Gene – gbmMINER Portal

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Gene – gbmMINER Portal

Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

RTN4 - reticulon 4

Function

Isoform CRegulates cardiomyocyte apoptosis upon hypoxic conditions (By similarity). With isoform B, inhibits BACE1 activity and amyloid precursor protein processing (PubMed:16965550).

Uniprot Browser

Entrez ID	EnsEMBL ID	Preferred Name	Uniprot ID
57142	ENSG00000115310	RTN4	Q9NQC3

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

Regulon	Program	# genes	# regulators	# causal flows