Regulator

Summary of regulator annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

MEOX2 - mesenchyme homeobox 2

Function

Mesodermal transcription factor that plays a key role in somitogenesis and somitogenesis and limb muscle differentiation (By similarity). Required during limb development for normal appendicular muscle formation and for the normal regulation of myogenic genes (By similarity). May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle (By similarity). Also acts as a negative regulator of angiogenesis (PubMed:17074759, PubMed:20516212, PubMed:22206000). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation (PubMed:17074759, PubMed:22206000). While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000). Together with TCF15, regulates transcription in heart endothelial cells to regulate fatty acid transport across heart endothelial cells (By similarity).

Uniprot Browser

Entrez ID	EnsEMBL ID	Preferred Name	Uniprot ID
4223	ENSG00000106511	MEOX2	P50222

List of causal flows containing the regulator.

Causal Flows are statistically significant links between putative causal events (somatic mutations, copy number variations, chromosomal translocations, etc.) and the activity levels of regulators and regulons. In the causal flow, a mutation may causally activate or deactivate a downstream regulator which then might up- down-regulates a regulonthat contains genes with similar expression profiles and binding sites.

Causal Mechanistic Flows with ENSG00000106511 as Regulator

ID	Mutation	Role	Regulator	Role	Regulon	# downstream regulons	# diffexp regulons	Drugs
CMF-00616	HMCN1	up-regulates	MEOX2	activates	R-2196	14	5	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-00617	HMCN1	up-regulates	MEOX2	activates	R-2195	14	5	Drugs (24) Regulator Drugs (0) Regulon Drugs (24) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-00618	HMCN1	up-regulates	MEOX2	activates	R-2199	14	5	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-00619	HMCN1	up-regulates	MEOX2	activates	R-2203	14	5	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-00620	HMCN1	up-regulates	MEOX2	activates	R-2202	14	5	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-01299	KIAA1210	up-regulates	MEOX2	represses	R-2193	14	2	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) ELX-02, ATALUREN, MT-3724
CMF-01326	OR2H1	down-regulates	MEOX2	activates	R-2196	14	1	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-02750	BCAM	down-regulates	MEOX2	activates	R-2196	14	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-02752	BCAM	down-regulates	MEOX2	activates	R-2199	14	3	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-02881	SRRM2	up-regulates	MEOX2	activates	R-2196	14	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-02883	SRRM2	up-regulates	MEOX2	activates	R-2202	14	3	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-02912	CDK13	up-regulates	MEOX2	activates	R-2202	14	1	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-03135	EEF1A1	up-regulates	MEOX2	activates	R-2196	14	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-03137	EEF1A1	up-regulates	MEOX2	activates	R-2203	14	3	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-03338	ENPP2	up-regulates	MEOX2	activates	R-2196	14	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-03340	ENPP2	up-regulates	MEOX2	activates	R-2202	14	3	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-03510	SCN1A	up-regulates	MEOX2	activates	R-2195	14	2	Drugs (24) Regulator Drugs (0) Regulon Drugs (24) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-03511	SCN1A	up-regulates	MEOX2	activates	R-2203	14	2	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-03833	DSP	up-regulates	MEOX2	activates	R-2199	14	8	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-03835	DSP	up-regulates	MEOX2	activates	R-2202	14	8	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-04755	ADAMTS20	up-regulates	MEOX2	activates	R-2203	14	1	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-04987	PRR23C	down-regulates	MEOX2	activates	R-2196	14	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-05292	PCSK6	up-regulates	MEOX2	activates	R-2195	14	3	Drugs (24) Regulator Drugs (0) Regulon Drugs (24) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-05294	PCSK6	up-regulates	MEOX2	activates	R-2203	14	3	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-05456	KIAA1549	up-regulates	MEOX2	activates	R-2203	14	3	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-05873	ZNF813	up-regulates	MEOX2	activates	R-2195	14	1	Drugs (24) Regulator Drugs (0) Regulon Drugs (24) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-06481	LGSN	up-regulates	MEOX2	represses	R-2193	14	3	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) ELX-02, ATALUREN, MT-3724
CMF-06886	ATRX	down-regulates	MEOX2	activates	R-2196	14	10	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-06887	ATRX	down-regulates	MEOX2	activates	R-2195	14	10	Drugs (24) Regulator Drugs (0) Regulon Drugs (24) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-06889	ATRX	down-regulates	MEOX2	represses	R-2193	14	10	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) ELX-02, ATALUREN, MT-3724
CMF-06890	ATRX	down-regulates	MEOX2	activates	R-2199	14	10	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-06892	ATRX	down-regulates	MEOX2	activates	R-2203	14	10	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-06893	ATRX	down-regulates	MEOX2	activates	R-2202	14	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-07226	RELN	up-regulates	MEOX2	activates	R-2199	14	1	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-07284	NOD2	up-regulates	MEOX2	activates	R-2199	14	4	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-07285	NOD2	up-regulates	MEOX2	activates	R-2203	14	4	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-07286	NOD2	up-regulates	MEOX2	activates	R-2202	14	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-08190	TPO	up-regulates	MEOX2	activates	R-2202	14	1	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-09325	KIAA1409	up-regulates	MEOX2	represses	R-2193	14	2	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) ELX-02, ATALUREN, MT-3724
