| CMF-03177 | WDR90 | up-regulates | SF1 | represses | R-2412 | 6 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-03179 | WDR90 | up-regulates | SF1 | activates | R-2411 | 6 | 3 | Drugs (78) Regulator Drugs (0)Regulon Drugs (78)POZIOTINIB, VARLITINIB, CUDC-101, LAPATINIB DITOSYLATE, GUANIDINE, DULIGOTUZUMAB, GUANIDINE HYDROCHLORIDE, FUTUXIMAB, NAZARTINIB, MP-412, NIMOTUZUMAB, TOMUZOTUXIMAB, ROCILETINIB, CANERTINIB DIHYDROCHLORIDE, NERATINIB MALEATE, AMIFAMPRIDINE PHOSPHATE, MOBOCERTINIB, GEFITINIB, CEP-32496, LAPATINIB, ALMONERTINIB, BRIGATINIB, EPITINIB, SAPITINIB, NERATINIB, BMS-690514, PELITINIB, AC-480, DALFAMPRIDINE, PANITUMUMAB, DACOMITINIB, ABIVERTINIB, KBP5209, TARLOXOTINIB, ABIVERTINIB MALEATE, DEPATUXIZUMAB, ALFLUTINIB, SIMOTINIB, PF-06459988, THELIATINIB, VANDETANIB, ALLITINIB, DEPATUXIZUMAB MAFODOTIN, OLMUTINIB, TEDISAMIL, CLN-081, NERISPIRDINE, AZD-3759, OSIMERTINIB, MAB-425, CANERTINIB, BDTX189, AMIVANTAMAB, AMIFAMPRIDINE, GC1118, JNJ-26483327, TESEVATINIB, NECITUMUMAB, MATUZUMAB, ZALUTUMUMAB, FALNIDAMOL, ERLOTINIB, AFATINIB DIMALEATE, IMGATUZUMAB, AFATINIB, CETUXIMAB, RINDOPEPIMUT, NAQUOTINIB, OCRIPLASMIN, MDX-447, AEE-788, PYROTINIB, ERLOTINIB HYDROCHLORIDE, SKLB1028, OSIMERTINIB MESYLATE, TAK-285, MAVELERTINIB, ICOTINIB |
| CMF-07158 | ATRX | up-regulates | SF1 | represses | R-2412 | 6 | 2 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-09288 | RP1 | up-regulates | SF1 | represses | R-2412 | 6 | 1 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-15194 | ERCC6 | down-regulates | SF1 | activates | R-2411 | 6 | 1 | Drugs (78) Regulator Drugs (0)Regulon Drugs (78)POZIOTINIB, VARLITINIB, CUDC-101, LAPATINIB DITOSYLATE, GUANIDINE, DULIGOTUZUMAB, GUANIDINE HYDROCHLORIDE, FUTUXIMAB, NAZARTINIB, MP-412, NIMOTUZUMAB, TOMUZOTUXIMAB, ROCILETINIB, CANERTINIB DIHYDROCHLORIDE, NERATINIB MALEATE, AMIFAMPRIDINE PHOSPHATE, MOBOCERTINIB, GEFITINIB, CEP-32496, LAPATINIB, ALMONERTINIB, BRIGATINIB, EPITINIB, SAPITINIB, NERATINIB, BMS-690514, PELITINIB, AC-480, DALFAMPRIDINE, PANITUMUMAB, DACOMITINIB, ABIVERTINIB, KBP5209, TARLOXOTINIB, ABIVERTINIB MALEATE, DEPATUXIZUMAB, ALFLUTINIB, SIMOTINIB, PF-06459988, THELIATINIB, VANDETANIB, ALLITINIB, DEPATUXIZUMAB MAFODOTIN, OLMUTINIB, TEDISAMIL, CLN-081, NERISPIRDINE, AZD-3759, OSIMERTINIB, MAB-425, CANERTINIB, BDTX189, AMIVANTAMAB, AMIFAMPRIDINE, GC1118, JNJ-26483327, TESEVATINIB, NECITUMUMAB, MATUZUMAB, ZALUTUMUMAB, FALNIDAMOL, ERLOTINIB, AFATINIB DIMALEATE, IMGATUZUMAB, AFATINIB, CETUXIMAB, RINDOPEPIMUT, NAQUOTINIB, OCRIPLASMIN, MDX-447, AEE-788, PYROTINIB, ERLOTINIB HYDROCHLORIDE, SKLB1028, OSIMERTINIB MESYLATE, TAK-285, MAVELERTINIB, ICOTINIB |
