Pr-122
Genes (99)
TRIM25, KCNK15, OSGIN1, PAPPA, CCIN, KCNK2, TBX5, SH3BP1, LLGL1, CDK4, HAAO, IDH2, CEACAM1, FETUB, CEBPE, MEFV, RHBG, ADAMTS7, IRF4, SEMA7A, GFI1, TBX1, GZMM, CSF3, C11orf21, TGM3, KRT16, SPIB, PRTN3, MXD1, TREML2, CAPN9, CHRND, RORC, PTGIR, CEACAM3, ADRA2B, ITGA2B, CD40LG, FGF5, CD27, FGFR4, PTGER1, SLC25A30, FOXL1, SPN, BDKRB1, HSF2BP, CRYBA4, PTGDR, XDH, DNAH3, CTLA4, PAX9, C8G, IL23A, CAV3, MYOC, TNIP3, DMC1, SLAMF1, EML2, XCL1, PTPRCAP, ATP2A3, ESR1, IL12RB1, LY9, RUNX2, PYHIN1, ICOS, SLC16A5, STARD5, CD28, SH2D1A, CXCR3, ZBP1, CD96, IKZF3, TACSTD2, CCR4, SRD5A2, HAL, GCKR, CLDN1, CYP4F11, PLAG1, MC1R, TNFRSF9, HTR1B, PIK3R5, HUNK, DIO3, MMP11, HES2, IL1RL2, CD160, ADM2, NMUR1Regulons (28)
R-91, R-324, R-439, R-441, R-618, R-842, R-897, R-1122, R-1691, R-1746, R-1804, R-1821, R-2095, R-2238, R-2274, R-2283, R-2414, R-2511, R-2662, R-2695, R-2733, R-2777, R-3005, R-3089, R-3196, R-3515, R-3523, R-3674Regulons in program Pr-122
| Regulon | Cox Hazard Ratio | # genes | # causal flows |
|---|---|---|---|
| R-91 | -0.0191751 | 5 | 6 |
| R-324 | -0.948625 | 7 | 16 |
| R-439 | -0.97202 | 11 | 1 |
| R-441 | -0.0912016 | 6 | 2 |
| R-618 | 0.508117 | 8 | 4 |
| R-842 | -0.646848 | 12 | 14 |
| R-897 | -0.429255 | 8 | 11 |
| R-1122 | -1.60501 | 6 | 15 |
| R-1691 | -0.677506 | 6 | 9 |
| R-1746 | 0.90329 | 7 | 2 |
| R-1804 | 0.559431 | 7 | 18 |
| R-1821 | -1.28633 | 6 | 1 |
| R-2095 | -0.444912 | 5 | 8 |
| R-2238 | 0.111453 | 9 | 15 |
| R-2274 | -0.661537 | 6 | 5 |
| R-2283 | 0.12769 | 7 | 15 |
| R-2414 | 0.0723185 | 5 | 15 |
| R-2511 | -1.00072 | 5 | 9 |
| R-2662 | -2.12634 | 6 | 26 |
| R-2695 | -1.59173 | 10 | 10 |
| R-2733 | -2.36788 | 6 | 10 |
| R-2777 | 1.39433 | 6 | 4 |
| R-3005 | 1.70134 | 5 | 2 |
| R-3089 | 0.416349 | 6 | 6 |
| R-3196 | 0.24387 | 5 | 4 |
| R-3515 | -0.605976 | 14 | 8 |
| R-3523 | -0.259183 | 6 | 4 |
| R-3674 | -2.05093 | 5 | 5 |
Genes in program Pr-122
Causal Mechanistic Flows with Program Pr-122
| ID | Mutation | Role | Regulator | Role | Regulon | # downstream regulons | # diffexp regulons | Drugs |
|---|
CMFlow summary not available
Enrichment summary not available