Program

Program Pr-132

Genes (216)

CDC27, AQR, DNAJC7, NBR1, SDAD1, MED17, DHX8, DDX18, CNOT6, RAD50, PDS5A, NUP153, HMG20A, CSNK1G3, DDX19A, TRRAP, DDX3X, RBM14, PRKDC, CLINT1, EDEM3, CANX, USP8, ARFIP1, AGPS, THRAP3, GSR, EXOC2, NNT, ARMC8, XPO7, EIF2S3, UBE4B, CAPN7, ROCK2, TMOD3, G3BP2, SS18, EML4, SMARCA5, GNAQ, DEDD, SENP2, API5, TBL1XR1, PAK2, MCCC2, EXOC5, FBXW11, ZNF510, PPP2R5D, CREB1, TBC1D5, DCTN4, SENP7, SCARB2, FER, LIG4, RAB6A, TJP1, PGD, PEX10, DFFA, HSPA4L, DCAKD, LARP7, TOR1AIP1, PKN2, ARHGAP5, CLCC1, DENND4C, ETAA1, DNAJB14, CLPX, ANKFY1, TLK1, LRBA, RNGTT, TUBGCP4, FAM63B, TPP2, USP6NL, GLUD1, TCF7L2, CDYL, NADK, OGDH, RFC1, SRBD1, C5orf22, OSBP, NUP98, CPSF6, PRPF4B, ANKRD17, STX6, KCTD3, SMC2, UBAP2L, G3BP1, TLK2, CKAP5, RBM15B, RPAP3, YTHDC2, SPG11, LARP4, DENND4A, TUBGCP5, MAP3K7, ADAM10, PTPN21, MAPRE1, CCDC47, CLCN3, KCTD20, SCYL2, ZNF225, ZFX, RFX3, POLI, TAF1A, TMF1, ZBTB6, KPNA6, TMEM87A, ZFAND5, RAB35, RAB14, IPO8, RNF121, POGK, DLAT, ZNF148, MRFAP1L1, DIS3, WBP4, ZNF426, IK, CYP51A1, GNAI3, PHKB, NBN, RDX, HS2ST1, USP16, ARFGEF1, AP3B1, KPNA4, CDC14A, IFT74, STAG2, RPGRIP1L, ACADL, RCBTB2, PAFAH1B1, SGPP1, KARS, ZW10, CDC5L, PRMT5, CSTF1, NOL11, PRPF4, ABI2, MFAP1, NUP205, OXSR1, DLG1, PIAS2, RIF1, SEH1L, UFM1, RINT1, C2orf49, IREB2, ANP32E, FBXO38, SMG1, GTF2A1, CUL5, EIF2AK3, VPS13A, RORB, IBTK, GAB1, ELP3, ZNF24, RTF1, SMG7, AATF, FKBP14, MSH3, FBXW2, SLC35E1, GPR107, APPBP2, ELF2, KPNA1, PRKD3, YES1, RBBP4, HIBCH, UBE3C, SRCAP, EYA3, NEDD4, PRRX1, PIK3CA, CHD1L, GALK2, THAP9, CLCN5, ERCC4, ZBTB33, TAF9B

Regulons (71)

R-2, R-15, R-28, R-116, R-262, R-311, R-345, R-427, R-485, R-498, R-535, R-624, R-630, R-681, R-716, R-800, R-816, R-844, R-971, R-975, R-1093, R-1157, R-1165, R-1201, R-1292, R-1415, R-1429, R-1431, R-1440, R-1489, R-1616, R-1626, R-1650, R-1742, R-1764, R-1811, R-1824, R-1832, R-1845, R-1849, R-1851, R-1859, R-1998, R-2154, R-2165, R-2209, R-2215, R-2217, R-2292, R-2373, R-2398, R-2434, R-2514, R-2646, R-2665, R-2791, R-2865, R-2978, R-3026, R-3075, R-3230, R-3234, R-3294, R-3422, R-3434, R-3471, R-3485, R-3506, R-3530, R-3531, R-3638


Regulons in program Pr-132

Regulon Cox Hazard Ratio # genes # causal flows
R-20.40849255
R-15-0.1865611416
R-281.05011510
R-1160.114288261
R-262-0.597966139
R-3110.25060968
R-3450.896326632
R-4270.3535271439
R-485-0.932722710
R-498-2.86625610
R-5350.68480154
R-624-0.118921302
R-6300.301292205
R-681-0.150989168
R-716-1.3364875
R-8000.1475751012
R-8160.553574610
R-8440.24635856
R-9710.0521235279
R-975-0.5159151711
R-1093-0.092757494
R-1157-0.8417159
R-11650.235679197
R-1201-0.992611713
R-1292-0.24581374
R-14150.18551894
R-14290.254549325
R-14310.233656215
R-1440-0.441689115
R-14890.1967551411
R-1616-0.276998811
R-16260.212001283
R-16500.166254154
R-17420.0691339112
R-1764-0.36179652
R-1811-0.708242236
R-18241.00452510
R-1832-0.26265193
R-18450.943974
R-1849-0.121138346
R-1851-0.375145326
R-1859-0.461331184
R-19980.33261166
R-21541.7061752
R-21650.156997166
R-22090.156067158
R-2215-0.1651021010
R-2217-0.02074941016
R-22920.1806484
R-23730.47109910
R-2398-0.08153431012
R-24340.535992156
R-25140.39609595
R-26460.0121632155
R-2665-0.33781520
R-2791-0.529816711
R-28650.257125158
R-2978-0.049627451
R-30261.1470495
R-30750.1447117
R-32300.00071976153
R-32340.3881521113
R-3294-0.23223387
R-34220.11961957
R-34340.857402510
R-3471-0.55902994
R-3485-0.41689879
R-3506-2.3311353
R-35300.061150355
R-3531-1.235457
R-3638-1.6791368

