| CMF-24418 | SEMA3C | down-regulates | ELK1 | activates | R-2145 | 12 | 3 | Drugs (1) |
| CMF-24421 | SEMA3C | down-regulates | STAT3 | activates | R-1535 | 25 | 9 | Drugs (12) Regulator Drugs (0)Regulon Drugs (12)INTERFERON BETA-1B, ANIFROLUMAB, INTERFERON ALFA-2A, INTERFERON ALFA-2B, PEGINTERFERON ALFA-2B, INTERFERON ALFA-N3, ALBINTERFERON ALFA-2B, INTERFERON ALFACON-1, ROPEGINTERFERON ALFA-2B, PEGINTERFERON ALFA-2A, PEGINTERFERON BETA-1A, INTERFERON BETA-1A |
| CMF-24423 | SEMA3C | down-regulates | STAT3 | activates | R-1525 | 25 | 9 | Drugs (4) |
| CMF-24426 | SEMA3C | down-regulates | STAT3 | activates | R-1521 | 25 | 9 | Drugs (6) |
| CMF-24427 | SEMA3C | down-regulates | STAT3 | activates | R-1532 | 25 | 9 | Drugs (1) |
| CMF-24429 | SEMA3C | down-regulates | IRF2 | activates | R-415 | 25 | 7 | Drugs (8) |
| CMF-24430 | SEMA3C | down-regulates | IRF2 | activates | R-431 | 25 | 7 | Drugs (1) |
| CMF-24431 | SEMA3C | down-regulates | IRF2 | activates | R-426 | 25 | 7 | Drugs (11) Regulator Drugs (0)Regulon Drugs (11)AMG-780, MEDI-3617, ENIBARCIMAB, F16SIP 131I, TREBANANIB, F16IL2, VANUCIZUMAB, PROBUCOL, FARICIMAB, CVX-060, NESVACUMAB |
| CMF-24435 | SEMA3C | down-regulates | IRF2 | activates | R-424 | 25 | 7 | Drugs (4) |
| CMF-24436 | SEMA3C | down-regulates | ARID5B | activates | R-3006 | 4 | 1 | Drugs (33) Regulator Drugs (0)Regulon Drugs (33)SAVOLITINIB, TELISOTUZUMAB VEDOTIN, AMUVATINIB, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, MK-8033, AMG-337, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, JNJ-38877605, GLESATINIB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, GOLVATINIB |
| CMF-24437 | SEMA3C | down-regulates | ZBTB16 | activates | R-2185 | 16 | 2 | Drugs (4) |
| CMF-24440 | SEMA3C | down-regulates | NFKB1 | activates | R-302 | 25 | 6 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24441 | SEMA3C | down-regulates | NFKB1 | activates | R-300 | 25 | 6 | Drugs (23) Regulator Drugs (0)Regulon Drugs (23)TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE |
| CMF-24444 | SEMA3C | down-regulates | NFKB1 | activates | R-292 | 25 | 6 | Drugs (20) Regulator Drugs (0)Regulon Drugs (20)GSK-1995057, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, EPELSIBAN, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, OXYTOCIN, CARBETOCIN, NOLASIBAN, TOPIRAMATE, VANTICTUMAB, ATOSIBAN, FE 202767, BARUSIBAN, ACETAZOLAMIDE SODIUM, POLMACOXIB, RETOSIBAN |
| CMF-24449 | SEMA3C | up-regulates | FOXL1 | represses | R-1848 | 25 | 9 | Drugs (110) Regulator Drugs (0)Regulon Drugs (110)CISATRACURIUM, PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, GSK-1995057, RUPATADINE, DOXYLAMINE SUCCINATE, CISATRACURIUM BESYLATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, SUXAMETHONIUM, PRAMLINTIDE, CYPROHEPTADINE