Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

SLC22A4 - solute carrier family 22 member 4

Function

Sodium-ion dependent transporter of various organic cationic compounds. A key substrate of this transporter is ergothioneine (ET) (PubMed:15795384). Able to transport carnitine, probably moving one sodium ion with one molecule of carnitine. Also transports tetraethylammonium (TEA) without the involvement of sodium. May also contribute to regulate the transport of cationic compounds in testis across the blood-testis-barrier (PubMed:35307651).

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
6583 ENSG00000197208 SLC22A4 Q9H015

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1447Pr-22113
R-2478Pr-22118
R-2656Pr-711115
R-2945Pr-221142
R-3423Pr-172118