| CMF-18900 | INPP5J | up-regulates | SF1 | represses | R-2412 | 6 | 1 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-22946 | IDH1 | up-regulates | SF1 | represses | R-2412 | 6 | 5 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-24079 | TP53 | up-regulates | SF1 | represses | R-2412 | 6 | 3 | Drugs (0) Regulator Drugs (0)Regulon Drugs (0) |
| CMF-31596 | EGF_RECEPTOR_SIGNALING_PATHWAY | up-regulates | SF1 | activates | R-2411 | 6 | 1 | Drugs (78) Regulator Drugs (0)Regulon Drugs (78)POZIOTINIB, VARLITINIB, CUDC-101, LAPATINIB DITOSYLATE, GUANIDINE, DULIGOTUZUMAB, GUANIDINE HYDROCHLORIDE, FUTUXIMAB, NAZARTINIB, MP-412, NIMOTUZUMAB, TOMUZOTUXIMAB, ROCILETINIB, CANERTINIB DIHYDROCHLORIDE, NERATINIB MALEATE, AMIFAMPRIDINE PHOSPHATE, MOBOCERTINIB, GEFITINIB, CEP-32496, LAPATINIB, ALMONERTINIB, BRIGATINIB, EPITINIB, SAPITINIB, NERATINIB, BMS-690514, PELITINIB, AC-480, DALFAMPRIDINE, PANITUMUMAB, DACOMITINIB, ABIVERTINIB, KBP5209, TARLOXOTINIB, ABIVERTINIB MALEATE, DEPATUXIZUMAB, ALFLUTINIB, SIMOTINIB, PF-06459988, THELIATINIB, VANDETANIB, ALLITINIB, DEPATUXIZUMAB MAFODOTIN, OLMUTINIB, TEDISAMIL, CLN-081, NERISPIRDINE, AZD-3759, OSIMERTINIB, MAB-425, CANERTINIB, BDTX189, AMIVANTAMAB, AMIFAMPRIDINE, GC1118, JNJ-26483327, TESEVATINIB, NECITUMUMAB, MATUZUMAB, ZALUTUMUMAB, FALNIDAMOL, ERLOTINIB, AFATINIB DIMALEATE, IMGATUZUMAB, AFATINIB, CETUXIMAB, RINDOPEPIMUT, NAQUOTINIB, OCRIPLASMIN, MDX-447, AEE-788, PYROTINIB, ERLOTINIB HYDROCHLORIDE, SKLB1028, OSIMERTINIB MESYLATE, TAK-285, MAVELERTINIB, ICOTINIB |
| CMF-32840 | E_CADHERIN_SIGNALING_IN_KERATINOCYTES | up-regulates | SF1 | activates | R-2411 | 6 | 1 | Drugs (78) Regulator Drugs (0)Regulon Drugs (78)POZIOTINIB, VARLITINIB, CUDC-101, LAPATINIB DITOSYLATE, GUANIDINE, DULIGOTUZUMAB, GUANIDINE HYDROCHLORIDE, FUTUXIMAB, NAZARTINIB, MP-412, NIMOTUZUMAB, TOMUZOTUXIMAB, ROCILETINIB, CANERTINIB DIHYDROCHLORIDE, NERATINIB MALEATE, AMIFAMPRIDINE PHOSPHATE, MOBOCERTINIB, GEFITINIB, CEP-32496, LAPATINIB, ALMONERTINIB, BRIGATINIB, EPITINIB, SAPITINIB, NERATINIB, BMS-690514, PELITINIB, AC-480, DALFAMPRIDINE, PANITUMUMAB, DACOMITINIB, ABIVERTINIB, KBP5209, TARLOXOTINIB, ABIVERTINIB MALEATE, DEPATUXIZUMAB, ALFLUTINIB, SIMOTINIB, PF-06459988, THELIATINIB, VANDETANIB, ALLITINIB, DEPATUXIZUMAB MAFODOTIN, OLMUTINIB, TEDISAMIL, CLN-081, NERISPIRDINE, AZD-3759, OSIMERTINIB, MAB-425, CANERTINIB, BDTX189, AMIVANTAMAB, AMIFAMPRIDINE, GC1118, JNJ-26483327, TESEVATINIB, NECITUMUMAB, MATUZUMAB, ZALUTUMUMAB, FALNIDAMOL, ERLOTINIB, AFATINIB DIMALEATE, IMGATUZUMAB, AFATINIB, CETUXIMAB, RINDOPEPIMUT, NAQUOTINIB, OCRIPLASMIN, MDX-447, AEE-788, PYROTINIB, ERLOTINIB HYDROCHLORIDE, SKLB1028, OSIMERTINIB MESYLATE, TAK-285, MAVELERTINIB, ICOTINIB |
