Regulator

Summary of regulator annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

hsa-mir-181d -

Function

Uniprot Browser

Entrez ID	EnsEMBL ID	Preferred Name	Uniprot ID
-		hsa-mir-181d

List of causal flows containing the regulator.

Causal Flows are statistically significant links between putative causal events (somatic mutations, copy number variations, chromosomal translocations, etc.) and the activity levels of regulators and regulons. In the causal flow, a mutation may causally activate or deactivate a downstream regulator which then might up- down-regulates a regulonthat contains genes with similar expression profiles and binding sites.

Causal Mechanistic Flows with hsa-mir-181d as Regulator

ID	Mutation	Role	Regulator	Role	Regulon	# downstream regulons	# diffexp regulons	Drugs
CMF-34168	PCDH9	up-regulates	hsa-mir-181d	represses	R-2104	31	6	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34169	PCDH9	up-regulates	hsa-mir-181d	represses	R-2224	31	6	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-34170	PCDH9	up-regulates	hsa-mir-181d	represses	R-2426	31	6	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) ATN-161, TAS0612, LANATOSIDE C, NIVOCASAN, NATALIZUMAB, FIRATEGRAST, EMRICASAN, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, VOLOCIXIMAB, RECOMBINANT HUMAN INTERLEUKIN-15, DESLANOSIDE, ISTAROXIME, ABITUZUMAB
CMF-34171	PCDH9	up-regulates	hsa-mir-181d	represses	R-576	31	6	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34172	PCDH9	up-regulates	hsa-mir-181d	represses	R-679	31	6	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34173	PCDH9	up-regulates	hsa-mir-181d	represses	R-3459	31	6	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-34555	TYK2	up-regulates	hsa-mir-181d	represses	R-2224	31	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-34556	TYK2	up-regulates	hsa-mir-181d	represses	R-1459	31	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-34557	TYK2	up-regulates	hsa-mir-181d	represses	R-1820	31	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-35290	ATRX	up-regulates	hsa-mir-181d	represses	R-61	31	28	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) PROBUCOL
CMF-35291	ATRX	up-regulates	hsa-mir-181d	represses	R-177	31	28	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-35292	ATRX	up-regulates	hsa-mir-181d	represses	R-2224	31	28	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-35293	ATRX	up-regulates	hsa-mir-181d	represses	R-2426	31	28	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) ATN-161, TAS0612, LANATOSIDE C, NIVOCASAN, NATALIZUMAB, FIRATEGRAST, EMRICASAN, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, VOLOCIXIMAB, RECOMBINANT HUMAN INTERLEUKIN-15, DESLANOSIDE, ISTAROXIME, ABITUZUMAB
CMF-35294	ATRX	up-regulates	hsa-mir-181d	represses	R-2431	31	28	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) ANG1005, PROBUCOL
CMF-35295	ATRX	up-regulates	hsa-mir-181d	represses	R-2446	31	28	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-35296	ATRX	up-regulates	hsa-mir-181d	represses	R-2451	31	28	Drugs (14) Regulator Drugs (0) Regulon Drugs (14) TAS0612, DASATINIB, LANATOSIDE C, VANDETANIB, TESEVATINIB, DIGOXIN, JI-101, ACETYLDIGITOXIN, TG100-801, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, REGORAFENIB, ISTAROXIME
CMF-35297	ATRX	up-regulates	hsa-mir-181d	represses	R-415	31	28	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-35298	ATRX	up-regulates	hsa-mir-181d	represses	R-576	31	28	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-35299	ATRX	up-regulates	hsa-mir-181d	represses	R-626	31	28	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-35300	ATRX	up-regulates	hsa-mir-181d	represses	R-651	31	28	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) ANG1005, PROBUCOL
CMF-35301	ATRX	up-regulates	hsa-mir-181d	represses	R-679	31	28	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-35302	ATRX	up-regulates	hsa-mir-181d	represses	R-738	31	28	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-35303	ATRX	up-regulates	hsa-mir-181d	represses	R-2798	31	28	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-35304	ATRX	up-regulates	hsa-mir-181d	represses	R-2940	31	28	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) TAS0612, OCRIPLASMIN
