Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

FRMD4A - FERM domain containing 4A

Function

Scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex (By similarity). Plays a redundant role with FRMD4B in epithelial polarization (By similarity). May regulate MAPT secretion by activating ARF6-signaling (PubMed:27044754).

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
55691 ENSG00000151474 FRMD4A Q9P2Q2

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1105Pr-58118
R-1227Pr-58114
R-1600Pr-58117
R-1632Pr-58119
R-1682Pr-581117
R-2757Pr-581119
R-2891Pr-58115
R-3462Pr-581112
R-723Pr-581114