Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

SH2D4A - SH2 domain containing 4A

Function

Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
63898 ENSG00000104611 SH2D4A Q9H788

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1013Pr-121110
R-1484Pr-1551117
R-2451Pr-1311168
R-2475Pr-1551110
R-2538Pr-155119
R-996Pr-1551113