| CMF-33383 | ERBB1_DOWNSTREAM_SIGNALING | up-regulates | SF1 | activates | R-2411 | 6 | 1 | Drugs (78) Regulator Drugs (0)Regulon Drugs (78)POZIOTINIB, VARLITINIB, CUDC-101, LAPATINIB DITOSYLATE, GUANIDINE, DULIGOTUZUMAB, GUANIDINE HYDROCHLORIDE, FUTUXIMAB, NAZARTINIB, MP-412, NIMOTUZUMAB, TOMUZOTUXIMAB, ROCILETINIB, CANERTINIB DIHYDROCHLORIDE, NERATINIB MALEATE, AMIFAMPRIDINE PHOSPHATE, MOBOCERTINIB, GEFITINIB, CEP-32496, LAPATINIB, ALMONERTINIB, BRIGATINIB, EPITINIB, SAPITINIB, NERATINIB, BMS-690514, PELITINIB, AC-480, DALFAMPRIDINE, PANITUMUMAB, DACOMITINIB, ABIVERTINIB, KBP5209, TARLOXOTINIB, ABIVERTINIB MALEATE, DEPATUXIZUMAB, ALFLUTINIB, SIMOTINIB, PF-06459988, THELIATINIB, VANDETANIB, ALLITINIB, DEPATUXIZUMAB MAFODOTIN, OLMUTINIB, TEDISAMIL, CLN-081, NERISPIRDINE, AZD-3759, OSIMERTINIB, MAB-425, CANERTINIB, BDTX189, AMIVANTAMAB, AMIFAMPRIDINE, GC1118, JNJ-26483327, TESEVATINIB, NECITUMUMAB, MATUZUMAB, ZALUTUMUMAB, FALNIDAMOL, ERLOTINIB, AFATINIB DIMALEATE, IMGATUZUMAB, AFATINIB, CETUXIMAB, RINDOPEPIMUT, NAQUOTINIB, OCRIPLASMIN, MDX-447, AEE-788, PYROTINIB, ERLOTINIB HYDROCHLORIDE, SKLB1028, OSIMERTINIB MESYLATE, TAK-285, MAVELERTINIB, ICOTINIB |
| CMF-33841 | N_CADHERIN_SIGNALING_EVENTS | up-regulates | SF1 | activates | R-2411 | 6 | 1 | Drugs (78) Regulator Drugs (0)Regulon Drugs (78)POZIOTINIB, VARLITINIB, CUDC-101, LAPATINIB DITOSYLATE, GUANIDINE, DULIGOTUZUMAB, GUANIDINE HYDROCHLORIDE, FUTUXIMAB, NAZARTINIB, MP-412, NIMOTUZUMAB, TOMUZOTUXIMAB, ROCILETINIB, CANERTINIB DIHYDROCHLORIDE, NERATINIB MALEATE, AMIFAMPRIDINE PHOSPHATE, MOBOCERTINIB, GEFITINIB, CEP-32496, LAPATINIB, ALMONERTINIB, BRIGATINIB, EPITINIB, SAPITINIB, NERATINIB, BMS-690514, PELITINIB, AC-480, DALFAMPRIDINE, PANITUMUMAB, DACOMITINIB, ABIVERTINIB, KBP5209, TARLOXOTINIB, ABIVERTINIB MALEATE, DEPATUXIZUMAB, ALFLUTINIB, SIMOTINIB, PF-06459988, THELIATINIB, VANDETANIB, ALLITINIB, DEPATUXIZUMAB MAFODOTIN, OLMUTINIB, TEDISAMIL, CLN-081, NERISPIRDINE, AZD-3759, OSIMERTINIB, MAB-425, CANERTINIB, BDTX189, AMIVANTAMAB, AMIFAMPRIDINE, GC1118, JNJ-26483327, TESEVATINIB, NECITUMUMAB, MATUZUMAB, ZALUTUMUMAB, FALNIDAMOL, ERLOTINIB, AFATINIB DIMALEATE, IMGATUZUMAB, AFATINIB, CETUXIMAB, RINDOPEPIMUT, NAQUOTINIB, OCRIPLASMIN, MDX-447, AEE-788, PYROTINIB, ERLOTINIB HYDROCHLORIDE, SKLB1028, OSIMERTINIB MESYLATE, TAK-285, MAVELERTINIB, ICOTINIB |