Program – gbmMINER Portal

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Program – gbmMINER Portal

Program

Program Pr-51

Genes (51)

QKI, SEMA5A, PLCE1, ZEB1, IPO9, REPIN1, DDR1, SPPL2B, TCF3, CSPG5, PCDH17, CCND2, POMT1, FADS2, C7orf26, NOTCH1, ASTN1, DDAH1, PRR14, DCHS1, NLGN1, CUEDC1, SOX2, ETV1, APC2, BCAN, NOVA1, CDC34, GOLM1, VEZF1, ASCL1, FAM57A, CSPG4, ZNF358, MBD3, ARHGEF10L, TROVE2, TCF12, TCF4, SALL2, PTPRZ1, ARL4A, HEY1, GAP43, LPL, GRIA3, LRP4, ARNT2, ZBTB20, TEAD1, MAGI2

Regulons (17)

R-819, R-872, R-945, R-969, R-1012, R-1393, R-1424, R-1485, R-1677, R-1716, R-2278, R-2319, R-2332, R-2336, R-2340, R-2347, R-2357

Regulons in program Pr-51

Regulon	Cox Hazard Ratio	# genes	# causal flows
R-819	-0.536262	19	11
R-872	-0.726455	15	8
R-945	-0.655053	22	17
R-969	-0.723868	29	7
R-1012	-0.77725	10	10
R-1393	-0.661478	8	4
R-1424	1.15431	5	7
R-1485	-0.756154	21	6
R-1677	-0.647363	16	9
R-1716	0.088278	6	18
R-2278	-0.557204	12	11
R-2319	-0.994181	15	22
R-2332	-1.14926	7	9
R-2336	-0.796913	8	7
R-2340	-0.518474	8	15
R-2347	-0.858916	28	6
R-2357	-0.714705	10	6

Genes in program Pr-51

EnsEMBL Id	Entrez Id	Preferred
ENSG00000112531	9444	QKI
ENSG00000112902	9037	SEMA5A
ENSG00000138193	51196	PLCE1
ENSG00000148516	6935	ZEB1
ENSG00000198700	55705	IPO9
ENSG00000214022	29803	REPIN1
ENSG00000234078	780	DDR1
ENSG00000005206	56928	SPPL2B
ENSG00000071564	6929	TCF3
ENSG00000114646	10675	CSPG5
ENSG00000118946	27253	PCDH17
ENSG00000118971	894	CCND2
ENSG00000130714	10585	POMT1
ENSG00000134824	9415	FADS2
ENSG00000146576	79034	C7orf26
ENSG00000148400	4851	NOTCH1
ENSG00000152092	460	ASTN1
ENSG00000153904	23576	DDAH1
ENSG00000156858	78994	PRR14
ENSG00000166341	8642	DCHS1
ENSG00000169760	22871	NLGN1
ENSG00000180891	404093	CUEDC1
ENSG00000181449	6657	SOX2
ENSG00000006468	2115	ETV1
ENSG00000115266	10297	APC2
ENSG00000132692	63827	BCAN
ENSG00000139910	4857	NOVA1
ENSG00000099804	997	CDC34
ENSG00000135052	51280	GOLM1
ENSG00000136451	7716	VEZF1
ENSG00000139352	429	ASCL1
ENSG00000167695	79850	FAM57A
ENSG00000173546	1464	CSPG4
ENSG00000198816	140467	ZNF358
ENSG00000071655	53615	MBD3
ENSG00000074964	55160	ARHGEF10L
ENSG00000116747	6738	TROVE2
ENSG00000140262	6938	TCF12
ENSG00000196628	6925	TCF4
ENSG00000165821	6297	SALL2
ENSG00000106278	5803	PTPRZ1
ENSG00000122644	10124	ARL4A
ENSG00000164683	23462	HEY1
ENSG00000172020	2596	GAP43
ENSG00000175445	4023	LPL
ENSG00000125675	2892	GRIA3
ENSG00000134569	4038	LRP4
ENSG00000172379	9915	ARNT2
ENSG00000181722	26137	ZBTB20
ENSG00000187079	7003	TEAD1
ENSG00000187391	9863	MAGI2

Causal Mechanistic Flows with Program Pr-51

ID	Mutation	Role	Regulator	Role	Regulon	# downstream regulons	# diffexp regulons	Drugs

CMFlow summary not available

Enrichment summary not available