| CMF-06142 | MDGA2 | up-regulates | TEAD1 | activates | R-2399 | 15 | 1 | Drugs (11) Regulator Drugs (0)Regulon Drugs (11)AMG-780, MEDI-3617, ENIBARCIMAB, F16SIP 131I, TREBANANIB, F16IL2, VANUCIZUMAB, PROBUCOL, FARICIMAB, CVX-060, NESVACUMAB |
| CMF-06143 | MDGA2 | up-regulates | NR2E1 | activates | R-2391 | 9 | 3 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)ASK-8007 |
| CMF-06155 | MDGA2 | down-regulates | HOXA3 | represses | R-1465 | 22 | 6 | Drugs (4) |
| CMF-06157 | MDGA2 | down-regulates | HOXA3 | represses | R-1470 | 22 | 6 | Drugs (8) |
| CMF-06158 | MDGA2 | down-regulates | SOX1 | represses | R-1831 | 20 | 3 | Drugs (2) |
| CMF-06159 | MDGA2 | down-regulates | SOX1 | represses | R-1828 | 20 | 3 | Drugs (105) Regulator Drugs (0)Regulon Drugs (105)CISATRACURIUM, PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, GSK-1995057, RUPATADINE, DOXYLAMINE SUCCINATE, CISATRACURIUM BESYLATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, SUXAMETHONIUM, PRAMLINTIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, DICHLORPHENAMIDE, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, MIVACURIUM, EBASTINE, SULTHIAME, CINNARIZINE, VARESPLADIB METHYL, HYDROXYZINE, LORATADINE, LY2624803, ROCURONIUM BROMIDE, PHENIRAMINE MALEATE, ACETAZOLAMIDE, TRIPROLIDINE HYDROCHLORIDE, MIVACURIUM CHLORIDE, PRAMLINTIDE ACETATE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, TISOTUMAB VEDOTIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, VANTICTUMAB, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, ACETAZOLAMIDE SODIUM, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, ROCURONIUM, CETIRIZINE, METHDILAZINE, DAVALINTIDE |
| CMF-06161 | MDGA2 | down-regulates | POU4F1 | represses | R-2758 | 11 | 4 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-06162 | MDGA2 | down-regulates | POU4F1 | represses | R-2763 | 11 | 4 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)ASK-8007 |
| CMF-06163 | MDGA2 | down-regulates | POU4F1 | represses | R-2761 | 11 | 4 | Drugs (3) |
| CMF-06164 | MDGA2 | down-regulates | POU4F1 | activates | R-2764 | 11 | 4 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-06168 | MDGA2 | down-regulates | MAZ | activates | R-613 | 25 | 4 | Drugs (2) |
| CMF-06170 | MDGA2 | down-regulates | MAZ | activates | R-607 | 25 | 4 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-06173 | MDGA2 | down-regulates | SP4 | represses | R-2346 | 8 | 1 | Drugs (45) Regulator Drugs (0)Regulon Drugs (45)POZIOTINIB, MM-111, TRASTUZUMAB DERUXTECAN, VARLITINIB, CUDC-101, LAPATINIB DITOSYLATE, TUCATINIB, HEMAY-022, MP-412, TRASTUZUMAB EMTANSINE, ZENOCUTUZUMAB, CANERTINIB DIHYDROCHLORIDE, NERATINIB MALEATE, MUBRITINIB, LAPATINIB, SAPITINIB, NERATINIB, BMS-690514, AC-480, DACOMITINIB, KBP5209, TARLOXOTINIB, VANDETANIB, ALLITINIB, ERTUMAXOMAB, TRASTUZUMAB DUOCARMAZINE, MARGETUXIMAB, TRASTUZUMAB, T-DM1, CANERTINIB, BDTX189, JNJ-26483327, TESEVATINIB, JI-101, AFATINIB DIMALEATE, CP-724714, AFATINIB, TG100-801, OCRIPLASMIN, AEE-788, PYROTINIB, TAK-285, PERTUZUMAB, GSK-690693, GANCOTAMAB |
| CMF-06174 | MDGA2 | down-regulates | TFAP2C | represses | R-1340 | 15 | 2 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-06178 | MDGA2 | down-regulates | POU4F2 | represses | R-2790 | 13 | 2 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)ASK-8007 |
| CMF-06182 | MDGA2 | down-regulates | E2F1 | activates | R-530 | 18 | 5 | Drugs (1) |
| CMF-06187 | MDGA2 | down-regulates | PKNOX1 | activates | R-2338 | 4 | 1 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-06188 | MDGA2 | down-regulates | ELF3 | represses | R-3683 | 14 | 2 | Drugs (20) Regulator Drugs (0)Regulon Drugs (20)BEVACIZUMAB, CONBERCEPT, AMG-780, MEDI-3617, PEGAPTANIB SODIUM, ENIBARCIMAB, F16SIP 131I, TREBANANIB, PEGAPTANIB OCTASODIUM, MUPARFOSTAT, F16IL2, VANUCIZUMAB, PROBUCOL, RANIBIZUMAB, FARICIMAB, CVX-060, ABICIPAR PEGOL, NESVACUMAB, AFLIBERCEPT, BROLUCIZUMAB |
| CMF-35105 | MDGA2 | down-regulates | hsa-mir-95 | represses | R-61 | 73 | 8 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)PROBUCOL |
| CMF-35106 | MDGA2 | down-regulates | hsa-mir-95 | represses | R-2431 | 73 | 8 | Drugs (2) |
