Program – gbmMINER Portal

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Program – gbmMINER Portal

Program

Program Pr-102

Genes (40)

IFNGR1, MGAT4A, SEL1L, CREM, CD69, GIMAP6, ITGAX, IRF8, HHEX, DCN, FKBP1A, SNAP23, TFEC, LRMP, KCNJ5, GMFG, PRKAA1, FAM105A, SMPDL3A, KCTD12, FCGRT, SNX6, CLEC4A, TM6SF1, PLA2G7, ARHGAP25, CETP, PDGFB, NR5A2, CTGF, MYCT1, PTPRB, HIGD1B, TBC1D4, ACVRL1, FLI1, TAL1, FZD4, PCCA, WWTR1

Regulons (15)

R-237, R-261, R-279, R-329, R-421, R-1328, R-1803, R-2081, R-2211, R-2591, R-2910, R-2942, R-2966, R-3447, R-3581

Regulons in program Pr-102

Regulon	Cox Hazard Ratio	# genes	# causal flows
R-237	0.844426	9	10
R-261	1.0632	15	7
R-279	1.21976	11	7
R-329	1.39259	15	24
R-421	1.09493	20	38
R-1328	0.720984	7	7
R-1803	-1.68802	13	10
R-2081	1.02267	9	5
R-2211	1.10066	14	5
R-2591	1.20871	17	30
R-2910	1.23995	12	7
R-2942	1.52535	17	50
R-2966	1.20451	9	9
R-3447	1.00392	11	4
R-3581	1.26731	10	3

Genes in program Pr-102

EnsEMBL Id	Entrez Id	Preferred
ENSG00000027697	3459	IFNGR1
ENSG00000071073	11320	MGAT4A
ENSG00000071537	6400	SEL1L
ENSG00000095794	1390	CREM
ENSG00000110848	969	CD69
ENSG00000133561	474344	GIMAP6
ENSG00000140678	3687	ITGAX
ENSG00000140968	3394	IRF8
ENSG00000152804	3087	HHEX
ENSG00000011465	1634	DCN
ENSG00000088832	2280	FKBP1A
ENSG00000092531	8773	SNAP23
ENSG00000105967	22797	TFEC
ENSG00000118308	4033	LRMP
ENSG00000120457	3762	KCNJ5
ENSG00000130755	9535	GMFG
ENSG00000132356	5562	PRKAA1
ENSG00000145569	54491	FAM105A
ENSG00000172594	10924	SMPDL3A
ENSG00000178695	115207	KCTD12
ENSG00000104870	2217	FCGRT
ENSG00000129515	58533	SNX6
ENSG00000111729	50856	CLEC4A
ENSG00000136404	53346	TM6SF1
ENSG00000146070	7941	PLA2G7
ENSG00000163219	9938	ARHGAP25
ENSG00000087237	1071	CETP
ENSG00000100311	5155	PDGFB
ENSG00000116833	2494	NR5A2
ENSG00000118523	1490	CTGF
ENSG00000120279	80177	MYCT1
ENSG00000127329	5787	PTPRB
ENSG00000131097	51751	HIGD1B
ENSG00000136111	9882	TBC1D4
ENSG00000139567	94	ACVRL1
ENSG00000151702	2313	FLI1
ENSG00000162367	6886	TAL1
ENSG00000174804	8322	FZD4
ENSG00000175198	5095	PCCA
ENSG00000018408	25937	WWTR1

Causal Mechanistic Flows with Program Pr-102

ID	Mutation	Role	Regulator	Role	Regulon	# downstream regulons	# diffexp regulons	Drugs

CMFlow summary not available

Enrichment summary not available