Gene – gbmMINER Portal

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Gene – gbmMINER Portal

Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

COTL1 - coactosin like F-actin binding protein 1

Function

Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis.

Uniprot Browser

Entrez ID	EnsEMBL ID	Preferred Name	Uniprot ID
23406	ENSG00000103187	COTL1	Q14019

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

Regulon	Program	# genes	# regulators	# causal flows