CMF-35305	ATRX	up-regulates	hsa-mir-181d	represses	R-3013	31	28	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-35306	ATRX	up-regulates	hsa-mir-181d	represses	R-970	31	28	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-35307	ATRX	up-regulates	hsa-mir-181d	represses	R-995	31	28	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-35308	ATRX	up-regulates	hsa-mir-181d	represses	R-1067	31	28	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-35309	ATRX	up-regulates	hsa-mir-181d	represses	R-3231	31	28	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-35310	ATRX	up-regulates	hsa-mir-181d	represses	R-3449	31	28	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-35311	ATRX	up-regulates	hsa-mir-181d	represses	R-3459	31	28	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-35312	ATRX	up-regulates	hsa-mir-181d	represses	R-3481	31	28	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) TAS0612, ANG1005, PROBUCOL, OCRIPLASMIN
CMF-35313	ATRX	up-regulates	hsa-mir-181d	represses	R-1459	31	28	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-35314	ATRX	up-regulates	hsa-mir-181d	represses	R-3604	31	28	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) PROBUCOL
CMF-35315	ATRX	up-regulates	hsa-mir-181d	represses	R-1645	31	28	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-35316	ATRX	up-regulates	hsa-mir-181d	represses	R-1820	31	28	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-35317	ATRX	up-regulates	hsa-mir-181d	represses	R-1853	31	28	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-35944	MAG	up-regulates	hsa-mir-181d	represses	R-1598	31	1	Drugs (52) Regulator Drugs (0) Regulon Drugs (52) TERODILINE, ACAMPROSATE CALCIUM, MIRDAMETINIB, AV-101, BINIMETINIB, MEMANTINE, DEXTROMETHORPHAN HYDROBROMIDE, COBIMETINIB FUMARATE, RO-4987655, MEMANTINE HYDROCHLORIDE, COBIMETINIB, ORPHENADRINE HYDROCHLORIDE, WX-554, AZD-8330, SELUMETINIB SULFATE, PIMASERTIB, SELUMETINIB, NERAMEXANE, KETAMINE, E-6201, DEXTROMETHORPHAN POLISTIREX, DEXTROMETHORPHAN, SAMALIZUMAB, ORPHENADRINE, TRAMETINIB, GABAPENTIN ENACARBIL, FELBAMATE, AMANTADINE HYDROCHLORIDE, PREGABALIN, RAPASTINEL, ATAGABALIN, GABAPENTIN, LANICEMINE, ACAMPROSATE, REFAMETINIB, RALFINAMIDE, BEPRIDIL, SULOCTIDIL, GW468816, NERAMEXANE MESYLATE, IMAGABALIN, ORPHENADRINE CITRATE, APIMOSTINEL, CI-1040, ESKETAMINE, INDANTADOL, ESKETAMINE HYDROCHLORIDE, AMANTADINE, TRAMETINIB DIMETHYL SULFOXIDE, KETAMINE HYDROCHLORIDE, TAK-733, AS-703988
CMF-36467	RP1	up-regulates	hsa-mir-181d	represses	R-2426	31	4	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) ATN-161, TAS0612, LANATOSIDE C, NIVOCASAN, NATALIZUMAB, FIRATEGRAST, EMRICASAN, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, VOLOCIXIMAB, RECOMBINANT HUMAN INTERLEUKIN-15, DESLANOSIDE, ISTAROXIME, ABITUZUMAB
CMF-36468	RP1	up-regulates	hsa-mir-181d	represses	R-626	31	4	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-36469	RP1	up-regulates	hsa-mir-181d	represses	R-3231	31	4	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-36470	RP1	up-regulates	hsa-mir-181d	represses	R-3459	31	4	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-38070	OR51F1	up-regulates	hsa-mir-181d	represses	R-1598	31	1	Drugs (52) Regulator Drugs (0) Regulon Drugs (52) TERODILINE, ACAMPROSATE CALCIUM, MIRDAMETINIB, AV-101, BINIMETINIB, MEMANTINE, DEXTROMETHORPHAN HYDROBROMIDE, COBIMETINIB FUMARATE, RO-4987655, MEMANTINE HYDROCHLORIDE, COBIMETINIB, ORPHENADRINE HYDROCHLORIDE, WX-554, AZD-8330, SELUMETINIB SULFATE, PIMASERTIB, SELUMETINIB, NERAMEXANE, KETAMINE, E-6201, DEXTROMETHORPHAN POLISTIREX, DEXTROMETHORPHAN, SAMALIZUMAB, ORPHENADRINE, TRAMETINIB, GABAPENTIN ENACARBIL, FELBAMATE, AMANTADINE HYDROCHLORIDE, PREGABALIN, RAPASTINEL, ATAGABALIN, GABAPENTIN, LANICEMINE, ACAMPROSATE, REFAMETINIB, RALFINAMIDE, BEPRIDIL, SULOCTIDIL, GW468816, NERAMEXANE MESYLATE, IMAGABALIN, ORPHENADRINE CITRATE, APIMOSTINEL, CI-1040, ESKETAMINE, INDANTADOL, ESKETAMINE HYDROCHLORIDE, AMANTADINE, TRAMETINIB DIMETHYL SULFOXIDE, KETAMINE HYDROCHLORIDE, TAK-733, AS-703988
