Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

PPP1R13B - protein phosphatase 1 regulatory subunit 13B

Function

Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53 (PubMed:11684014, PubMed:12524540). Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
23368 ENSG00000088808 PPP1R13B Q96KQ4

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1370Pr-1081112
R-598Pr-108116