Program – gbmMINER Portal

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Program – gbmMINER Portal

Program

Program Pr-117

Genes (46)

AVPI1, ANXA3, SLC27A2, SPINT2, CPNE7, SEMA3B, TESK2, RAPGEF3, TSPAN15, RNF125, GJB1, TMEM63A, LRP2, MLPH, HOXD1, FLNB, CDC42EP2, ETS2, LDLRAP1, PRKCD, NINJ2, MYO1D, SLC29A3, GREM1, GLRA2, GABRE, NR4A1, FOSB, KLF4, FRAS1, SNED1, CITED2, SOSTDC1, PRKG1, PLN, SEMA3C, TBC1D2, TSPAN8, PIP4K2A, SEMA4D, SVIL, MAP3K3, ENPP2, LGI2, EGR3, ARFGAP3

Regulons (14)

R-243, R-323, R-951, R-1359, R-2164, R-2264, R-2330, R-2624, R-2831, R-3128, R-3145, R-3312, R-3392, R-3778

Regulons in program Pr-117

Regulon	Cox Hazard Ratio	# genes	# causal flows
R-243	-0.217637	5	12
R-323	-0.0105078	7	13
R-951	0.340924	13	4
R-1359	1.10576	11	13
R-2164	0.0835925	17	11
R-2264	0.16597	11	5
R-2330	-0.195536	5	13
R-2624	0.374623	17	6
R-2831	0.533546	14	16
R-3128	0.03616	15	3
R-3145	-0.262034	5	11
R-3312	1.1473	6	9
R-3392	0.820268	10	43
R-3778	1.60675	8	3

Genes in program Pr-117

EnsEMBL Id	Entrez Id	Preferred
ENSG00000119986	60370	AVPI1
ENSG00000138772	306	ANXA3
ENSG00000140284	11001	SLC27A2
ENSG00000167642	10653	SPINT2
ENSG00000178773	27132	CPNE7
ENSG00000012171	7869	SEMA3B
ENSG00000070759	10420	TESK2
ENSG00000079337	10411	RAPGEF3
ENSG00000099282	23555	TSPAN15
ENSG00000101695	54941	RNF125
ENSG00000169562	2705	GJB1
ENSG00000196187	9725	TMEM63A
ENSG00000081479	4036	LRP2
ENSG00000115648	79083	MLPH
ENSG00000128645	3231	HOXD1
ENSG00000136068	2317	FLNB
ENSG00000149798	10435	CDC42EP2
ENSG00000157557	2114	ETS2
ENSG00000157978	26119	LDLRAP1
ENSG00000163932	5580	PRKCD
ENSG00000171840	4815	NINJ2
ENSG00000176658	4642	MYO1D
ENSG00000198246	55315	SLC29A3
ENSG00000282046	26585	GREM1
ENSG00000101958	2742	GLRA2
ENSG00000102287	574412	GABRE
ENSG00000123358	3164	NR4A1
ENSG00000125740	2354	FOSB
ENSG00000136826	9314	KLF4
ENSG00000138759	80144	FRAS1
ENSG00000162804	25992	SNED1
ENSG00000164442	10370	CITED2
ENSG00000171243	25928	SOSTDC1
ENSG00000185532	5592	PRKG1
ENSG00000198523	5350	PLN
ENSG00000075223	10512	SEMA3C
ENSG00000095383	55357	TBC1D2
ENSG00000127324	7103	TSPAN8
ENSG00000150867	5305	PIP4K2A
ENSG00000187764	10507	SEMA4D
ENSG00000197321	6840	SVIL
ENSG00000198909	4215	MAP3K3
ENSG00000136960	5168	ENPP2
ENSG00000153012	55203	LGI2
ENSG00000179388	1960	EGR3
ENSG00000242247	26286	ARFGAP3

Causal Mechanistic Flows with Program Pr-117

ID	Mutation	Role	Regulator	Role	Regulon	# downstream regulons	# diffexp regulons	Drugs

CMFlow summary not available

Enrichment summary not available