CMF-38968	KCNH5	up-regulates	hsa-mir-181d	represses	R-2224	31	4	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-38969	KCNH5	up-regulates	hsa-mir-181d	represses	R-2446	31	4	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-38970	KCNH5	up-regulates	hsa-mir-181d	represses	R-1459	31	4	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-38971	KCNH5	up-regulates	hsa-mir-181d	represses	R-1820	31	4	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-39455	NF1	down-regulates	hsa-mir-181d	represses	R-2104	31	27	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-39456	NF1	down-regulates	hsa-mir-181d	represses	R-61	31	27	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) PROBUCOL
CMF-39457	NF1	down-regulates	hsa-mir-181d	represses	R-177	31	27	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-39458	NF1	down-regulates	hsa-mir-181d	represses	R-377	31	27	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-39459	NF1	down-regulates	hsa-mir-181d	represses	R-2426	31	27	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) ATN-161, TAS0612, LANATOSIDE C, NIVOCASAN, NATALIZUMAB, FIRATEGRAST, EMRICASAN, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, VOLOCIXIMAB, RECOMBINANT HUMAN INTERLEUKIN-15, DESLANOSIDE, ISTAROXIME, ABITUZUMAB
CMF-39460	NF1	down-regulates	hsa-mir-181d	represses	R-2431	31	27	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) ANG1005, PROBUCOL
CMF-39461	NF1	down-regulates	hsa-mir-181d	represses	R-2451	31	27	Drugs (14) Regulator Drugs (0) Regulon Drugs (14) TAS0612, DASATINIB, LANATOSIDE C, VANDETANIB, TESEVATINIB, DIGOXIN, JI-101, ACETYLDIGITOXIN, TG100-801, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, REGORAFENIB, ISTAROXIME
CMF-39462	NF1	down-regulates	hsa-mir-181d	represses	R-415	31	27	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-39463	NF1	down-regulates	hsa-mir-181d	represses	R-576	31	27	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-39464	NF1	down-regulates	hsa-mir-181d	represses	R-626	31	27	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-39465	NF1	down-regulates	hsa-mir-181d	represses	R-651	31	27	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) ANG1005, PROBUCOL
CMF-39466	NF1	down-regulates	hsa-mir-181d	represses	R-679	31	27	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-39467	NF1	down-regulates	hsa-mir-181d	represses	R-738	31	27	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-39468	NF1	down-regulates	hsa-mir-181d	represses	R-2798	31	27	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-39469	NF1	down-regulates	hsa-mir-181d	represses	R-2940	31	27	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) TAS0612, OCRIPLASMIN
CMF-39470	NF1	down-regulates	hsa-mir-181d	represses	R-3013	31	27	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-39471	NF1	down-regulates	hsa-mir-181d	represses	R-970	31	27	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-39472	NF1	down-regulates	hsa-mir-181d	represses	R-995	31	27	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-39473	NF1	down-regulates	hsa-mir-181d	represses	R-1067	31	27	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-39474	NF1	down-regulates	hsa-mir-181d	represses	R-3231	31	27	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-39475	NF1	down-regulates	hsa-mir-181d	represses	R-3449	31	27	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-39476	NF1	down-regulates	hsa-mir-181d	represses	R-3459	31	27	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-39477	NF1	down-regulates	hsa-mir-181d	represses	R-3481	31	27	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) TAS0612, ANG1005, PROBUCOL, OCRIPLASMIN
CMF-39478	NF1	down-regulates	hsa-mir-181d	represses	R-1459	31	27	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-39479	NF1	down-regulates	hsa-mir-181d	represses	R-3604	31	27	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) PROBUCOL
