Program – gbmMINER Portal

Program Pr-14

Genes (62)

CFLAR, PARP4, FKBP15, TMEM2, GNS, BNIP2, ADAM28, SOAT1, DNAJC10, ASAH1, ELF1, FGL2, PNRC1, DIAPH2, BACH1, SEPP1, IBTK, ABCC4, ATP8B4, OSTM1, ME2, PMFBP1, BTG1, CPM, TPM3, HEATR3, IFNAR2, HSD17B11, ISOC1, HPS5, WNT5A, TMED5, RIN2, RBMS2, ZNF331, NUMB, ETS1, ACE, C8orf4, GCA, SNX13, APLP2, JAK2, PFN1, RNF141, HIPK3, SORT1, SCRN3, OSMR, SLC15A2, OLR1, KCNJ10, LYN, FNTB, HSPA8, PTGES3, SLC29A1, LCP1, TLR4, CLIC4, GM2A, PABPC4

Regulons (24)

R-13, R-125, R-199, R-287, R-335, R-368, R-433, R-593, R-662, R-1124, R-1265, R-1310, R-1475, R-1863, R-1915, R-2099, R-2220, R-2447, R-2608, R-2857, R-2968, R-3215, R-3468, R-3699

Regulons in program Pr-14

Regulon	Cox Hazard Ratio	# genes	# causal flows
R-13	2.47912	6	26
R-125	1.13576	12	29
R-199	1.70454	5	8
R-287	0.602443	6	6
R-335	1.40826	9	44
R-368	2.18239	5	8
R-433	1.1238	10	49
R-593	2.06552	9	32
R-662	0.547661	9	5
R-1124	0.0148635	5	16
R-1265	2.46093	5	9
R-1310	1.19679	10	5
R-1475	1.88405	6	5
R-1863	1.05816	14	7
R-1915	1.52491	10	8
R-2099	2.12394	14	10
R-2220	1.26155	8	7
R-2447	1.82764	8	5
R-2608	1.29253	12	10
R-2857	1.03481	6	11
R-2968	1.58162	6	17
R-3215	1.03032	8	3
R-3468	0.434295	10	6
R-3699	1.08444	5	43

Genes in program Pr-14

EnsEMBL Id	Entrez Id	Preferred
ENSG00000003402	8837	CFLAR
ENSG00000102699	143	PARP4
ENSG00000119321	23307	FKBP15
ENSG00000135048	23670	TMEM2
ENSG00000135677	2799	GNS
ENSG00000140299	663	BNIP2
ENSG00000042980	10863	ADAM28
ENSG00000057252	6646	SOAT1
ENSG00000077232	54431	DNAJC10
ENSG00000104763	427	ASAH1
ENSG00000120690	1997	ELF1
ENSG00000127951	10875	FGL2
ENSG00000146278	10957	PNRC1
ENSG00000147202	1730	DIAPH2
ENSG00000156273	571	BACH1
ENSG00000250722	6414	SEPP1
ENSG00000283068	25998	IBTK
ENSG00000125257	10257	ABCC4
ENSG00000104043	79895	ATP8B4
ENSG00000081087	28962	OSTM1
ENSG00000082212	4200	ME2
ENSG00000118557	83449	PMFBP1
ENSG00000133639	694	BTG1
ENSG00000135678	1368	CPM
ENSG00000143549	7170	TPM3
ENSG00000155393	55027	HEATR3
ENSG00000159110	3455	IFNAR2
ENSG00000198189	51170	HSD17B11
ENSG00000066583	51015	ISOC1
ENSG00000110756	11234	HPS5
ENSG00000114251	7474	WNT5A
ENSG00000117500	50999	TMED5
ENSG00000132669	54453	RIN2
ENSG00000076067	5939	RBMS2
ENSG00000130844	55422	ZNF331
ENSG00000133961	8650	NUMB
ENSG00000134954	2113	ETS1
ENSG00000159640	1636	ACE
ENSG00000176907	56892	C8orf4
ENSG00000115271	25801	GCA
ENSG00000071189	23161	SNX13
ENSG00000084234	334	APLP2
ENSG00000096968	3717	JAK2
ENSG00000108518	5216	PFN1
ENSG00000110315	50862	RNF141
ENSG00000110422	10114	HIPK3
ENSG00000134243	6272	SORT1
ENSG00000144306	79634	SCRN3
ENSG00000145623	9180	OSMR
ENSG00000163406	6565	SLC15A2
ENSG00000173391	4973	OLR1
ENSG00000177807	3766	KCNJ10
ENSG00000254087	4067	LYN
ENSG00000257365	2342	FNTB
ENSG00000109971	3312	HSPA8
ENSG00000110958	10728	PTGES3
ENSG00000112759	2030	SLC29A1
ENSG00000136167	3936	LCP1
ENSG00000136869	7099	TLR4
ENSG00000169504	25932	CLIC4
ENSG00000196743	2760	GM2A
ENSG00000090621	8761	PABPC4

Causal Mechanistic Flows with Program Pr-14

ID	Mutation	Role	Regulator	Role	Regulon	# downstream regulons	# diffexp regulons	Drugs

CMFlow summary not available

Enrichment summary not available