Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

PHIP - pleckstrin homology domain interacting protein

Function

Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
55023 ENSG00000146247 PHIP Q8WWQ0

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1147Pr-581112
R-1167Pr-58116
R-1528Pr-58113
R-1600Pr-58117
R-1632Pr-58119
R-1682Pr-581117
R-1792Pr-58111
R-2757Pr-581119
R-2891Pr-58115
R-3225Pr-58114
R-3462Pr-581112
R-723Pr-581114