CMF-39480	NF1	down-regulates	hsa-mir-181d	represses	R-1645	31	27	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-39481	NF1	down-regulates	hsa-mir-181d	represses	R-1853	31	27	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-39891	IGFN1	up-regulates	hsa-mir-181d	represses	R-1598	31	1	Drugs (52) Regulator Drugs (0) Regulon Drugs (52) TERODILINE, ACAMPROSATE CALCIUM, MIRDAMETINIB, AV-101, BINIMETINIB, MEMANTINE, DEXTROMETHORPHAN HYDROBROMIDE, COBIMETINIB FUMARATE, RO-4987655, MEMANTINE HYDROCHLORIDE, COBIMETINIB, ORPHENADRINE HYDROCHLORIDE, WX-554, AZD-8330, SELUMETINIB SULFATE, PIMASERTIB, SELUMETINIB, NERAMEXANE, KETAMINE, E-6201, DEXTROMETHORPHAN POLISTIREX, DEXTROMETHORPHAN, SAMALIZUMAB, ORPHENADRINE, TRAMETINIB, GABAPENTIN ENACARBIL, FELBAMATE, AMANTADINE HYDROCHLORIDE, PREGABALIN, RAPASTINEL, ATAGABALIN, GABAPENTIN, LANICEMINE, ACAMPROSATE, REFAMETINIB, RALFINAMIDE, BEPRIDIL, SULOCTIDIL, GW468816, NERAMEXANE MESYLATE, IMAGABALIN, ORPHENADRINE CITRATE, APIMOSTINEL, CI-1040, ESKETAMINE, INDANTADOL, ESKETAMINE HYDROCHLORIDE, AMANTADINE, TRAMETINIB DIMETHYL SULFOXIDE, KETAMINE HYDROCHLORIDE, TAK-733, AS-703988
CMF-40272	EGR1	down-regulates	hsa-mir-181d	represses	R-61	31	4	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) PROBUCOL
CMF-40273	EGR1	down-regulates	hsa-mir-181d	represses	R-2446	31	4	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-40274	EGR1	down-regulates	hsa-mir-181d	represses	R-651	31	4	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) ANG1005, PROBUCOL
CMF-40275	EGR1	down-regulates	hsa-mir-181d	represses	R-1459	31	4	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-40534	IDH1	up-regulates	hsa-mir-181d	represses	R-2104	31	30	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-40535	IDH1	up-regulates	hsa-mir-181d	represses	R-61	31	30	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) PROBUCOL
CMF-40536	IDH1	up-regulates	hsa-mir-181d	represses	R-177	31	30	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-40537	IDH1	up-regulates	hsa-mir-181d	represses	R-2224	31	30	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-40538	IDH1	up-regulates	hsa-mir-181d	represses	R-377	31	30	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-40539	IDH1	up-regulates	hsa-mir-181d	represses	R-2426	31	30	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) ATN-161, TAS0612, LANATOSIDE C, NIVOCASAN, NATALIZUMAB, FIRATEGRAST, EMRICASAN, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, VOLOCIXIMAB, RECOMBINANT HUMAN INTERLEUKIN-15, DESLANOSIDE, ISTAROXIME, ABITUZUMAB
CMF-40540	IDH1	up-regulates	hsa-mir-181d	represses	R-2431	31	30	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) ANG1005, PROBUCOL
CMF-40541	IDH1	up-regulates	hsa-mir-181d	represses	R-2446	31	30	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-40542	IDH1	up-regulates	hsa-mir-181d	represses	R-2451	31	30	Drugs (14) Regulator Drugs (0) Regulon Drugs (14) TAS0612, DASATINIB, LANATOSIDE C, VANDETANIB, TESEVATINIB, DIGOXIN, JI-101, ACETYLDIGITOXIN, TG100-801, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, REGORAFENIB, ISTAROXIME
CMF-40543	IDH1	up-regulates	hsa-mir-181d	represses	R-415	31	30	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-40544	IDH1	up-regulates	hsa-mir-181d	represses	R-576	31	30	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-40545	IDH1	up-regulates	hsa-mir-181d	represses	R-626	31	30	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-40546	IDH1	up-regulates	hsa-mir-181d	represses	R-651	31	30	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) ANG1005, PROBUCOL
CMF-40547	IDH1	up-regulates	hsa-mir-181d	represses	R-679	31	30	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-40548	IDH1	up-regulates	hsa-mir-181d	represses	R-738	31	30	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-40549	IDH1	up-regulates	hsa-mir-181d	represses	R-2798	31	30	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-40550	IDH1	up-regulates	hsa-mir-181d	represses	R-2940	31	30	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) TAS0612, OCRIPLASMIN