Genes in program Pr-132

EnsEMBL IdEntrez IdPreferred
ENSG00000004897 996CDC27
ENSG00000021776 9716AQR
ENSG00000168259 7266DNAJC7
ENSG00000188554 4077NBR1
ENSG00000198301 55153SDAD1
ENSG00000042429 9440MED17
ENSG00000067596 1659DHX8
ENSG00000088205 8886DDX18
ENSG00000113300 57472CNOT6
ENSG00000113522 10111RAD50
ENSG00000121892 23244PDS5A
ENSG00000124789 9972NUP153
ENSG00000140382 10363HMG20A
ENSG00000151292 1456CSNK1G3
ENSG00000168872 55308DDX19A
ENSG00000196367 8295TRRAP
ENSG00000215301 1654DDX3X
ENSG00000239306 10432RBM14
ENSG00000253729 5591PRKDC
ENSG00000113282 9685CLINT1
ENSG00000116406 80267EDEM3
ENSG00000127022 821CANX
ENSG00000138592 9101USP8
ENSG00000164144 27236ARFIP1
ENSG00000018510 8540AGPS
ENSG00000054118 9967THRAP3
ENSG00000104687 2936GSR
ENSG00000112685 55770EXOC2
ENSG00000112992 23530NNT
ENSG00000114098 25852ARMC8
ENSG00000130227 23039XPO7
ENSG00000130741 1968EIF2S3
ENSG00000130939 10277UBE4B
ENSG00000131375 23473CAPN7
ENSG00000134318 9475ROCK2
ENSG00000138594 29766TMOD3
ENSG00000138757 9908G3BP2
ENSG00000141380 6760SS18
ENSG00000143924 27436EML4
ENSG00000153147 8467SMARCA5
ENSG00000156052 2776GNAQ
ENSG00000158796 9191DEDD
ENSG00000163904 59343SENP2
ENSG00000166181 8539API5
ENSG00000177565 79718TBL1XR1
ENSG00000180370 5062PAK2
ENSG00000281742 64087MCCC2
ENSG00000070367 10640EXOC5
ENSG00000072803 23291FBXW11
ENSG00000081386 22869ZNF510
ENSG00000112640 5528PPP2R5D
ENSG00000118260 1385CREB1
ENSG00000131374 9779TBC1D5
ENSG00000132912 51164DCTN4
ENSG00000138468 57337SENP7
ENSG00000138760 950SCARB2
ENSG00000151422 2241FER
ENSG00000174405 3981LIG4
ENSG00000175582 5870RAB6A
ENSG00000277401 7082TJP1
ENSG00000142657 5226PGD
ENSG00000157911 5192PEX10
ENSG00000160049 1676DFFA
ENSG00000164070 22824HSPA4L
ENSG00000172992 79877DCAKD
ENSG00000174720 51574LARP7
ENSG00000143337 26092TOR1AIP1
ENSG00000065243 5586PKN2
ENSG00000100852 394ARHGAP5
ENSG00000121940 23155CLCC1
ENSG00000137145 55667DENND4C
ENSG00000143971 54465ETAA1
ENSG00000164031 79982DNAJB14
ENSG00000166855 10845CLPX
ENSG00000185722 51479ANKFY1
ENSG00000198586 9874TLK1
ENSG00000198589 987LRBA
ENSG00000111880 8732RNGTT
ENSG00000137822 27229TUBGCP4
ENSG00000128923 54629FAM63B
ENSG00000134900 7174TPP2
ENSG00000148429 9712USP6NL
ENSG00000148672 2746GLUD1
ENSG00000148737 6934TCF7L2
ENSG00000153046 9425CDYL
ENSG00000008130 65220NADK
ENSG00000105953 4967OGDH
ENSG00000035928 5981RFC1
ENSG00000068784 55133SRBD1
ENSG00000082213 55322C5orf22
ENSG00000110048 5007OSBP
ENSG00000110713 4928NUP98
ENSG00000111605 11052CPSF6
ENSG00000112739 8899PRPF4B
ENSG00000132466 26057ANKRD17
ENSG00000135823 10228STX6
ENSG00000136636 51133KCTD3
ENSG00000136824 10592SMC2
ENSG00000143569 9898UBAP2L
ENSG00000145907 10146G3BP1
ENSG00000146872 11011TLK2
ENSG00000175216 9793CKAP5
ENSG00000259956 29890RBM15B
ENSG00000005175 79657RPAP3
ENSG00000047188 64848YTHDC2
ENSG00000104133 80208SPG11
ENSG00000161813 113251LARP4
ENSG00000174485 10260DENND4A
ENSG00000280807 114791TUBGCP5
ENSG00000135341 6885MAP3K7
ENSG00000137845 102ADAM10