HYDROCHLORIDE, BRINZOLAMIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, MIVACURIUM, EBASTINE, SULTHIAME, CINNARIZINE, HYDROXYZINE, LORATADINE, DORZOLAMIDE, LY2624803, ROCURONIUM BROMIDE, PHENIRAMINE MALEATE, ACETAZOLAMIDE, TRIPROLIDINE HYDROCHLORIDE, METHAZOLAMIDE, MIVACURIUM CHLORIDE, PRAMLINTIDE ACETATE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, TISOTUMAB VEDOTIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, TOPIRAMATE, VANTICTUMAB, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, ACETAZOLAMIDE SODIUM, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, POLMACOXIB, ROCURONIUM, CETIRIZINE, METHDILAZINE, DAVALINTIDE |
| CMF-24451 | SEMA3C | up-regulates | FOXL1 | represses | R-1853 | 25 | 9 | Drugs (8) |
| CMF-24454 | SEMA3C | down-regulates | FOXO1 | activates | R-709 | 21 | 10 | Drugs (1) |
| CMF-24455 | SEMA3C | down-regulates | FOXO1 | activates | R-704 | 21 | 10 | Drugs (24) Regulator Drugs (0)Regulon Drugs (24)TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE |
| CMF-24456 | SEMA3C | down-regulates | FOXO1 | activates | R-708 | 21 | 10 | Drugs (45) Regulator Drugs (0)Regulon Drugs (45)PF-04691502, POZIOTINIB, DEXTROTHYROXINE, BGT-226, SONOLISIB, VOXTALISIB, CANERTINIB DIHYDROCHLORIDE, NERATINIB MALEATE, APITOLISIB, DS-7423, NERATINIB, BMS-690514, AC-480, PAXALISIB, PICTILISIB, LIOTHYRONINE, DEXTROTHYROXINE SODIUM, DACOMITINIB, KBP5209, TARLOXOTINIB, VS-5584, VALPROIC ACID, SAMOTOLISIB, VANDETANIB, DACTOLISIB, DIVALPROEX SODIUM, GNF-Pf-5468, WX-037, CANERTINIB, PILARALISIB, TASELISIB, JNJ-26483327, LEVOTHYROXINE SODIUM, GEDATOLISIB, OMIPALISIB, AFATINIB DIMALEATE, AFATINIB, LIOTHYRONINE SODIUM, VALPROATE SODIUM, LEVOTHYROXINE, PA-799, GSK-1059615, BUPARLISIB, SF-1126, PANULISIB |
| CMF-24458 | SEMA3C | down-regulates | FOXO1 | activates | R-710 | 21 | 10 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24462 | SEMA3C | down-regulates | FOXO1 | activates | R-698 | 21 | 10 | Drugs (94) Regulator Drugs (0)Regulon Drugs (94)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, RUPATADINE, DOXYLAMINE SUCCINATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, IMSIDOLIMAB, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, EBASTINE, CINNARIZINE, OLECLUMAB, HYDROXYZINE, LORATADINE, LY2624803, BELZUTIFAN, PHENIRAMINE MALEATE, TRIPROLIDINE HYDROCHLORIDE, NERAMEXANE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, NERAMEXANE MESYLATE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, OCRIPLASMIN, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, CETIRIZINE, SPESOLIMAB, METHDILAZINE |
| CMF-24463 | SEMA3C | down-regulates | FOXO1 | activates | R-702 | 21 | 10 | Drugs (20) Regulator Drugs (0)Regulon Drugs (20)BEVACIZUMAB, CONBERCEPT, AMG-780, MEDI-3617, PEGAPTANIB SODIUM, ENIBARCIMAB, F16SIP 131I, TREBANANIB, PEGAPTANIB OCTASODIUM, MUPARFOSTAT, F16IL2, VANUCIZUMAB, PROBUCOL, RANIBIZUMAB, FARICIMAB, CVX-060, ABICIPAR PEGOL, NESVACUMAB, AFLIBERCEPT, BROLUCIZUMAB |