CMF-40551	IDH1	up-regulates	hsa-mir-181d	represses	R-3013	31	30	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-40552	IDH1	up-regulates	hsa-mir-181d	represses	R-970	31	30	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-40553	IDH1	up-regulates	hsa-mir-181d	represses	R-995	31	30	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-40554	IDH1	up-regulates	hsa-mir-181d	represses	R-1067	31	30	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-40555	IDH1	up-regulates	hsa-mir-181d	represses	R-3231	31	30	Drugs (7) Regulator Drugs (0) Regulon Drugs (7) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-40556	IDH1	up-regulates	hsa-mir-181d	represses	R-3449	31	30	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-40557	IDH1	up-regulates	hsa-mir-181d	represses	R-3459	31	30	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-40558	IDH1	up-regulates	hsa-mir-181d	represses	R-3481	31	30	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) TAS0612, ANG1005, PROBUCOL, OCRIPLASMIN
CMF-40559	IDH1	up-regulates	hsa-mir-181d	represses	R-1459	31	30	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-40560	IDH1	up-regulates	hsa-mir-181d	represses	R-3604	31	30	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) PROBUCOL
CMF-40561	IDH1	up-regulates	hsa-mir-181d	represses	R-1645	31	30	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-40562	IDH1	up-regulates	hsa-mir-181d	represses	R-1820	31	30	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-40563	IDH1	up-regulates	hsa-mir-181d	represses	R-1853	31	30	Drugs (8) Regulator Drugs (0) Regulon Drugs (8) TAS0612, LANATOSIDE C, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, DESLANOSIDE, ISTAROXIME
CMF-42409	ANKRD36	down-regulates	hsa-mir-181d	represses	R-2224	31	5	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-42410	ANKRD36	down-regulates	hsa-mir-181d	represses	R-2426	31	5	Drugs (16) Regulator Drugs (0) Regulon Drugs (16) ATN-161, TAS0612, LANATOSIDE C, NIVOCASAN, NATALIZUMAB, FIRATEGRAST, EMRICASAN, DIGOXIN, ACETYLDIGITOXIN, OCRIPLASMIN, DIGITOXIN, VOLOCIXIMAB, RECOMBINANT HUMAN INTERLEUKIN-15, DESLANOSIDE, ISTAROXIME, ABITUZUMAB
CMF-42411	ANKRD36	down-regulates	hsa-mir-181d	represses	R-2446	31	5	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-42412	ANKRD36	down-regulates	hsa-mir-181d	represses	R-1459	31	5	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-42413	ANKRD36	down-regulates	hsa-mir-181d	represses	R-1820	31	5	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-42713	NPHS1	up-regulates	hsa-mir-181d	represses	R-1598	31	1	Drugs (52) Regulator Drugs (0) Regulon Drugs (52) TERODILINE, ACAMPROSATE CALCIUM, MIRDAMETINIB, AV-101, BINIMETINIB, MEMANTINE, DEXTROMETHORPHAN HYDROBROMIDE, COBIMETINIB FUMARATE, RO-4987655, MEMANTINE HYDROCHLORIDE, COBIMETINIB, ORPHENADRINE HYDROCHLORIDE, WX-554, AZD-8330, SELUMETINIB SULFATE, PIMASERTIB, SELUMETINIB, NERAMEXANE, KETAMINE, E-6201, DEXTROMETHORPHAN POLISTIREX, DEXTROMETHORPHAN, SAMALIZUMAB, ORPHENADRINE, TRAMETINIB, GABAPENTIN ENACARBIL, FELBAMATE, AMANTADINE HYDROCHLORIDE, PREGABALIN, RAPASTINEL, ATAGABALIN, GABAPENTIN, LANICEMINE, ACAMPROSATE, REFAMETINIB, RALFINAMIDE, BEPRIDIL, SULOCTIDIL, GW468816, NERAMEXANE MESYLATE, IMAGABALIN, ORPHENADRINE CITRATE, APIMOSTINEL, CI-1040, ESKETAMINE, INDANTADOL, ESKETAMINE HYDROCHLORIDE, AMANTADINE, TRAMETINIB DIMETHYL SULFOXIDE, KETAMINE HYDROCHLORIDE, TAK-733, AS-703988
CMF-43252	JHDM1D	up-regulates	hsa-mir-181d	represses	R-2224	31	4	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) BIVATUZUMAB
CMF-43253	JHDM1D	up-regulates	hsa-mir-181d	represses	R-651	31	4	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) ANG1005, PROBUCOL
CMF-43254	JHDM1D	up-regulates	hsa-mir-181d	represses	R-2940	31	4	Drugs (2) Regulator Drugs (0) Regulon Drugs (2) TAS0612, OCRIPLASMIN
CMF-43255	JHDM1D	up-regulates	hsa-mir-181d	represses	R-3481	31	4	Drugs (4) Regulator Drugs (0) Regulon Drugs (4) TAS0612, ANG1005, PROBUCOL, OCRIPLASMIN

hsa-mir-181d -

Function

Causal Mechanistic Flows with hsa-mir-181d as Regulator

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Regulon Drugs (52)