Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot
and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser
is available.
SRI - sorcin
Function
Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels.
Uniprot BrowserEntrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
---|---|---|---|
6717 | ENSG00000075142 | SRI | P30626 |
Gene Regulons
List of regulons containing the gene.
A gene
can be associated with multiple causal flows
as a member of multiple regulons
Regulon | Program | # genes | # regulators | # causal flows |
---|---|---|---|---|
R-1400 | Pr-85 | 1 | 1 | 8 |
R-1408 | Pr-85 | 1 | 1 | 7 |
R-1784 | Pr-43 | 1 | 1 | 11 |
R-1802 | Pr-85 | 1 | 1 | 14 |
R-1812 | Pr-43 | 1 | 1 | 5 |
R-1828 | Pr-43 | 1 | 1 | 11 |
R-1848 | Pr-43 | 1 | 1 | 8 |
R-1874 | Pr-20 | 1 | 1 | 7 |
R-1883 | Pr-43 | 1 | 1 | 7 |
R-1900 | Pr-43 | 1 | 1 | 7 |
R-1924 | Pr-43 | 1 | 1 | 3 |
R-1937 | Pr-85 | 1 | 1 | 12 |
R-1942 | Pr-43 | 1 | 1 | 12 |
R-1950 | Pr-43 | 1 | 1 | 45 |
R-1994 | Pr-43 | 1 | 1 | 24 |
R-2020 | Pr-20 | 1 | 1 | 33 |
R-292 | Pr-43 | 1 | 1 | 21 |
R-647 | Pr-43 | 1 | 1 | 15 |