| CMF-17920 | PRPF40B | up-regulates | SATB1 | represses | R-1679 | 24 | 9 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-17921 | PRPF40B | up-regulates | SATB1 | represses | R-1684 | 24 | 9 | Drugs (9) |
| CMF-17924 | PRPF40B | up-regulates | SATB1 | represses | R-1681 | 24 | 9 | Drugs (23) Regulator Drugs (0)Regulon Drugs (23)TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE |
| CMF-17926 | PRPF40B | down-regulates | ELF5 | activates | R-3348 | 16 | 2 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)EMRICASAN |
| CMF-17927 | PRPF40B | down-regulates | PPARG | activates | R-2322 | 15 | 4 | Drugs (8) |
| CMF-17928 | PRPF40B | down-regulates | PPARG | activates | R-2329 | 15 | 4 | Drugs (6) |
| CMF-17929 | PRPF40B | down-regulates | PPARG | activates | R-2323 | 15 | 4 | Drugs (5) |
| CMF-17933 | PRPF40B | down-regulates | ATF3 | activates | R-466 | 5 | 2 | Drugs (4) |
| CMF-17935 | PRPF40B | down-regulates | MAFB | activates | R-1912 | 25 | 10 | Drugs (4) |
| CMF-17936 | PRPF40B | down-regulates | MAFB | activates | R-1905 | 25 | 10 | Drugs (6) |
| CMF-17938 | PRPF40B | down-regulates | MAFB | activates | R-1902 | 25 | 10 | Drugs (29) Regulator Drugs (0)Regulon Drugs (29)FOSTAMATINIB DISODIUM, FIBOFLAPON SODIUM, HYDROXYCHLOROQUINE, R-343, AME-133V, R-348, CERDULATINIB, VESATOLIMOD, AZD-8848, EFALIZUMAB, HMPL-523, HYDROXYCHLOROQUINE SULFATE, PETESICATIB, ENTOSPLETINIB, CPG-52852, R-333, IMIQUIMOD, IC14, GUSACITINIB, LIFITEGRAST, VB-201, GSK-2245035, MIVAVOTINIB CITRATE, VELIFLAPON, TELRATOLIMOD, FOSTAMATINIB, LANRAPLENIB, MIVAVOTINIB, FIBOFLAPON |
| CMF-17940 | PRPF40B | down-regulates | MAFB | activates | R-1911 | 25 | 10 | Drugs (23) Regulator Drugs (0)Regulon Drugs (23)TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE |
| CMF-17941 | PRPF40B | down-regulates | MAFB | activates | R-1903 | 25 | 10 | Drugs (8) |
| CMF-17942 | PRPF40B | down-regulates | MAFB | activates | R-1907 | 25 | 10 | Drugs (15) Regulator Drugs (0)Regulon Drugs (15)SCH-708980, CANAKINUMAB, RILONACEPT, MEDI-5117, GEVOKIZUMAB, CLAZAKIZUMAB, OLOKIZUMAB, SILTUXIMAB, MRA 003 US, LUTIKIZUMAB, PF-04236921, GLEMBATUMUMAB VEDOTIN, GLEMBATUMUMAB, SIRUKUMAB, ZILTIVEKIMAB |
| CMF-17945 | PRPF40B | down-regulates | HMGA1 | activates | R-1073 | 16 | 7 | Drugs (4) |
| CMF-17946 | PRPF40B | down-regulates | HMGA1 | activates | R-1071 | 16 | 7 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-17948 | PRPF40B | down-regulates | HMGA1 | activates | R-1081 | 16 | 7 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-17950 | PRPF40B | down-regulates | HMGA1 | activates | R-1067 | 16 | 7 | Drugs (7) |
| CMF-17956 | PRPF40B | down-regulates | SPI1 | activates | R-378 | 25 | 15 | Drugs (7) |
| CMF-17957 | PRPF40B | down-regulates | SPI1 | activates | R-376 | 25 | 15 | Drugs (88) Regulator Drugs (0)Regulon Drugs (88)IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, SCH-708980, CIMICOXIB, ACETAMINOPHEN, OXYPHENBUTAZONE, CELECOXIB, CANAKINUMAB, MELOXICAM, BROMFENAC SODIUM, RILONACEPT, ACECLOFENAC, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, APRICOXIB, MEDI-5117, GEVOKIZUMAB, NAPROXEN SODIUM, DEXKETOPROFEN, PARECOXIB, ASPIRIN, ESFLURBIPROFEN, CLAZAKIZUMAB, ALOXIPRIN, ETORICOXIB, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, LUMIRACOXIB, NAPROXEN, DICLOFENAC EPOLAMINE, OLOKIZUMAB, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, NABUMETONE, ROFECOXIB, MESALAMINE, SILTUXIMAB, MRA 003 US, ACEMETACIN, PARECOXIB SODIUM, IBUPROFEN SODIUM, LUTIKIZUMAB, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, ETODOLAC, SUPROFEN, PF-04236921, SULFASALAZINE, MECLOFENAMATE SODIUM, GW-406381, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, GLEMBATUMUMAB VEDOTIN, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, GLEMBATUMUMAB, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, SIRUKUMAB, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN, IGURATIMOD, VALDECOXIB, POLMACOXIB, ZILTIVEKIMAB |