| CMF-24464 | SEMA3C | down-regulates | RORA | activates | R-1944 | 8 | 5 | Drugs (87) Regulator Drugs (0)Regulon Drugs (87)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, RUPATADINE, DOXYLAMINE SUCCINATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, EBASTINE, CINNARIZINE, HYDROXYZINE, LORATADINE, LY2624803, PHENIRAMINE MALEATE, TRIPROLIDINE HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, CETIRIZINE, METHDILAZINE |
| CMF-24466 | SEMA3C | down-regulates | RORA | activates | R-1945 | 8 | 5 | Drugs (7) |
| CMF-24467 | SEMA3C | down-regulates | RORA | activates | R-1942 | 8 | 5 | Drugs (106) Regulator Drugs (0)Regulon Drugs (106)CISATRACURIUM, PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, RUPATADINE, DOXYLAMINE SUCCINATE, CISATRACURIUM BESYLATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, SUXAMETHONIUM, CYPROHEPTADINE HYDROCHLORIDE, BRINZOLAMIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, MIVACURIUM, EBASTINE, SULTHIAME, CINNARIZINE, VARESPLADIB METHYL, HYDROXYZINE, LORATADINE, DORZOLAMIDE, LY2624803, ROCURONIUM BROMIDE, PHENIRAMINE MALEATE, ACETAZOLAMIDE, TRIPROLIDINE HYDROCHLORIDE, METHAZOLAMIDE, MIVACURIUM CHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, TOPIRAMATE, VANTICTUMAB, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, ACETAZOLAMIDE SODIUM, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, POLMACOXIB, ROCURONIUM, CETIRIZINE, METHDILAZINE |
| CMF-24468 | SEMA3C | down-regulates | RORA | activates | R-1949 | 8 | 5 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24469 | SEMA3C | up-regulates | FEV | represses | R-3030 | 5 | 3 | Drugs (71) Regulator Drugs (0)Regulon Drugs (71)ESTROGENS, ESTERIFIED, SAVOLITINIB, TELISOTUZUMAB VEDOTIN, ATN-161, RALOXIFENE, PRINABEREL, LASOFOXIFENE, AMUVATINIB, BAZEDOXIFENE ACETATE, CHLOROTRIANISENE, ESTRIOL, BIRINAPANT, ACOLBIFENE, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, SYNTHETIC CONJUGATED ESTROGENS, B, OSPEMIFENE, TEPOTINIB HYDROCHLORIDE, TOREMIFENE CITRATE, FORETINIB, RALOXIFENE HYDROCHLORIDE, ONARTUZUMAB, SAR-125844, ERTEBEREL, AMG-208, FULVESTRANT, CILENGITIDE, TIROFIBAN HYDROCHLORIDE, ESTROGENS, CONJUGATED SYNTHETIC A, ESTROGENS, CONJUGATED, MK-8033, FISPEMIFENE, AMG-337, ABCIXIMAB, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, AFIMOXIFENE, MK-2461, MERESTINIB, DIETHYLSTILBESTROL DIPHOSPHATE, BMS-777607, BAZEDOXIFENE, CAPMATINIB, ETARACIZUMAB, JNJ-38877605, GLESATINIB, INTETUMUMAB, BMS-817378, CABOZANTINIB S-MALATE, MF101, AUS-131, CRIZOTINIB, TOREMIFENE, EMD-1204831, TIVANTINIB, ESTRAMUSTINE PHOSPHATE, NEDOSIRAN SODIUM, TELISOTUZUMAB, ESTETROL, TEPOTINIB, EMIBETUZUMAB, BPI-9016, ESTRAMUSTINE PHOSPHATE SODIUM, PF-04217903, ARZOXIFENE, EPTIFIBATIDE, ABITUZUMAB, GOLVATINIB, TIROFIBAN |
| CMF-24470 | SEMA3C | up-regulates | FEV | represses | R-3033 | 5 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24471 | SEMA3C | up-regulates | FEV | represses | R-3031 | 5 | 3 | Drugs (2) |
