Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

TRIP6 - thyroid hormone receptor interactor 6

Function

Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
7205 ENSG00000087077 TRIP6 Q15654

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1183Pr-431126
R-1248Pr-851119
R-1771Pr-43111
R-1802Pr-851114
R-1807Pr-201122
R-1848Pr-43118
R-1883Pr-43117
R-1900Pr-43117
R-1924Pr-43113
R-1937Pr-851112
R-1962Pr-851113
R-1994Pr-431124
R-647Pr-431115
R-666Pr-431120
R-821Pr-201110