| CMF-17962 | PRPF40B | down-regulates | SPI1 | activates | R-379 | 25 | 15 | Drugs (24) Regulator Drugs (0)Regulon Drugs (24)TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE |
| CMF-17964 | PRPF40B | down-regulates | SPI1 | activates | R-370 | 25 | 15 | Drugs (199) Regulator Drugs (0)Regulon Drugs (199)PF-04691502, LY-2787106, FOSTAMATINIB DISODIUM, PICOTAMIDE, SARGRAMOSTIM, UMBRALISIB, PAZOPANIB, MIDOSTAURIN, FIBOFLAPON SODIUM, ATN-161, BGT-226, SONOLISIB, RUPATADINE, CSL-324, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, INTERFERON GAMMA-1B, R-343, VOXTALISIB, BMS-986142, HM-71224, SUNITINIB, CINTREDEKIN BESUDOTOX, NEMIRALISIB, RP-6530, BIIB-023, APITOLISIB, AME-133V, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, MSC-2364447, PAXALISIB, AS-1409, PICTILISIB, CCR5MAB004, R-348, PEXIDARTINIB HYDROCHLORIDE, PF-06651600, AMY-101, LIPEGFILGRASTIM, ABIVERTINIB, VRC-01LS, PAZOPANIB HYDROCHLORIDE, ABIVERTINIB MALEATE, VICRIVIROC, MEDI-2338, VATALANIB, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, AVE-9633, VOBARILIZUMAB, CERDULATINIB, VESATOLIMOD, DUVELISIB, CAROTUXIMAB, L19TNFA, EDICOTINIB, APLAVIROC, MARAVIROC, AZD-8848, SUNITINIB MALATE, EFALIZUMAB, DACTOLISIB, BOSUTINIB, BAFETINIB, FILGRASTIM, ZANDELISIB, HMPL-523, PLX-7486, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, LERONLIMAB, RILZABRUTINIB, BALUGRASTIM, SPEBRUTINIB, SOTRASTAURIN, PILARALISIB, ILORASERTIB, DAPANSUTRILE, ENMD-2076, RO-5458640, CCX354, PREXIGEBERSEN, AMG-820, TASELISIB, JNJ-26483327, L19SIP 131I, AMG-319, UCN-01, IBRUTINIB, TADEKINIG ALFA, HYDROXYCHLOROQUINE SULFATE, HGS-1025, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, PLX-5622, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, NEIHULIZUMAB, GEMTUZUMAB, ENTOLIMOD, CENICRIVIROC, IDELALISIB, APLAVIROC HYDROCHLORIDE, AZD4818, ZANUBRUTINIB, XL-228, FIMEPINOSTAT, ENTOSPLETINIB, SATRALIZUMAB, EVOBRUTINIB, CPG-52852, R-333, IMIQUIMOD, IC14, OTLERTUZUMAB, GUSACITINIB, BI-836826, TOLIMIDONE, MAVRILIMUMAB, TREGALIZUMAB, ERITORAN TETRASODIUM, BMS-813160, GEMTUZUMAB OZOGAMICIN, PF-04634817, TG100-801, INCB-9471, SPEBRUTINIB BESYLATE, PEGCETACOPLAN, VICRIVIROC MALEATE, LENOGRASTIM, POSELTINIB, PEXIDARTINIB, LIFITEGRAST, VB-201, QUIZARTINIB, ACALISIB, PF-232798, ZANOLIMUMAB, GSK-2245035, MIVAVOTINIB CITRATE, VELIFLAPON, BMS-817399, PIRTOBRUTINIB, TELRATOLIMOD, AZD5672, IBALIZUMAB, OCRIPLASMIN, CAL-263, UB-421, ACALABRUTINIB, ERITORAN, MILATUZUMAB, VOLOCIXIMAB, LINIFANIB, FOSTAMATINIB, ELSUBRUTINIB, IMC-CS4, BRANEBRUTINIB, LENIOLISIB, OZAGREL, PA-799, ARRY-382, EMACTUZUMAB, LINTUZUMAB, TIRABRUTINIB, DELCASERTIB, FENEBRUTINIB, LEVILIMAB, GSK-1059615, LANRAPLENIB, MIVAVOTINIB, PEGFILGRASTIM, BUPARLISIB, VESENCUMAB, NARATUXIMAB EMTANSINE, GSK-690693, SF-1126, ORELABRUTINIB, GSK-1070806, FIBOFLAPON, CABIRALIZUMAB, AL-78898A, ENMD-981693, PANULISIB, AXATILIMAB |
| CMF-17965 | PRPF40B | down-regulates | SPI1 | activates | R-377 | 25 | 15 | Drugs (8) |
| CMF-17966 | PRPF40B | down-regulates | SPI1 | activates | R-371 | 25 | 15 | Drugs (31) Regulator Drugs (0)Regulon Drugs (31)RILAPLADIB, CALCIFEDIOL, BECOCALCIDIOL, TACROLIMUS, INTERFERON GAMMA-1B, TEMSIROLIMUS, PARICALCITOL, INECALCITOL, BATOCLIMAB, ERGOCALCIFEROL, CHOLECALCIFEROL, NIPOCALIMAB, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, EVEROLIMUS, DARAPLADIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SIROLIMUS, EFGARTIGIMOD ALFA, SEOCALCITOL, ROZANOLIXIZUMAB, VERNAKALANT, PEFCALCITOL, VERNAKALANT HYDROCHLORIDE, LUNACALCIPOL, PIMECROLIMUS, DP001, ALFACALCIDOL |
| CMF-17967 | PRPF40B | down-regulates | SPI1 | activates | R-385 | 25 | 15 | Drugs (8) |