| CMF-24472 | SEMA3C | up-regulates | TAL1 | represses | R-320 | 11 | 5 | Drugs (11) Regulator Drugs (0)Regulon Drugs (11)BEVACIZUMAB, CONBERCEPT, PEGAPTANIB SODIUM, PEGAPTANIB OCTASODIUM, MUPARFOSTAT, VANUCIZUMAB, RANIBIZUMAB, FARICIMAB, ABICIPAR PEGOL, AFLIBERCEPT, BROLUCIZUMAB |
| CMF-24475 | SEMA3C | up-regulates | TAL1 | represses | R-322 | 11 | 5 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24476 | SEMA3C | down-regulates | BCL6 | activates | R-629 | 23 | 12 | Drugs (24) Regulator Drugs (0)Regulon Drugs (24)TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE |
| CMF-24477 | SEMA3C | down-regulates | BCL6 | activates | R-626 | 23 | 12 | Drugs (8) |
| CMF-24483 | SEMA3C | down-regulates | BCL6 | activates | R-622 | 23 | 12 | Drugs (71) Regulator Drugs (0)Regulon Drugs (71)ESTROGENS, ESTERIFIED, SAVOLITINIB, TELISOTUZUMAB VEDOTIN, ATN-161, RALOXIFENE, PRINABEREL, LASOFOXIFENE, AMUVATINIB, BAZEDOXIFENE ACETATE, CHLOROTRIANISENE, ESTRIOL, BIRINAPANT, ACOLBIFENE, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, SYNTHETIC CONJUGATED ESTROGENS, B, OSPEMIFENE, TEPOTINIB HYDROCHLORIDE, TOREMIFENE CITRATE, FORETINIB, RALOXIFENE HYDROCHLORIDE, ONARTUZUMAB, SAR-125844, ERTEBEREL, AMG-208, FULVESTRANT, CILENGITIDE, TIROFIBAN HYDROCHLORIDE, ESTROGENS, CONJUGATED SYNTHETIC A, ESTROGENS, CONJUGATED, MK-8033, FISPEMIFENE, AMG-337, ABCIXIMAB, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, AFIMOXIFENE, MK-2461, MERESTINIB, DIETHYLSTILBESTROL DIPHOSPHATE, BMS-777607, BAZEDOXIFENE, CAPMATINIB, ETARACIZUMAB, JNJ-38877605, GLESATINIB, INTETUMUMAB, BMS-817378, CABOZANTINIB S-MALATE, MF101, AUS-131, CRIZOTINIB, TOREMIFENE, EMD-1204831, TIVANTINIB, ESTRAMUSTINE PHOSPHATE, NEDOSIRAN SODIUM, TELISOTUZUMAB, ESTETROL, TEPOTINIB, EMIBETUZUMAB, BPI-9016, ESTRAMUSTINE PHOSPHATE SODIUM, PF-04217903, ARZOXIFENE, EPTIFIBATIDE, ABITUZUMAB, GOLVATINIB, TIROFIBAN |
| CMF-24484 | SEMA3C | down-regulates | BCL6 | activates | R-632 | 23 | 12 | Drugs (8) |
| CMF-24485 | SEMA3C | down-regulates | BCL6 | activates | R-635 | 23 | 12 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |
| CMF-24489 | SEMA3C | down-regulates | ESRRG | activates | R-2734 | 7 | 3 | Drugs (4) |
| CMF-24492 | SEMA3C | up-regulates | HOXD9 | represses | R-1671 | 5 | 2 | Drugs (1) |
| CMF-24495 | SEMA3C | down-regulates | FOSL1 | activates | R-1985 | 12 | 7 | Drugs (4) |
