| CMF-18273 | MEGF8 | up-regulates | IRF9 | activates | R-1447 | 15 | 3 | Drugs (2) |
| CMF-18274 | MEGF8 | up-regulates | IRF9 | activates | R-1446 | 15 | 3 | Drugs (12) Regulator Drugs (0)Regulon Drugs (12)OPROZOMIB, IXAZOMIB, MARIZOMIB, NIVOCASAN, BORTEZOMIB, EMRICASAN, EMAPUNIL, BELNACASAN, IXAZOMIB CITRATE, ALEMTUZUMAB, ONO-2952, CARFILZOMIB |
| CMF-18275 | MEGF8 | up-regulates | IRF9 | activates | R-1451 | 15 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-18278 | MEGF8 | up-regulates | IRF2 | activates | R-416 | 25 | 2 | Drugs (10) |
| CMF-18279 | MEGF8 | up-regulates | IRF2 | activates | R-424 | 25 | 2 | Drugs (4) |
| CMF-18281 | MEGF8 | up-regulates | NFKB1 | activates | R-294 | 25 | 2 | Drugs (5) |
| CMF-18289 | MEGF8 | down-regulates | POU4F1 | represses | R-2762 | 11 | 3 | Drugs (2) |
| CMF-18290 | MEGF8 | down-regulates | POU4F1 | represses | R-2763 | 11 | 3 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)ASK-8007 |
| CMF-18291 | MEGF8 | down-regulates | POU4F1 | activates | R-2764 | 11 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-18292 | MEGF8 | up-regulates | EGR1 | activates | R-991 | 20 | 2 | Drugs (9) |
| CMF-18293 | MEGF8 | up-regulates | EGR1 | activates | R-1005 | 20 | 2 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-18294 | MEGF8 | down-regulates | SIX6 | represses | R-3176 | 4 | 1 | Drugs (4) |
| CMF-18297 | MEGF8 | down-regulates | LHX3 | represses | R-1995 | 24 | 3 | Drugs (6) |
| CMF-18298 | MEGF8 | down-regulates | LHX3 | represses | R-2007 | 24 | 3 | Drugs (4) |
| CMF-18302 | MEGF8 | down-regulates | GATA6 | represses | R-1248 | 18 | 1 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)GSK-1995057, PRAMLINTIDE, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, VARESPLADIB METHYL, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, PRAMLINTIDE ACETATE, TOPIRAMATE, VANTICTUMAB, ACETAZOLAMIDE SODIUM, POLMACOXIB, DAVALINTIDE |
| CMF-18307 | MEGF8 | up-regulates | FOS | activates | R-3402 | 6 | 1 | Drugs (58) Regulator Drugs (0)Regulon Drugs (58)ERIBULIN MESYLATE, SAGOPILONE, AGS-16C3F, TELISOTUZUMAB VEDOTIN, DOCETAXEL, FOSBRETABULIN DISODIUM, VINCRISTINE, VINFLUNINE, LEXIBULIN, VINCRISTINE SULFATE, TRASTUZUMAB EMTANSINE, ENFORTUMAB VEDOTIN, VINORELBINE TARTRATE, LIFASTUZUMAB VEDOTIN, KOS-1584, PRALUZATAMAB RAVTANSINE, LADIRATUZUMAB VEDOTIN, PACLITAXEL, CROLIBULIN, PACLITAXEL POLIGLUMEX, PATUPILONE, ASG-5ME, ANG1005, PINATUZUMAB VEDOTIN, VERUBULIN, VINBLASTINE SULFATE, VINORELBINE, DAVUNETIDE, BELANTAMAB MAFODOTIN, FOSBRETABULIN, ABT-751, MIRVETUXIMAB SORAVTANSINE, IXABEPILONE, POLATUZUMAB VEDOTIN, T-900607, APRUTUMAB IXADOTIN, PLINABULIN, TISOTUMAB VEDOTIN, DOLASTATIN-10, FOSBRETABULIN TROMETHAMINE, SAR-408701, CABAZITAXEL, PACLITAXEL DOCOSAHEXAENOIC ACID, ERIBULIN, BMS-275183, INDUSATUMAB VEDOTIN, GLEMBATUMUMAB VEDOTIN, COLCHICINE, VANDORTUZUMAB VEDOTIN, VINBLASTINE, BRENTUXIMAB VEDOTIN, EPOTHILONE D, SOFITUZUMAB VEDOTIN, INDIBULIN, AZINTUXIZUMAB VEDOTIN, LAROTAXEL, RG-7841, LORVOTUZUMAB MERTANSINE |
| CMF-18309 | MEGF8 | down-regulates | PBX1 | represses | R-3161 | 12 | 3 | Drugs (7) |
| CMF-18310 | MEGF8 | down-regulates | PBX1 | represses | R-3166 | 12 | 3 | Drugs (4) |
| CMF-18315 | MEGF8 | down-regulates | MNX1 | activates | R-2261 | 4 | 1 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-18318 | MEGF8 | up-regulates | CEBPB | activates | R-1300 | 23 | 5 | Drugs (11) Regulator Drugs (0)Regulon Drugs (11)ATN-161, DAVANAT, CINTREDEKIN BESUDOTOX, NIVOCASAN, NATALIZUMAB, FIRATEGRAST, EMRICASAN, VOLOCIXIMAB, RECOMBINANT HUMAN INTERLEUKIN-15, PEGINTERFERON LAMBDA-1A, ABITUZUMAB |
| CMF-18320 | MEGF8 | up-regulates | CEBPB | activates | R-1305 | 23 | 5 | Drugs (5) |
| CMF-18321 | MEGF8 | up-regulates | CEBPB | activates | R-1304 | 23 | 5 | Drugs (6) |
| CMF-18325 | MEGF8 | up-regulates | BACH1 | activates | R-2746 | 11 | 3 | Drugs (3) |
| CMF-18327 | MEGF8 | down-regulates | NR0B1 | represses | R-2533 | 3 | 1 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-39092 | MEGF8 | down-regulates | hsa-mir-19b | represses | R-2953 | 1 | 1 | Drugs (4) |
| CMF-39093 | MEGF8 | down-regulates | hsa-mir-93 | represses | R-2412 | 44 | 4 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-39094 | MEGF8 | down-regulates | hsa-mir-93 | represses | R-2767 | 44 | 4 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL |
| CMF-39095 | MEGF8 | down-regulates | hsa-mir-93 | represses | R-3134 | 44 | 4 | Drugs (1) |
| CMF-39096 | MEGF8 | down-regulates | hsa-mir-93 | represses | R-3348 | 44 | 4 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)EMRICASAN |