ENSG00000070778 11099PTPN21
ENSG00000101367 22919MAPRE1
ENSG00000108588 57003CCDC47
ENSG00000109572 1182CLCN3
ENSG00000112078 222658KCTD20
ENSG00000136021 55681SCYL2
ENSG00000256294 7768ZNF225
ENSG00000005889 7543ZFX
ENSG00000080298 5991RFX3
ENSG00000101751 11201POLI
ENSG00000143498 9015TAF1A
ENSG00000144747 7110TMF1
ENSG00000186130 10773ZBTB6
ENSG00000025800 23633KPNA6
ENSG00000103978 25963TMEM87A
ENSG00000107372 7763ZFAND5
ENSG00000111737 11021RAB35
ENSG00000119396 51552RAB14
ENSG00000133704 10526IPO8
ENSG00000137522 55298RNF121
ENSG00000143157 57645POGK
ENSG00000150768 1737DLAT
ENSG00000163848 7707ZNF148
ENSG00000178988 114932MRFAP1L1
ENSG00000083520 22894DIS3
ENSG00000120688 11193WBP4
ENSG00000130818 79088ZNF426
ENSG00000113141 3550IK
ENSG00000001630 1595CYP51A1
ENSG00000065135 406974GNAI3
ENSG00000102893 5257PHKB
ENSG00000104320 4683NBN
ENSG00000137710 5962RDX
ENSG00000153936 9653HS2ST1
ENSG00000156256 10600USP16
ENSG00000066777 10565ARFGEF1
ENSG00000132842 8546AP3B1
ENSG00000186432 3840KPNA4
ENSG00000079335 8556CDC14A
ENSG00000096872 80173IFT74
ENSG00000101972 10735STAG2
ENSG00000103494 23322RPGRIP1L
ENSG00000115361 33ACADL
ENSG00000136161 1102RCBTB2
ENSG00000007168 5048PAFAH1B1
ENSG00000126821 81537SGPP1
ENSG00000065427 3735KARS
ENSG00000086827 9183ZW10
ENSG00000096401 988CDC5L
ENSG00000100462 10419PRMT5
ENSG00000101138 1477CSTF1
ENSG00000130935 25926NOL11
ENSG00000136875 9128PRPF4
ENSG00000138443 10152ABI2
ENSG00000140259 4236MFAP1
ENSG00000155561 23165NUP205
ENSG00000172939 9943OXSR1
ENSG00000075711 1739DLG1
ENSG00000078043 9063PIAS2
ENSG00000080345 55183RIF1
ENSG00000085415 81929SEH1L
ENSG00000120686 51569UFM1
ENSG00000135249 60561RINT1
ENSG00000135974 79074C2orf49
ENSG00000136381 3658IREB2
ENSG00000143401 81611ANP32E
ENSG00000145868 81545FBXO38
ENSG00000157106 23049SMG1
ENSG00000165417 2957GTF2A1
ENSG00000166266 8065CUL5
ENSG00000172071 9451EIF2AK3
ENSG00000197969 23230VPS13A
ENSG00000198963 6096RORB
ENSG00000283068 25998IBTK
ENSG00000109458 2549GAB1
ENSG00000134014 55140ELP3
ENSG00000172466 7572ZNF24
ENSG00000137815 23168RTF1
ENSG00000116698 9887SMG7
ENSG00000276072 26574AATF
ENSG00000106080 55033FKBP14
ENSG00000113318 4437MSH3
ENSG00000119402 26190FBXW2
ENSG00000127526 79939SLC35E1
ENSG00000148358 57720GPR107
ENSG00000062725 10513APPBP2
ENSG00000109381 1998ELF2
ENSG00000114030 3836KPNA1
ENSG00000115825 23683PRKD3
ENSG00000176105 7525YES1
ENSG00000162521 5928RBBP4
ENSG00000198130 26275HIBCH
ENSG00000009335 9690UBE3C
ENSG00000080603 10847SRCAP
ENSG00000158161 2140EYA3
ENSG00000069869 4734NEDD4
ENSG00000116132 5396PRRX1
ENSG00000121879 5290PIK3CA
ENSG00000131778 9557CHD1L
ENSG00000156958 2585GALK2
ENSG00000168152 79725THAP9
ENSG00000171365 1184CLCN5
ENSG00000175595 2072ERCC4
ENSG00000177485 10009ZBTB33
ENSG00000187325 51616TAF9B

Causal Mechanistic Flows with Program Pr-132

IDMutationRoleRegulatorRoleRegulon# downstream regulons# diffexp regulonsDrugs

CMFlow summary not available


Enrichment summary not available