| CMF-24496 | SEMA3C | down-regulates | FOSL1 | activates | R-1993 | 12 | 7 | Drugs (58) Regulator Drugs (0)Regulon Drugs (58)ERIBULIN MESYLATE, SAGOPILONE, AGS-16C3F, TELISOTUZUMAB VEDOTIN, DOCETAXEL, FOSBRETABULIN DISODIUM, VINCRISTINE, VINFLUNINE, LEXIBULIN, VINCRISTINE SULFATE, TRASTUZUMAB EMTANSINE, ENFORTUMAB VEDOTIN, VINORELBINE TARTRATE, LIFASTUZUMAB VEDOTIN, KOS-1584, PRALUZATAMAB RAVTANSINE, LADIRATUZUMAB VEDOTIN, PACLITAXEL, CROLIBULIN, PACLITAXEL POLIGLUMEX, PATUPILONE, ASG-5ME, ANG1005, PINATUZUMAB VEDOTIN, VERUBULIN, VINBLASTINE SULFATE, VINORELBINE, DAVUNETIDE, BELANTAMAB MAFODOTIN, FOSBRETABULIN, ABT-751, MIRVETUXIMAB SORAVTANSINE, IXABEPILONE, POLATUZUMAB VEDOTIN, T-900607, APRUTUMAB IXADOTIN, PLINABULIN, TISOTUMAB VEDOTIN, DOLASTATIN-10, FOSBRETABULIN TROMETHAMINE, SAR-408701, CABAZITAXEL, PACLITAXEL DOCOSAHEXAENOIC ACID, ERIBULIN, BMS-275183, INDUSATUMAB VEDOTIN, GLEMBATUMUMAB VEDOTIN, COLCHICINE, VANDORTUZUMAB VEDOTIN, VINBLASTINE, BRENTUXIMAB VEDOTIN, EPOTHILONE D, SOFITUZUMAB VEDOTIN, INDIBULIN, AZINTUXIZUMAB VEDOTIN, LAROTAXEL, RG-7841, LORVOTUZUMAB MERTANSINE |
| CMF-24497 | SEMA3C | down-regulates | FOSL1 | activates | R-1983 | 12 | 7 | Drugs (94) Regulator Drugs (0)Regulon Drugs (94)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, GSK-1995057, RUPATADINE, DOXYLAMINE SUCCINATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, DICHLORPHENAMIDE, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, EBASTINE, SULTHIAME, CINNARIZINE, HYDROXYZINE, LORATADINE, LY2624803, PHENIRAMINE MALEATE, ACETAZOLAMIDE, TRIPROLIDINE HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, TISOTUMAB VEDOTIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, VANTICTUMAB, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, ACETAZOLAMIDE SODIUM, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, CETIRIZINE, METHDILAZINE |
| CMF-24498 | SEMA3C | down-regulates | FOSL1 | activates | R-1982 | 12 | 7 | Drugs (3) |
| CMF-24500 | SEMA3C | down-regulates | FOSL1 | activates | R-1992 | 12 | 7 | Drugs (3) |
| CMF-24502 | SEMA3C | down-regulates | SMAD3 | activates | R-2543 | 15 | 6 | Drugs (7) |
| CMF-24503 | SEMA3C | down-regulates | SMAD3 | activates | R-2546 | 15 | 6 | Drugs (1) |
| CMF-24505 | SEMA3C | down-regulates | SMAD3 | activates | R-2550 | 15 | 6 | Drugs (1) |
| CMF-24506 | SEMA3C | down-regulates | SMAD3 | activates | R-2549 | 15 | 6 | Drugs (3) |
| CMF-24507 | SEMA3C | down-regulates | SMAD3 | activates | R-2538 | 15 | 6 | Drugs (44) Regulator Drugs (0)Regulon Drugs (44)POZIOTINIB, MM-111, TRASTUZUMAB DERUXTECAN, VARLITINIB, CUDC-101, LAPATINIB DITOSYLATE, TUCATINIB, HEMAY-022, MP-412, TRASTUZUMAB EMTANSINE, ZENOCUTUZUMAB, CANERTINIB DIHYDROCHLORIDE, NERATINIB MALEATE, MUBRITINIB, LAPATINIB, SAPITINIB, NERATINIB, BMS-690514, AC-480, DACOMITINIB, KBP5209, TARLOXOTINIB, VANDETANIB, ALLITINIB, ERTUMAXOMAB, TRASTUZUMAB DUOCARMAZINE, MARGETUXIMAB, TRASTUZUMAB, T-DM1, CANERTINIB, BDTX189, JNJ-26483327, TESEVATINIB, JI-101, AFATINIB DIMALEATE, CP-724714, AFATINIB, TG100-801, AEE-788, PYROTINIB, TAK-285, PERTUZUMAB, GSK-690693, GANCOTAMAB |
| CMF-24509 | SEMA3C | down-regulates | ARID5A | activates | R-160 | 15 | 5 | Drugs (2) |
| CMF-24510 | SEMA3C | down-regulates | ARID5A | activates | R-159 | 15 | 5 | Drugs (3) |
