Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

COL3A1 - collagen type III alpha 1 chain

Function

Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
1281 ENSG00000168542 COL3A1 P02461

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1256Pr-91134
R-1425Pr-10117
R-2115Pr-9115
R-2122Pr-10118
R-231Pr-101111
R-2512Pr-101110
R-2705Pr-91114
R-3603Pr-91134