Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

TPP1 - tripeptidyl peptidase 1

Function

Lysosomal serine protease with tripeptidyl-peptidase I activity (PubMed:11054422, PubMed:19038966, PubMed:19038967). May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases (PubMed:11054422, PubMed:19038966, PubMed:19038967). Requires substrates with an unsubstituted N-terminus (PubMed:19038966).

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
1200 ENSG00000166340 TPP1 O14773

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-215Pr-140115
R-2620Pr-1113
R-2749Pr-101112
R-3213Pr-137115
R-572Pr-1421139
R-646Pr-1401151