Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
MID1 - midline 1
Function
Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 4281 | ENSG00000101871 | MID1 | O15344 |
Gene Regulons
List of regulons containing the gene.
A gene can be associated with multiple causal flows as a member of multiple regulons
| Regulon | Program | # genes | # regulators | # causal flows |
|---|---|---|---|---|
| R-1129 | Pr-39 | 1 | 1 | 15 |
| R-1166 | Pr-39 | 1 | 1 | 12 |
| R-121 | Pr-39 | 1 | 1 | 9 |
| R-1225 | Pr-39 | 1 | 1 | 24 |
| R-1253 | Pr-39 | 1 | 1 | 28 |
| R-1490 | Pr-39 | 1 | 1 | 13 |
| R-1571 | Pr-39 | 1 | 1 | 14 |
| R-1597 | Pr-39 | 1 | 1 | 9 |
| R-1707 | Pr-39 | 1 | 1 | 14 |
| R-1790 | Pr-39 | 1 | 1 | 6 |
| R-2002 | Pr-177 | 1 | 1 | 23 |
| R-2289 | Pr-39 | 1 | 1 | 6 |
| R-2362 | Pr-39 | 1 | 1 | 9 |
| R-2399 | Pr-20 | 1 | 1 | 12 |
| R-2690 | Pr-39 | 1 | 1 | 13 |
| R-2722 | Pr-39 | 1 | 1 | 4 |
| R-2817 | Pr-39 | 1 | 1 | 10 |
| R-2845 | Pr-39 | 1 | 1 | 10 |
| R-2914 | Pr-39 | 1 | 1 | 14 |
| R-2929 | Pr-39 | 1 | 1 | 22 |
| R-2964 | Pr-39 | 1 | 1 | 26 |
| R-3056 | Pr-39 | 1 | 1 | 22 |
| R-3542 | Pr-39 | 1 | 1 | 7 |
| R-3602 | Pr-177 | 1 | 1 | 17 |
| R-3683 | Pr-39 | 1 | 1 | 20 |
| R-3697 | Pr-39 | 1 | 1 | 32 |
| R-649 | Pr-6 | 1 | 1 | 13 |
| R-702 | Pr-39 | 1 | 1 | 4 |