Gene – gbmMINER Portal

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Gene – gbmMINER Portal

Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

GZMM - granzyme M

Function

Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.

Uniprot Browser

Entrez ID	EnsEMBL ID	Preferred Name	Uniprot ID
3004	ENSG00000197540	GZMM	P51124

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

Regulon	Program	# genes	# regulators	# causal flows