Pr-109
Genes (176)
PFN2, MXI1, AMOT, FAM127A, BRE, RUSC1, CYB5R3, CERK, LIMK1, TESK1, CKAP4, UBTD1, HARS, NF2, AFAP1, GLTSCR1, CIC, SETD1A, GTPBP1, TNPO2, TBC1D13, MFN2, USP22, RERE, CAND2, ZMYM3, LSM14B, TAOK2, BLCAP, EIF4ENIF1, SLIT1, MYCBP2, CLCN6, RUNX1T1, PTPN4, RAPGEF4, TNRC6B, USP11, NEFM, ZMIZ1, DLG4, FRS3, CELSR2, RNF44, TSC1, APBB1, CAMTA1, NBEA, PLCB1, MNT, HUWE1, FHOD3, LRRC20, UBQLN2, ACACA, MAP1A, MAFG, AGPAT4, TTBK2, SYNE1, BRSK2, PEG3, RIMBP2, CHGB, FGF9, RALGPS1, PDPK1, ATP2B2, PPP1R9A, CAMK1D, KIAA0430, PPME1, PLXNA2, ZMYND8, DDX6, SV2C, HABP4, KATNB1, VPS53, FOXK2, SETBP1, DYRK1A, ST8SIA3, SUPT5H, ATXN2, SLC35E2, TBCD, CRKL, HIP1R, PKP4, DSCAM, SREBF2, CBFA2T2, CDH7, MYO9A, DEPDC5, RAPGEFL1, CLSTN3, TERF2IP, PLA2G6, USP7, PHACTR1, DLG3, CAMSAP1, CNNM2, WDR7, MGEA5, EHD3, FBXW7, PRDM2, DLGAP1, PFKP, MLF2, KLHL22, DNAL4, SYNGR1, KCTD17, ZC3H7B, AHSA1, PORCN, FBXL15, USP5, STK25, MEF2D, ABHD8, MGAT3, MAP1S, TUBGCP2, RAB15, TCF25, NDUFS2, ZMAT4, OTUB1, NDUFV1, SEZ6L2, CCDC85B, NIPSNAP1, OSBP2, C22orf29, NFKBIL1, AARSD1, OTUB2, HMOX2, AP2A2, NDUFA10, BNIP3, XYLT1, TRAK1, KIFAP3, NOLC1, HIRA, DHX30, MYH10, PELP1, SPATA2, RNF123, NUCKS1, DYNC1LI1, TMEM181, ZNF770, ZNF350, GAB2, MYH7, RAB2A, TSPAN14, SLC25A23, LATS1, AOC2, EFNA3, SLC1A7, PRKAA2, JRKL, CHUK, SGSM3, MKL1, GABBR2Regulons (31)
R-566, R-590, R-605, R-820, R-830, R-833, R-837, R-870, R-884, R-977, R-1031, R-1108, R-1186, R-1195, R-1206, R-1244, R-1371, R-1623, R-1783, R-2109, R-2128, R-2150, R-2376, R-2563, R-2871, R-2905, R-3165, R-3244, R-3252, R-3299, R-3536Regulons in program Pr-109
| Regulon | Cox Hazard Ratio | # genes | # causal flows |
|---|---|---|---|
| R-566 | -2.29193 | 6 | 8 |
| R-590 | 0.74794 | 9 | 4 |
| R-605 | 0.120998 | 16 | 3 |
| R-820 | -0.84843 | 18 | 3 |
| R-830 | -1.03201 | 6 | 9 |
| R-833 | -1.02048 | 6 | 3 |
| R-837 | 0.275301 | 5 | 5 |
| R-870 | -0.790944 | 18 | 4 |
| R-884 | -1.04751 | 7 | 1 |
| R-977 | -1.11979 | 15 | 12 |
| R-1031 | -0.935181 | 5 | 16 |
| R-1108 | -1.11844 | 11 | 9 |
| R-1186 | -0.5724 | 17 | 7 |
| R-1195 | -0.777241 | 13 | 21 |
| R-1206 | 0.331229 | 8 | 3 |
| R-1244 | -2.01396 | 7 | 11 |
| R-1371 | -0.743689 | 34 | 6 |
| R-1623 | -0.399001 | 5 | 7 |
| R-1783 | -0.196812 | 6 | 5 |
| R-2109 | -1.12309 | 6 | 10 |
| R-2128 | 0.0884793 | 14 | 4 |
| R-2150 | 0.683218 | 7 | 2 |
| R-2376 | -1.23139 | 7 | 16 |
| R-2563 | -1.52195 | 7 | 2 |
| R-2871 | -1.23878 | 11 | 25 |
| R-2905 | -0.867589 | 7 | 7 |
| R-3165 | -3.68002 | 12 | 12 |
| R-3244 | -0.23067 | 13 | 8 |
| R-3252 | -0.818192 | 8 | 2 |
| R-3299 | -1.01593 | 5 | 3 |
| R-3536 | -0.548696 | 6 | 5 |
Genes in program Pr-109
Causal Mechanistic Flows with Program Pr-109
| ID | Mutation | Role | Regulator | Role | Regulon | # downstream regulons | # diffexp regulons | Drugs |
|---|
CMFlow summary not available
Enrichment summary not available