Program – gbmMINER Portal

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Program – gbmMINER Portal

Program

Program Pr-78

Genes (44)

GCLC, CD38, CRYAB, MXI1, OSBPL11, NTRK2, ADD3, ZHX2, STON1, UST, ANKRD6, ISOC1, WNT5A, RALGPS2, RIN2, FRZB, PTPN13, MARCKS, DDX52, USH1C, SNX15, CASP9, MSTN, HNMT, PDZRN4, PRKX, ARHGEF10L, SGK2, GORASP1, THRA, SLC14A1, PDCD4, PBXIP1, PLXNB1, CSDC2, COX15, ROGDI, RGS9, TFEB, FAM63A, PC, TOB2, PLXNB3, CORO7

Regulons (8)

R-558, R-1213, R-1243, R-1442, R-1957, R-2410, R-2719, R-3334

Regulons in program Pr-78

Regulon	Cox Hazard Ratio	# genes	# causal flows
R-558	-1.57657	9	9
R-1213	-2.11638	8	2
R-1243	-0.68984	8	10
R-1442	-2.1557	9	8
R-1957	-1.82308	6	3
R-2410	-0.354025	9	6
R-2719	-1.22132	13	4
R-3334	-2.24264	7	10

Genes in program Pr-78

EnsEMBL Id	Entrez Id	Preferred
ENSG00000001084	2729	GCLC
ENSG00000004468	952	CD38
ENSG00000109846	1410	CRYAB
ENSG00000119950	4601	MXI1
ENSG00000144909	114885	OSBPL11
ENSG00000148053	4915	NTRK2
ENSG00000148700	120	ADD3
ENSG00000178764	22882	ZHX2
ENSG00000243244	11037	STON1
ENSG00000111962	10090	UST
ENSG00000135299	22881	ANKRD6
ENSG00000066583	51015	ISOC1
ENSG00000114251	7474	WNT5A
ENSG00000116191	55103	RALGPS2
ENSG00000132669	54453	RIN2
ENSG00000162998	2487	FRZB
ENSG00000163629	5783	PTPN13
ENSG00000277443	4082	MARCKS
ENSG00000278053	11056	DDX52
ENSG00000006611	10083	USH1C
ENSG00000110025	29907	SNX15
ENSG00000132906	842	CASP9
ENSG00000138379	2660	MSTN
ENSG00000150540	3176	HNMT
ENSG00000165966	29951	PDZRN4
ENSG00000183943	5613	PRKX
ENSG00000074964	55160	ARHGEF10L
ENSG00000101049	10110	SGK2
ENSG00000114745	64689	GORASP1
ENSG00000126351	7067	THRA
ENSG00000141469	6563	SLC14A1
ENSG00000150593	27250	PDCD4
ENSG00000163346	57326	PBXIP1
ENSG00000164050	5364	PLXNB1
ENSG00000172346	27254	CSDC2
ENSG00000014919	1355	COX15
ENSG00000067836	79641	ROGDI
ENSG00000108370	8787	RGS9
ENSG00000112561	7942	TFEB
ENSG00000143409	55793	FAM63A
ENSG00000173599	5091	PC
ENSG00000183864	10766	TOB2
ENSG00000198753	5365	PLXNB3
ENSG00000282725	79585	CORO7

Causal Mechanistic Flows with Program Pr-78

ID	Mutation	Role	Regulator	Role	Regulon	# downstream regulons	# diffexp regulons	Drugs
CMF-08535	MYO3A	down-regulates	GFI1	represses	R-1213	13	3	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-10360	FGG	down-regulates	GFI1	represses	R-1213	13	2	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)

CMFlow summary not available

Enrichment summary not available