| CMF-17968 | PRPF40B | up-regulates | SOX10 | represses | R-3063 | 8 | 3 | Drugs (33) Regulator Drugs (0)Regulon Drugs (33)SAVOLITINIB, TELISOTUZUMAB VEDOTIN, AMUVATINIB, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, TEPOTINIB HYDROCHLORIDE, FORETINIB, ONARTUZUMAB, SAR-125844, AMG-208, MK-8033, AMG-337, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, MK-2461, MERESTINIB, BMS-777607, CAPMATINIB, JNJ-38877605, GLESATINIB, BMS-817378, CABOZANTINIB S-MALATE, CRIZOTINIB, EMD-1204831, TIVANTINIB, TELISOTUZUMAB, TEPOTINIB, EMIBETUZUMAB, BPI-9016, PF-04217903, GOLVATINIB |
| CMF-17969 | PRPF40B | up-regulates | SOX10 | represses | R-3066 | 8 | 3 | Drugs (4) |
| CMF-17970 | PRPF40B | up-regulates | SOX10 | represses | R-3070 | 8 | 3 | Drugs (2) |
| CMF-17972 | PRPF40B | up-regulates | THRA | represses | R-97 | 11 | 3 | Drugs (59) Regulator Drugs (0)Regulon Drugs (59)PF-04691502, BGT-226, SONOLISIB, VOXTALISIB, BMS-986142, HM-71224, PICLIDENOSON, APITOLISIB, DS-7423, L19IL2, MSC-2364447, PAXALISIB, AS-1409, PICTILISIB, PF-06651600, ABIVERTINIB, ABIVERTINIB MALEATE, CAFFEINE, CITRATED, VS-5584, SAMOTOLISIB, L19TNFA, DACTOLISIB, GNF-Pf-5468, WX-037, RILZABRUTINIB, SPEBRUTINIB, PILARALISIB, TASELISIB, L19SIP 131I, IBRUTINIB, GEDATOLISIB, OMIPALISIB, ZANUBRUTINIB, EVOBRUTINIB, OTLERTUZUMAB, BI-836826, CAFFEINE, SPEBRUTINIB BESYLATE, POSELTINIB, ADENOSINE, PIRTOBRUTINIB, OCRIPLASMIN, ACALABRUTINIB, OXTRIPHYLLINE, ELSUBRUTINIB, BRANEBRUTINIB, NAMODENOSON, PA-799, TIRABRUTINIB, FENEBRUTINIB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, THEOPHYLLINE, SF-1126, ORELABRUTINIB, AMINOPHYLLINE, PANULISIB, NELFINAVIR |
| CMF-17974 | PRPF40B | down-regulates | ATF5 | activates | R-362 | 14 | 10 | Drugs (6) |
| CMF-17975 | PRPF40B | down-regulates | ATF5 | activates | R-359 | 14 | 10 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)EMRICASAN |
| CMF-17976 | PRPF40B | down-regulates | ATF5 | activates | R-358 | 14 | 10 | Drugs (3) |
| CMF-17977 | PRPF40B | down-regulates | ATF5 | activates | R-365 | 14 | 10 | Drugs (6) |
| CMF-17978 | PRPF40B | down-regulates | ATF5 | activates | R-356 | 14 | 10 | Drugs (108) Regulator Drugs (0)Regulon Drugs (108)PF-04691502, UMBRALISIB, FIBOFLAPON SODIUM, BGT-226, SONOLISIB, CSL-324, HYDROXYCHLOROQUINE, PARSACLISIB, INTERFERON GAMMA-1B, VOXTALISIB, BMS-986142, HM-71224, NEMIRALISIB, RP-6530, APITOLISIB, AME-133V, DS-7423, GSK-2269557, L19IL2, INCB-40093, MSC-2364447, PAXALISIB, AS-1409, PICTILISIB, PF-06651600, AMY-101, LIPEGFILGRASTIM, ABIVERTINIB, VRC-01LS, ABIVERTINIB MALEATE, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, EFALIZUMAB, DACTOLISIB, FILGRASTIM, ZANDELISIB, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, RILZABRUTINIB, BALUGRASTIM, SPEBRUTINIB, PILARALISIB, TASELISIB, L19SIP 131I, AMG-319, IBRUTINIB, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, ZANUBRUTINIB, FIMEPINOSTAT, SATRALIZUMAB, EVOBRUTINIB, CPG-52852, IMIQUIMOD, IC14, TREGALIZUMAB, ERITORAN TETRASODIUM, SPEBRUTINIB BESYLATE, PEGCETACOPLAN, LENOGRASTIM, POSELTINIB, LIFITEGRAST, VB-201, ACALISIB, ZANOLIMUMAB, GSK-2245035, VELIFLAPON, PIRTOBRUTINIB, TELRATOLIMOD, IBALIZUMAB, OCRIPLASMIN, CAL-263, UB-421, ACALABRUTINIB, ERITORAN, ELSUBRUTINIB, BRANEBRUTINIB, LENIOLISIB, PA-799, TIRABRUTINIB, FENEBRUTINIB, LEVILIMAB, GSK-1059615, PEGFILGRASTIM, BUPARLISIB, VESENCUMAB, SF-1126, ORELABRUTINIB, FIBOFLAPON, AL-78898A, PANULISIB |
| CMF-17985 | PRPF40B | down-regulates | BCL6 | activates | R-629 | 23 | 11 | Drugs (24) Regulator Drugs (0)Regulon Drugs (24)TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE |
| CMF-17986 | PRPF40B | down-regulates | BCL6 | activates | R-626 | 23 | 11 | Drugs (8) |
