEGOL, NESVACUMAB, AFLIBERCEPT, BROLUCIZUMAB |
| CMF-04051 | DSP | down-regulates | DLX2 | represses | R-3577 | 4 | 1 | Drugs (7) |