| CMF-24512 | SEMA3C | down-regulates | ARID5A | activates | R-167 | 15 | 5 | Drugs (2) |
| CMF-24515 | SEMA3C | up-regulates | BARX2 | represses | R-1751 | 7 | 2 | Drugs (43) Regulator Drugs (0)Regulon Drugs (43)SAVOLITINIB, TELISOTUZUMAB VEDOTIN, ATN-161, AMUVATINIB, BIRINAPANT, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, CILENGITIDE, TIROFIBAN HYDROCHLORIDE, MK-8033, AMG-337, ABCIXIMAB, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, ETARACIZUMAB, JNJ-38877605, GLESATINIB, INTETUMUMAB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, EPTIFIBATIDE, ABITUZUMAB, GOLVATINIB, TIROFIBAN |
| CMF-24517 | SEMA3C | up-regulates | TP73 | represses | R-1962 | 1 | 1 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24518 | SEMA3C | down-regulates | HMGA2 | activates | R-3604 | 2 | 1 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)PROBUCOL |
| CMF-24520 | SEMA3C | down-regulates | NFE2L2 | activates | R-1381 | 10 | 5 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24523 | SEMA3C | up-regulates | GATA2 | represses | R-1802 | 4 | 2 | Drugs (14) Regulator Drugs (0)Regulon Drugs (14)GSK-1995057, PRAMLINTIDE, BRINZOLAMIDE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, SULTHIAME, DORZOLAMIDE, ACETAZOLAMIDE, METHAZOLAMIDE, PRAMLINTIDE ACETATE, TOPIRAMATE, ACETAZOLAMIDE SODIUM, POLMACOXIB, DAVALINTIDE |
| CMF-24529 | SEMA3C | up-regulates | NKX6-1 | represses | R-2845 | 20 | 8 | Drugs (19) Regulator Drugs (0)Regulon Drugs (19)BEVACIZUMAB, CONBERCEPT, AMG-780, MEDI-3617, PEGAPTANIB SODIUM, ENIBARCIMAB, F16SIP 131I, TREBANANIB, PEGAPTANIB OCTASODIUM, MUPARFOSTAT, F16IL2, VANUCIZUMAB, RANIBIZUMAB, FARICIMAB, CVX-060, ABICIPAR PEGOL, NESVACUMAB, AFLIBERCEPT, BROLUCIZUMAB |
| CMF-24530 | SEMA3C | up-regulates | NKX6-1 | represses | R-2852 | 20 | 8 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24531 | SEMA3C | up-regulates | NKX6-1 | represses | R-2843 | 20 | 8 | Drugs (2) |
| CMF-24532 | SEMA3C | up-regulates | NKX6-1 | represses | R-2849 | 20 | 8 | Drugs (16) Regulator Drugs (0)Regulon Drugs (16)PONEZUMAB, CRENEZUMAB, ELIGLUSTAT, GANTENERUMAB, SOLANEZUMAB, ELIGLUSTAT TARTRATE, MIGLUSTAT, BAPINEUZUMAB, GSK933776, SATRALIZUMAB, LUCERASTAT, ADUCANUMAB, TRAMIPROSATE, LECANEMAB, DONANEMAB, VANUTIDE CRIDIFICAR |
| CMF-24533 | SEMA3C | up-regulates | NKX6-1 | represses | R-2841 | 20 | 8 | Drugs (2) |
| CMF-24535 | SEMA3C | down-regulates | NR1H2 | activates | R-3606 | 4 | 1 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)ANG1005 |
| CMF-24538 | SEMA3C | up-regulates | CEBPE | represses | R-2671 | 13 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24540 | SEMA3C | up-regulates | CEBPE | represses | R-2670 | 13 | 3 | Drugs (5) |
| CMF-24546 | SEMA3C | up-regulates | ETS1 | represses | R-3416 | 3 | 2 | Drugs (2) |
| CMF-24547 | SEMA3C | down-regulates | RELA | activates | R-3149 | 3 | 1 | Drugs (2) |