| CMF-17991 | PRPF40B | down-regulates | BCL6 | activates | R-622 | 23 | 11 | Drugs (71) Regulator Drugs (0)Regulon Drugs (71)ESTROGENS, ESTERIFIED, SAVOLITINIB, TELISOTUZUMAB VEDOTIN, ATN-161, RALOXIFENE, PRINABEREL, LASOFOXIFENE, AMUVATINIB, BAZEDOXIFENE ACETATE, CHLOROTRIANISENE, ESTRIOL, BIRINAPANT, ACOLBIFENE, CABOZANTINIB, ALTIRATINIB, SGX-523, TEREVALEFIM, SYNTHETIC CONJUGATED ESTROGENS, B, OSPEMIFENE, TEPOTINIB HYDROCHLORIDE, TOREMIFENE CITRATE, FORETINIB, RALOXIFENE HYDROCHLORIDE, ONARTUZUMAB, SAR-125844, ERTEBEREL, AMG-208, FULVESTRANT, CILENGITIDE, TIROFIBAN HYDROCHLORIDE, ESTROGENS, CONJUGATED SYNTHETIC A, ESTROGENS, CONJUGATED, MK-8033, FISPEMIFENE, AMG-337, ABCIXIMAB, CAPMATINIB HYDROCHLORIDE, AMIVANTAMAB, AFIMOXIFENE, MK-2461, MERESTINIB, DIETHYLSTILBESTROL DIPHOSPHATE, BMS-777607, BAZEDOXIFENE, CAPMATINIB, ETARACIZUMAB, JNJ-38877605, GLESATINIB, INTETUMUMAB, BMS-817378, CABOZANTINIB S-MALATE, MF101, AUS-131, CRIZOTINIB, TOREMIFENE, EMD-1204831, TIVANTINIB, ESTRAMUSTINE PHOSPHATE, NEDOSIRAN SODIUM, TELISOTUZUMAB, ESTETROL, TEPOTINIB, EMIBETUZUMAB, BPI-9016, ESTRAMUSTINE PHOSPHATE SODIUM, PF-04217903, ARZOXIFENE, EPTIFIBATIDE, ABITUZUMAB, GOLVATINIB, TIROFIBAN |
| CMF-17992 | PRPF40B | down-regulates | BCL6 | activates | R-632 | 23 | 11 | Drugs (8) |
| CMF-17996 | PRPF40B | down-regulates | IRF5 | activates | R-1085 | 11 | 4 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-18003 | PRPF40B | up-regulates | SOX5 | represses | R-257 | 18 | 6 | Drugs (149) Regulator Drugs (0)Regulon Drugs (149)PF-04691502, FOSTAMATINIB DISODIUM, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, FIBOFLAPON SODIUM, BGT-226, SONOLISIB, RUPATADINE, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, INTERFERON GAMMA-1B, ONERCEPT, R-343, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, ABATACEPT, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, CCR5MAB004, R-348, AMY-101, PEGSUNERCEPT, GOLIMUMAB, VICRIVIROC, CAFFEINE, CITRATED, MEDI-2338, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, AVE-9633, VOBARILIZUMAB, CERDULATINIB, VESATOLIMOD, DUVELISIB, L19TNFA, APLAVIROC, MARAVIROC, AZD-8848, DACTOLISIB, BOSUTINIB, BAFETINIB, ZANDELISIB, HMPL-523, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, LERONLIMAB, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, TASELISIB, JNJ-26483327, L19SIP 131I, AMG-319, UCN-01, TADEKINIG ALFA, HYDROXYCHLOROQUINE SULFATE, HGS-1025, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, NEIHULIZUMAB, GEMTUZUMAB, CENICRIVIROC, IDELALISIB, APLAVIROC HYDROCHLORIDE, BELATACEPT, XL-228, FIMEPINOSTAT, ENTOSPLETINIB, SATRALIZUMAB, CPG-52852, SELGANTOLIMOD, R-333, IMIQUIMOD, GUSACITINIB, REMTOLUMAB, TOLIMIDONE, CAFFEINE, MOTOLIMOD, TOMIVOSERTIB, BMS-813160, GEMTUZUMAB OZOGAMICIN, PF-04634817, TG100-801, INCB-9471, PEGCETACOPLAN, VICRIVIROC MALEATE, ADENOSINE, DUPILUMAB, ACALISIB, PF-232798, GSK-2245035, MIVAVOTINIB CITRATE, VELIFLAPON, TELRATOLIMOD, AZD5672, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, MILATUZUMAB, FOSTAMATINIB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, LINTUZUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, LANRAPLENIB, MIVAVOTINIB, BUPARLISIB, VESENCUMAB, GSK-690693, THEOPHYLLINE, SF-1126, AMINOPHYLLINE, GSK-1070806, FIBOFLAPON, AL-78898A, ENMD-981693, PANULISIB |
| CMF-18004 | PRPF40B | up-regulates | SOX5 | represses | R-259 | 18 | 6 | Drugs (17) Regulator Drugs (0)Regulon Drugs (17)CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, BRENSOCATIB, ELDECALCITOL, CALCIPOTRIENE, EMRICASAN, SEOCALCITOL, PEFCALCITOL, LUNACALCIPOL, DP001, ALFACALCIDOL |
| CMF-18005 | PRPF40B | up-regulates | SOX5 | represses | R-258 | 18 | 6 | Drugs (9) |
| CMF-18007 | PRPF40B | up-regulates | NR3C2 | activates | R-2018 | 2 | 1 | Drugs (3) |
| CMF-18010 | PRPF40B | down-regulates | ARID5A | activates | R-160 | 15 | 8 | Drugs (2) |
| CMF-18012 | PRPF40B | down-regulates | ARID5A | activates | R-162 | 15 | 8 | Drugs (6) |
| CMF-18014 | PRPF40B | down-regulates | ARID5A | activates | R-165 | 15 | 8 | Drugs (5) |
| CMF-18015 | PRPF40B | down-regulates | ARID5A | activates | R-158 | 15 | 8 | Drugs (110) Regulator Drugs (0)Regulon Drugs (110)PF-04691502, PICOTAMIDE, UMBRALISIB, FIBOFLAPON SODIUM, ATN-161, BGT-226, SONOLISIB, RUPATADINE, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, INTERFERON GAMMA-1B, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, CCR5MAB004, VICRIVIROC, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, AVE-9633, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, APLAVIROC, MARAVIROC, AZD-8848, DACTOLISIB, ZANDELISIB, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, LERONLIMAB, PILARALISIB, ILORASERTIB, PREXIGEBERSEN, TASELISIB, L19SIP 131I, AMG-319, HYDROXYCHLOROQUINE SULFATE, HGS-1025, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, GEMTUZUMAB, CENICRIVIROC, IDELALISIB, APLAVIROC HYDROCHLORIDE, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, CAFFEINE, BMS-813160, GEMTUZUMAB OZOGAMICIN, PF-04634817, TG100-801, INCB-9471, VICRIVIROC MALEATE, ADENOSINE, VB-201, DUPILUMAB, ACALISIB, PF-232798, GSK-2245035, VELIFLAPON, TELRATOLIMOD, AZD5672, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, MILATUZUMAB, VOLOCIXIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, LINTUZUMAB, LEVILIMAB, GSK-1059615, BUPARLISIB, THEOPHYLLINE, SF-1126, AMINOPHYLLINE, FIBOFLAPON, ENMD-981693, PANULISIB, NELFINAVIR |
| CMF-18017 | PRPF40B | down-regulates | ARID5A | activates | R-167 | 15 | 8 | Drugs (2) |
| CMF-18018 | PRPF40B | down-regulates | SPIB | activates | R-3629 | 4 | 1 | Drugs (3) |
| CMF-18020 | PRPF40B | down-regulates | PRDM1 | activates | R-153 | 21 | 12 | Drugs (17) Regulator Drugs (0)Regulon Drugs (17)CALCIFEDIOL, BECOCALCIDIOL, PARICALCITOL, INECALCITOL, ERGOCALCIFEROL, CHOLECALCIFEROL, DOXERCALCIFEROL, CALCITRIOL, ELDECALCITOL, CALCIPOTRIENE, SEOCALCITOL, MIFAMURTIDE, PEFCALCITOL, LUNACALCIPOL, TOSEDOSTAT, DP001, ALFACALCIDOL |
| CMF-18021 | PRPF40B | down-regulates | PRDM1 | activates | R-142 | 21 | 12 | Drugs (24) Regulator Drugs (0)Regulon Drugs (24)TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE |
| CMF-18022 | PRPF40B | down-regulates | PRDM1 | activates | R-137 | 21 | 12 | Drugs (144) Regulator Drugs (0)Regulon Drugs (144)PF-04691502, FOSTAMATINIB DISODIUM, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, CSL-324, PARSACLISIB, INTERFERON GAMMA-1B, R-343, VOXTALISIB, BMS-986142, HM-71224, NEMIRALISIB, RP-6530, BIIB-023, APITOLISIB, AME-133V, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, MSC-2364447, PAXALISIB, AS-1409, PICTILISIB, R-348, PF-06651600, LIPEGFILGRASTIM, ABIVERTINIB, VRC-01LS, ABIVERTINIB MALEATE, MEDI-2338, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, CERDULATINIB, DUVELISIB, CAROTUXIMAB, L19TNFA, EFALIZUMAB, DACTOLISIB, BOSUTINIB, BAFETINIB, FILGRASTIM, ZANDELISIB, HMPL-523, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, RILZABRUTINIB, BALUGRASTIM, SPEBRUTINIB, SOTRASTAURIN, PILARALISIB, ILORASERTIB, DAPANSUTRILE, RO-5458640, MUPARFOSTAT, CCX354, TASELISIB, JNJ-26483327, L19SIP 131I, AMG-319, UCN-01, IBRUTINIB, TADEKINIG ALFA, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, NEIHULIZUMAB, ENTOLIMOD, IDELALISIB, AZD4818, ZANUBRUTINIB, XL-228, FIMEPINOSTAT, ENTOSPLETINIB, SATRALIZUMAB, EVOBRUTINIB, SELGANTOLIMOD, R-333, IC14, OTLERTUZUMAB, GUSACITINIB, BI-836826, TOLIMIDONE, MOTOLIMOD, TREGALIZUMAB, ERITORAN TETRASODIUM, TG100-801, SPEBRUTINIB BESYLATE, LENOGRASTIM, POSELTINIB, LIFITEGRAST, VB-201, ACALISIB, ZANOLIMUMAB, MIVAVOTINIB CITRATE, BMS-817399, PIRTOBRUTINIB, TELRATOLIMOD, IBALIZUMAB, OCRIPLASMIN, CAL-263, UB-421, ACALABRUTINIB, ERITORAN, MILATUZUMAB, VOLOCIXIMAB, FOSTAMATINIB, TOMARALIMAB, ELSUBRUTINIB, BRANEBRUTINIB, LENIOLISIB, PA-799, TIRABRUTINIB, DELCASERTIB, FENEBRUTINIB, LEVILIMAB, GSK-1059615, LANRAPLENIB, MIVAVOTINIB, PEGFILGRASTIM, BUPARLISIB, VESENCUMAB, NARATUXIMAB EMTANSINE, GSK-690693, AMG-557, SF-1126, ORELABRUTINIB, GSK-1070806, ENMD-981693, PANULISIB |
| CMF-18023 | PRPF40B | down-regulates | PRDM1 | activates | R-138 | 21 | 12 | Drugs (4) |
| CMF-18025 | PRPF40B | down-regulates | PRDM1 | activates | R-146 | 21 | 12 | Drugs (3) |
| CMF-18026 | PRPF40B | down-regulates | PRDM1 | activates | R-152 | 21 | 12 | Drugs (1) |
| CMF-18027 | PRPF40B | down-regulates | PRDM1 | activates | R-145 | 21 | 12 | Drugs (5) |
| CMF-18030 | PRPF40B | down-regulates | PRDM1 | activates | R-150 | 21 | 12 | Drugs (1) |
| CMF-18033 | PRPF40B | up-regulates | NF1 | represses | R-2310 | 11 | 3 | Drugs (2) |
| CMF-18034 | PRPF40B | up-regulates | NF1 | represses | R-2309 | 11 | 3 | Drugs (1) |
| CMF-18035 | PRPF40B | up-regulates | NF1 | represses | R-2305 | 11 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-18037 | PRPF40B | up-regulates | SCRT1 | represses | R-108 | 4 | 2 | Drugs (12) Regulator Drugs (0)Regulon Drugs (12)DASATINIB, VOBARILIZUMAB, CAROTUXIMAB, TOCILIZUMAB, ILORASERTIB, SARILUMAB, XL-228, SATRALIZUMAB, TOMIVOSERTIB, TG100-801, LEVILIMAB, ENMD-981693 |
| CMF-18040 | PRPF40B | up-regulates | LHX6 | represses | R-2249 | 4 | 2 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)APATORSEN |
| CMF-18042 | PRPF40B | down-regulates | CEBPB | activates | R-1305 | 23 | 8 | Drugs (5) |
| CMF-18044 | PRPF40B | down-regulates | CEBPB | activates | R-1308 | 23 | 8 | Drugs (3) |
| CMF-18045 | PRPF40B | down-regulates | CEBPB | activates | R-1304 | 23 | 8 | Drugs (6) |
| CMF-18046 | PRPF40B | down-regulates | CEBPB | activates | R-1314 | 23 | 8 | Drugs (1) |
| CMF-18047 | PRPF40B | down-regulates | CEBPB | activates | R-1306 | 23 | 8 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)ANG1005 |
| CMF-18053 | PRPF40B | down-regulates | RUNX3 | activates | R-194 | 11 | 6 | Drugs (8) |
| CMF-18054 | PRPF40B | down-regulates | RUNX3 | activates | R-192 | 11 | 6 | Drugs (56) Regulator Drugs (0)Regulon Drugs (56)LY-2787106, SARGRAMOSTIM, ATN-161, AME-133V, DASATINIB, ABATACEPT, L19IL2, AS-1409, CCR5MAB004, VRC-01LS, VICRIVIROC, VOBARILIZUMAB, CAROTUXIMAB, L19TNFA, APLAVIROC, MARAVIROC, EFALIZUMAB, BOSUTINIB, BAFETINIB, TOCILIZUMAB, LERONLIMAB, ILORASERTIB, JNJ-26483327, L19SIP 131I, HGS-1025, PF-04605412, SARILUMAB, CENICRIVIROC, APLAVIROC HYDROCHLORIDE, BELATACEPT, XL-228, SATRALIZUMAB, SELGANTOLIMOD, TOLIMIDONE, MAVRILIMUMAB, MOTOLIMOD, TREGALIZUMAB, ERITORAN TETRASODIUM, TOMIVOSERTIB, BMS-813160, PF-04634817, TG100-801, INCB-9471, VICRIVIROC MALEATE, LIFITEGRAST, PF-232798, ZANOLIMUMAB, TELRATOLIMOD, AZD5672, IBALIZUMAB, OCRIPLASMIN, UB-421, ERITORAN, VOLOCIXIMAB, LEVILIMAB, ENMD-981693 |
| CMF-18055 | PRPF40B | up-regulates | POU3F2 | represses | R-2161 | 17 | 5 | Drugs (2) |
| CMF-18059 | PRPF40B | down-regulates | BACH1 | activates | R-2747 | 11 | 4 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-18060 | PRPF40B | down-regulates | BACH1 | activates | R-2752 | 11 | 4 | Drugs (21) Regulator Drugs (0)Regulon Drugs (21)TRELAGLIPTIN SUCCINATE, VILDAGLIPTIN, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE |
| CMF-18061 | PRPF40B | down-regulates | BACH1 | activates | R-2749 | 11 | 4 | Drugs (5) |
| CMF-18062 | PRPF40B | down-regulates | BACH1 | activates | R-2746 | 11 | 4 | Drugs (3) |
| CMF-18064 | PRPF40B | down-regulates | NFIL3 | activates | R-3677 | 7 | 3 | Drugs (12) Regulator Drugs (0)Regulon Drugs (12)RIMEGEPANT SULFATE, THYROTROPIN, TELCAGEPANT, THYROTROPIN ALFA, ATOGEPANT, UBROGEPANT, ERENUMAB, RIMEGEPANT, BI-44370, MK3207, DAVALINTIDE, OLCEGEPANT |
| CMF-18072 | PRPF40B | down-regulates | FLI1 | activates | R-3267 | 11 | 5 | Drugs (6) |
| CMF-18075 | PRPF40B | down-regulates | FLI1 | activates | R-3264 | 11 | 5 | Drugs (3) |
| CMF-38958 | PRPF40B | up-regulates | hsa-mir-125b | represses | R-2053 | 10 | 10 | Drugs (9) |
| CMF-38959 | PRPF40B | up-regulates | hsa-mir-125b | represses | R-158 | 10 | 10 | Drugs (110) Regulator Drugs (0)Regulon Drugs (110)PF-04691502, PICOTAMIDE, UMBRALISIB, FIBOFLAPON SODIUM, ATN-161, BGT-226, SONOLISIB, RUPATADINE, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, INTERFERON GAMMA-1B, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, CCR5MAB004, VICRIVIROC, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, AVE-9633, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, APLAVIROC, MARAVIROC, AZD-8848, DACTOLISIB, ZANDELISIB, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, LERONLIMAB, PILARALISIB, ILORASERTIB, PREXIGEBERSEN, TASELISIB, L19SIP 131I, AMG-319, HYDROXYCHLOROQUINE SULFATE, HGS-1025, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, GEMTUZUMAB, CENICRIVIROC, IDELALISIB, APLAVIROC HYDROCHLORIDE, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, CAFFEINE, BMS-813160, GEMTUZUMAB OZOGAMICIN, PF-04634817, TG100-801, INCB-9471, VICRIVIROC MALEATE, ADENOSINE, VB-201, DUPILUMAB, ACALISIB, PF-232798, GSK-2245035, VELIFLAPON, TELRATOLIMOD, AZD5672, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, MILATUZUMAB, VOLOCIXIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, LINTUZUMAB, LEVILIMAB, GSK-1059615, BUPARLISIB, THEOPHYLLINE, SF-1126, AMINOPHYLLINE, FIBOFLAPON, ENMD-981693, PANULISIB, NELFINAVIR |
| CMF-38960 | PRPF40B | up-regulates | hsa-mir-125b | represses | R-246 | 10 | 10 | Drugs (63) Regulator Drugs (0)Regulon Drugs (63)PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, ATN-161, BGT-226, SONOLISIB, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, NEMIRALISIB, RP-6530, APITOLISIB, DS-7423, GSK-2269557, INCB-40093, PAXALISIB, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, DUVELISIB, DACTOLISIB, ZANDELISIB, ETANERCEPT, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, OZORALIZUMAB, PILARALISIB, CERTOLIZUMAB PEGOL, TASELISIB, AMG-319, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, FIMEPINOSTAT, REMTOLUMAB, DUPILUMAB, ACALISIB, CAL-263, ADALIMUMAB, VOLOCIXIMAB, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, GSK-1059615, BUPARLISIB, SF-1126, PANULISIB |
| CMF-38961 | PRPF40B | up-regulates | hsa-mir-125b | represses | R-257 | 10 | 10 | Drugs (149) Regulator Drugs (0)Regulon Drugs (149)PF-04691502, FOSTAMATINIB DISODIUM, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, FIBOFLAPON SODIUM, BGT-226, SONOLISIB, RUPATADINE, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, INTERFERON GAMMA-1B, ONERCEPT, R-343, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, ABATACEPT, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, CCR5MAB004, R-348, AMY-101, PEGSUNERCEPT, GOLIMUMAB, VICRIVIROC, CAFFEINE, CITRATED, MEDI-2338, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, AVE-9633, VOBARILIZUMAB, CERDULATINIB, VESATOLIMOD, DUVELISIB, L19TNFA, APLAVIROC, MARAVIROC, AZD-8848, DACTOLISIB, BOSUTINIB, BAFETINIB, ZANDELISIB, HMPL-523, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, LERONLIMAB, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, TASELISIB, JNJ-26483327, L19SIP 131I, AMG-319, UCN-01, TADEKINIG ALFA, HYDROXYCHLOROQUINE SULFATE, HGS-1025, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, NEIHULIZUMAB, GEMTUZUMAB, CENICRIVIROC, IDELALISIB, APLAVIROC HYDROCHLORIDE, BELATACEPT, XL-228, FIMEPINOSTAT, ENTOSPLETINIB, SATRALIZUMAB, CPG-52852, SELGANTOLIMOD, R-333, IMIQUIMOD, GUSACITINIB, REMTOLUMAB, TOLIMIDONE, CAFFEINE, MOTOLIMOD, TOMIVOSERTIB, BMS-813160, GEMTUZUMAB OZOGAMICIN, PF-04634817, TG100-801, INCB-9471, PEGCETACOPLAN, VICRIVIROC MALEATE, ADENOSINE, DUPILUMAB, ACALISIB, PF-232798, GSK-2245035, MIVAVOTINIB CITRATE, VELIFLAPON, TELRATOLIMOD, AZD5672, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, MILATUZUMAB, FOSTAMATINIB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, LINTUZUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, LANRAPLENIB, MIVAVOTINIB, BUPARLISIB, VESENCUMAB, GSK-690693, THEOPHYLLINE, SF-1126, AMINOPHYLLINE, GSK-1070806, FIBOFLAPON, AL-78898A, ENMD-981693, PANULISIB |
| CMF-38962 | PRPF40B | up-regulates | hsa-mir-125b | represses | R-290 | 10 | 10 | Drugs (110) Regulator Drugs (0)Regulon Drugs (110)PF-04691502, PICOTAMIDE, INFLIXIMAB, UMBRALISIB, MIDOSTAURIN, ATN-161, BGT-226, SONOLISIB, HYDROXYCHLOROQUINE, TERBOGREL, PARSACLISIB, ONERCEPT, VOXTALISIB, CINTREDEKIN BESUDOTOX, PICLIDENOSON, NEMIRALISIB, RP-6530, APITOLISIB, DASATINIB, DS-7423, GSK-2269557, L19IL2, INCB-40093, PAXALISIB, AS-1409, PICTILISIB, PEGSUNERCEPT, GOLIMUMAB, CAFFEINE, CITRATED, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, DACTOLISIB, ZANDELISIB, ETANERCEPT, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, AFELIMOMAB, SOTRASTAURIN, OZORALIZUMAB, PILARALISIB, ILORASERTIB, CERTOLIZUMAB PEGOL, CCX354, TASELISIB, L19SIP 131I, AMG-319, UCN-01, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, PETESICATIB, SELETALISIB, PF-04605412, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, AZD4818, XL-228, FIMEPINOSTAT, SATRALIZUMAB, CPG-52852, IMIQUIMOD, IC14, OTLERTUZUMAB, REMTOLUMAB, BI-836826, CAFFEINE, TG100-801, ADENOSINE, VB-201, ACALISIB, GSK-2245035, BMS-817399, TELRATOLIMOD, OCRIPLASMIN, CAL-263, OXTRIPHYLLINE, ADALIMUMAB, VOLOCIXIMAB, TOMARALIMAB, NAMODENOSON, LENIOLISIB, OZAGREL, PA-799, PLACULUMAB, DELCASERTIB, LEVILIMAB, GSK-1059615, BUPARLISIB, NARATUXIMAB EMTANSINE, GSK-690693, THEOPHYLLINE, AMG-557, SF-1126, AMINOPHYLLINE, ENMD-981693, PANULISIB, NELFINAVIR |
| CMF-38963 | PRPF40B | up-regulates | hsa-mir-125b | represses | R-356 | 10 | 10 | Drugs (108) Regulator Drugs (0)Regulon Drugs (108)PF-04691502, UMBRALISIB, FIBOFLAPON SODIUM, BGT-226, SONOLISIB, CSL-324, HYDROXYCHLOROQUINE, PARSACLISIB, INTERFERON GAMMA-1B, VOXTALISIB, BMS-986142, HM-71224, NEMIRALISIB, RP-6530, APITOLISIB, AME-133V, DS-7423, GSK-2269557, L19IL2, INCB-40093, MSC-2364447, PAXALISIB, AS-1409, PICTILISIB, PF-06651600, AMY-101, LIPEGFILGRASTIM, ABIVERTINIB, VRC-01LS, ABIVERTINIB MALEATE, TG100-115, VS-5584, COPANLISIB, SAMOTOLISIB, VOBARILIZUMAB, VESATOLIMOD, DUVELISIB, L19TNFA, AZD-8848, EFALIZUMAB, DACTOLISIB, FILGRASTIM, ZANDELISIB, TOCILIZUMAB, AZD-8186, GNF-Pf-5468, WX-037, RILZABRUTINIB, BALUGRASTIM, SPEBRUTINIB, PILARALISIB, TASELISIB, L19SIP 131I, AMG-319, IBRUTINIB, HYDROXYCHLOROQUINE SULFATE, COPANLISIB HYDROCHLORIDE, TENALISIB, SELETALISIB, GEDATOLISIB, OMIPALISIB, SARILUMAB, UMBRALISIB TOSYLATE, ENTOLIMOD, IDELALISIB, ZANUBRUTINIB, FIMEPINOSTAT, SATRALIZUMAB, EVOBRUTINIB, CPG-52852, IMIQUIMOD, IC14, TREGALIZUMAB, ERITORAN TETRASODIUM, SPEBRUTINIB BESYLATE, PEGCETACOPLAN, LENOGRASTIM, POSELTINIB, LIFITEGRAST, VB-201, ACALISIB, ZANOLIMUMAB, GSK-2245035, VELIFLAPON, PIRTOBRUTINIB, TELRATOLIMOD, IBALIZUMAB, OCRIPLASMIN, CAL-263, UB-421, ACALABRUTINIB, ERITORAN, ELSUBRUTINIB, BRANEBRUTINIB, LENIOLISIB, PA-799, TIRABRUTINIB, FENEBRUTINIB, LEVILIMAB, GSK-1059615, PEGFILGRASTIM, BUPARLISIB, VESENCUMAB, SF-1126, ORELABRUTINIB, FIBOFLAPON, AL-78898A, PANULISIB |
| CMF-38964 | PRPF40B | up-regulates | hsa-mir-125b | represses | R-378 | 10 | 10 | Drugs (7) |
| CMF-38965 | PRPF40B | up-regulates | hsa-mir-125b | represses | R-646 | 10 | 10 | Drugs (15) Regulator Drugs (0)Regulon Drugs (15)ALEPLASININ, SULTHIAME, CILENGITIDE, SENICAPOC, DKN-01, CG250 177LU, GIRENTUXIMAB, CG250 111IN, INTETUMUMAB, COLLAGENASE CLOSTRIDIUM HISTOLYTICUM, OCRIPLASMIN, TOSEDOSTAT, BHQ-880, VESENCUMAB, ABITUZUMAB |
| CMF-38966 | PRPF40B | up-regulates | hsa-mir-125b | represses | R-998 | 10 | 10 | Drugs (5) |
| CMF-38967 | PRPF40B | up-regulates | hsa-mir-125b | represses | R-3143 | 10 | 10 | Drugs (9) |