| CMF-35107 | MDGA2 | down-regulates | hsa-mir-95 | represses | R-651 | 73 | 8 | Drugs (2) |
| CMF-35108 | MDGA2 | down-regulates | hsa-mir-95 | represses | R-2797 | 73 | 8 | Drugs (1) |
| CMF-35109 | MDGA2 | down-regulates | hsa-mir-95 | represses | R-2830 | 73 | 8 | Drugs (2) |
| CMF-35110 | MDGA2 | down-regulates | hsa-mir-95 | represses | R-2864 | 73 | 8 | Drugs (2) |
| CMF-35111 | MDGA2 | down-regulates | hsa-mir-95 | represses | R-3033 | 73 | 8 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-35112 | MDGA2 | down-regulates | hsa-mir-95 | represses | R-3180 | 73 | 8 | Drugs (1) Regulator Drugs (0)Regulon Drugs (1)ANG1005 |
| CMF-35113 | MDGA2 | down-regulates | hsa-mir-375 | represses | R-2125 | 61 | 11 | Drugs (2) |
| CMF-35114 | MDGA2 | down-regulates | hsa-mir-375 | represses | R-2175 | 61 | 11 | Drugs (1) |
| CMF-35115 | MDGA2 | down-regulates | hsa-mir-375 | represses | R-575 | 61 | 11 | Drugs (6) |
| CMF-35116 | MDGA2 | down-regulates | hsa-mir-375 | represses | R-2652 | 61 | 11 | Drugs (1) |
| CMF-35117 | MDGA2 | down-regulates | hsa-mir-375 | represses | R-2797 | 61 | 11 | Drugs (1) |
| CMF-35118 | MDGA2 | down-regulates | hsa-mir-375 | represses | R-752 | 61 | 11 | Drugs (1) |
| CMF-35119 | MDGA2 | down-regulates | hsa-mir-375 | represses | R-993 | 61 | 11 | Drugs (4) |
| CMF-35120 | MDGA2 | down-regulates | hsa-mir-375 | represses | R-1568 | 61 | 11 | Drugs (3) |
| CMF-35121 | MDGA2 | down-regulates | hsa-mir-375 | represses | R-1772 | 61 | 11 | Drugs (89) Regulator Drugs (0)Regulon Drugs (89)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, RUPATADINE, DOXYLAMINE SUCCINATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, EBASTINE, CINNARIZINE, OLECLUMAB, HYDROXYZINE, LORATADINE, LY2624803, BELZUTIFAN, PHENIRAMINE MALEATE, TRIPROLIDINE HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, CETIRIZINE, METHDILAZINE |
| CMF-35122 | MDGA2 | down-regulates | hsa-mir-375 | represses | R-1938 | 61 | 11 | Drugs (89) Regulator Drugs (0)Regulon Drugs (89)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, RUPATADINE, DOXYLAMINE SUCCINATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, EBASTINE, CINNARIZINE, HYDROXYZINE, LORATADINE, LY2624803, PHENIRAMINE MALEATE, TRIPROLIDINE HYDROCHLORIDE, NERAMEXANE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, NERAMEXANE MESYLATE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, CETIRIZINE, METHDILAZINE |
| CMF-35123 | MDGA2 | down-regulates | hsa-mir-375 | represses | R-1944 | 61 | 11 | Drugs (87) Regulator Drugs (0)Regulon Drugs (87)PROMETHAZINE HYDROCHLORIDE, TRIPROLIDINE, LEVOCETIRIZINE DIHYDROCHLORIDE, KETOTIFEN FUMARATE, PYRILAMINE MALEATE, TRIPELENNAMINE, RUPATADINE, DOXYLAMINE SUCCINATE, MECLIZINE, BEPOTASTINE, BROMPHENIRAMINE, CLEMASTINE, OLOPATADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE, EPINASTINE HYDROCHLORIDE, TERFENADINE, CARBINOXAMINE MALEATE, DEXCHLORPHENIRAMINE, ORPHENADRINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, DEXBROMPHENIRAMINE, OLOPATADINE, ASTEMIZOLE, CHLORPHENIRAMINE, HISTAMINE, LEVOCABASTINE, DEXBROMPHENIRAMINE MALEATE, EBASTINE, CINNARIZINE, HYDROXYZINE, LORATADINE, LY2624803, PHENIRAMINE MALEATE, TRIPROLIDINE HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE, TRIMIPRAMINE, BUCLIZINE, EPINASTINE, ORPHENADRINE, KETOTIFEN, FEXOFENADINE, BILASTINE, CHLORPHENOXAMINE, LEVOCABASTINE HYDROCHLORIDE, DIBENZEPIN, PROMETHAZINE, AZELASTINE, DIPHENHYDRAMINE CITRATE, TOLAZOLINE, METHYLPROMAZINE, AZELASTINE HYDROCHLORIDE, ANTAZOLINE, CYCLIZINE, FEXOFENADINE HYDROCHLORIDE, DOXYLAMINE, CETIRIZINE HYDROCHLORIDE, DIPHENYLPYRALINE, ESMIRTAZAPINE MALEATE, LEVOCETIRIZINE, ACRIVASTINE, BEPOTASTINE BESYLATE, DIPHENHYDRAMINE, THENALIDINE, DIMENHYDRINATE, GSK-1004723, PYRILAMINE, ORPHENADRINE CITRATE, DEXCHLORPHENIRAMINE MALEATE, CYPROHEPTADINE, PHENIRAMINE, CLEMASTINE FUMARATE, BROMODIPHENHYDRAMINE, DIMETHINDENE, AZATADINE, ESMIRTAZAPINE, BROMPHENIRAMINE MALEATE, MECLIZINE HYDROCHLORIDE, METHAPYRILENE, EMEDASTINE, MIZOLASTINE, HYDROXYZINE PAMOATE, ALCAFTADINE, BETAHISTINE, CARBINOXAMINE, DESLORATADINE, CETIRIZINE, METHDILAZINE |