| CMF-24549 | SEMA3C | up-regulates | E2F2 | represses | R-548 | 3 | 2 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24551 | SEMA3C | up-regulates | MYCN | represses | R-1807 | 5 | 2 | Drugs (5) |
| CMF-24555 | SEMA3C | down-regulates | ZNF148 | activates | R-821 | 23 | 6 | Drugs (104) Regulator Drugs (0)Regulon Drugs (104)CISATRACURIUM, PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, RUPATADINE, DOXYLAMINE SUCCINATE, CISATRACURIUM BESYLATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, SUXAMETHONIUM, CYPROHEPTADINE HYDROCHLORIDE, BRINZOLAMIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, DORZOLAMIDE HYDROCHLORIDE, DICHLORPHENAMIDE, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, MIVACURIUM, EBASTINE, SULTHIAME, CINNARIZINE, HYDROXYZINE, LORATADINE, DORZOLAMIDE, LY2624803, ROCURONIUM BROMIDE, PHENIRAMINE MALEATE, ACETAZOLAMIDE, TRIPROLIDINE HYDROCHLORIDE, METHAZOLAMIDE, MIVACURIUM CHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, TOPIRAMATE, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, ACETAZOLAMIDE SODIUM, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, POLMACOXIB, ROCURONIUM, CETIRIZINE, METHDILAZINE |
| CMF-24559 | SEMA3C | down-regulates | ZNF148 | activates | R-829 | 23 | 6 | Drugs (11) Regulator Drugs (0)Regulon Drugs (11)BEVACIZUMAB, CONBERCEPT, PEGAPTANIB SODIUM, PEGAPTANIB OCTASODIUM, MUPARFOSTAT, VANUCIZUMAB, RANIBIZUMAB, FARICIMAB, ABICIPAR PEGOL, AFLIBERCEPT, BROLUCIZUMAB |
| CMF-24561 | SEMA3C | down-regulates | SMAD1 | activates | R-1490 | 21 | 6 | Drugs (18) Regulator Drugs (0)Regulon Drugs (18)BEVACIZUMAB, CONBERCEPT, AMG-780, MEDI-3617, PEGAPTANIB SODIUM, ENIBARCIMAB, TREBANANIB, PEGAPTANIB OCTASODIUM, MUPARFOSTAT, VANUCIZUMAB, PROBUCOL, RANIBIZUMAB, FARICIMAB, CVX-060, ABICIPAR PEGOL, NESVACUMAB, AFLIBERCEPT, BROLUCIZUMAB |
| CMF-24562 | SEMA3C | down-regulates | SMAD1 | activates | R-1484 | 21 | 6 | Drugs (41) Regulator Drugs (0)Regulon Drugs (41)POZIOTINIB, MM-111, TRASTUZUMAB DERUXTECAN, VARLITINIB, CUDC-101, LAPATINIB DITOSYLATE, TUCATINIB, HEMAY-022, MP-412, TRASTUZUMAB EMTANSINE, ZENOCUTUZUMAB, CANERTINIB DIHYDROCHLORIDE, NERATINIB MALEATE, MUBRITINIB, LAPATINIB, SAPITINIB, NERATINIB, BMS-690514, AC-480, DACOMITINIB, KBP5209, TARLOXOTINIB, VANDETANIB, ALLITINIB, ERTUMAXOMAB, TRASTUZUMAB DUOCARMAZINE, MARGETUXIMAB, TRASTUZUMAB, T-DM1, CANERTINIB, BDTX189, JNJ-26483327, TESEVATINIB, AFATINIB DIMALEATE, CP-724714, AFATINIB, AEE-788, PYROTINIB, TAK-285, PERTUZUMAB, GANCOTAMAB |
| CMF-24564 | SEMA3C | down-regulates | SMAD1 | activates | R-1495 | 21 | 6 | Drugs (7) |
| CMF-24565 | SEMA3C | down-regulates | SMAD1 | activates | R-1487 | 21 | 6 | Drugs (24) Regulator Drugs (0)Regulon Drugs (24)TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE |
| CMF-24567 | SEMA3C | down-regulates | CPEB1 | activates | R-3792 | 3 | 1 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |