Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot
and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser
is available.
PPP1R13B - protein phosphatase 1 regulatory subunit 13B
Function
Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53 (PubMed:11684014, PubMed:12524540). Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo.
Uniprot BrowserEntrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
---|---|---|---|
23368 | ENSG00000088808 | PPP1R13B | Q96KQ4 |
Gene Regulons
List of regulons containing the gene.
A gene
can be associated with multiple causal flows
as a member of multiple regulons