Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

USP6NL - USP6 N-terminal like

Function

Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
9712 ENSG00000148429 USP6NL Q92738

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1566Pr-59116
R-1706Pr-59119
R-1788Pr-59114
R-2844Pr-59116
R-3460Pr-59114
R-548Pr-59115
R-627Pr-59118