CMF-10526	LRBA	up-regulates	MEOX2	activates	R-2196	14	5	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-10527	LRBA	up-regulates	MEOX2	activates	R-2195	14	5	Drugs (24) Regulator Drugs (0) Regulon Drugs (24) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-10529	LRBA	up-regulates	MEOX2	activates	R-2203	14	5	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-10761	TMEM132B	up-regulates	MEOX2	activates	R-2196	14	2	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-11263	OR5W2	up-regulates	MEOX2	activates	R-2195	14	2	Drugs (24) Regulator Drugs (0) Regulon Drugs (24) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-11264	OR5W2	up-regulates	MEOX2	activates	R-2202	14	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-11665	AHR	up-regulates	MEOX2	activates	R-2203	14	2	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-12422	HSPG2	down-regulates	MEOX2	represses	R-2193	14	2	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) ELX-02, ATALUREN, MT-3724
CMF-12498	LAMB3	up-regulates	MEOX2	activates	R-2196	14	4	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-12756	RAG2	up-regulates	MEOX2	activates	R-2202	14	1	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-14353	SIPA1L1	up-regulates	MEOX2	activates	R-2195	14	2	Drugs (24) Regulator Drugs (0) Regulon Drugs (24) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-15654	DCHS2	up-regulates	MEOX2	activates	R-2203	14	2	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-16428	SUSD5	up-regulates	MEOX2	activates	R-2196	14	4	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-16430	SUSD5	up-regulates	MEOX2	activates	R-2199	14	4	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-16431	SUSD5	up-regulates	MEOX2	activates	R-2202	14	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-17468	OR5L2	up-regulates	MEOX2	activates	R-2203	14	3	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-18124	ZFP42	up-regulates	MEOX2	activates	R-2196	14	1	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-18972	CLEC14A	up-regulates	MEOX2	activates	R-2203	14	1	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-19366	NF1	up-regulates	MEOX2	activates	R-2196	14	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-19367	NF1	up-regulates	MEOX2	activates	R-2195	14	3	Drugs (24) Regulator Drugs (0) Regulon Drugs (24) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-19368	NF1	up-regulates	MEOX2	activates	R-2202	14	3	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-20900	CD3EAP	up-regulates	MEOX2	activates	R-2202	14	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-21355	GRIK3	up-regulates	MEOX2	activates	R-2203	14	3	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-21356	GRIK3	up-regulates	MEOX2	activates	R-2202	14	3	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-22539	IDH1	down-regulates	MEOX2	activates	R-2196	14	10	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-22540	IDH1	down-regulates	MEOX2	activates	R-2195	14	10	Drugs (24) Regulator Drugs (0) Regulon Drugs (24) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-22542	IDH1	down-regulates	MEOX2	represses	R-2193	14	10	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) ELX-02, ATALUREN, MT-3724
CMF-22543	IDH1	down-regulates	MEOX2	activates	R-2199	14	10	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-22545	IDH1	down-regulates	MEOX2	activates	R-2203	14	10	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-22546	IDH1	down-regulates	MEOX2	activates	R-2202	14	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-23445	SRCAP	up-regulates	MEOX2	activates	R-2202	14	1	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-23793	TP53	down-regulates	MEOX2	activates	R-2196	14	10	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-23794	TP53	down-regulates	MEOX2	activates	R-2195	14	10	Drugs (24) Regulator Drugs (0) Regulon Drugs (24) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-23798	TP53	down-regulates	MEOX2	activates	R-2199	14	10	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-23800	TP53	down-regulates	MEOX2	activates	R-2203	14	10	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-23801	TP53	down-regulates	MEOX2	activates	R-2202	14	10	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-24599	THADA	down-regulates	MEOX2	activates	R-2196	14	4	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-24601	THADA	down-regulates	MEOX2	activates	R-2202	14	4	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-24791	HIST1H2BE	up-regulates	MEOX2	activates	R-2196	14	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-24793	HIST1H2BE	up-regulates	MEOX2	activates	R-2202	14	3	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-25198	ZNF534	up-regulates	MEOX2	activates	R-2196	14	1	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-25436	PCDHGB3	up-regulates	MEOX2	activates	R-2196	14	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-25437	PCDHGB3	up-regulates	MEOX2	represses	R-2193	14	3	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) ELX-02, ATALUREN, MT-3724
CMF-25662	MYO18B	down-regulates	MEOX2	represses	R-2193	14	1	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) ELX-02, ATALUREN, MT-3724
CMF-26319	CHGB	up-regulates	MEOX2	activates	R-2203	14	2	Drugs (0) Regulator Drugs (0) Regulon Drugs (0)
CMF-26481	EGFR	up-regulates	MEOX2	represses	R-2193	14	4	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) ELX-02, ATALUREN, MT-3724
CMF-26631	C5AR1	up-regulates	MEOX2	activates	R-2195	14	1	Drugs (24) Regulator Drugs (0) Regulon Drugs (24) TRELAGLIPTIN SUCCINATE, TD-139, VILDAGLIPTIN, DAVANAT, ALOGLIPTIN BENZOATE, SAXAGLIPTIN, ANAGLIPTIN, ENIBARCIMAB, TENELIGLIPTIN, CARMEGLIPTIN, BEGELOMAB, OMARIGLIPTIN, SAXAGLIPTIN HYDROCHLORIDE, GEMIGLIPTIN, BISEGLIPTIN, SITAGLIPTIN, DUTOGLIPTIN, EVOGLIPTIN, ALOGLIPTIN, BELAPECTIN, LINAGLIPTIN, TRELAGLIPTIN, GOSOGLIPTIN, SITAGLIPTIN PHOSPHATE
CMF-26852	VAV1	up-regulates	MEOX2	activates	R-2202	14	2	Drugs (5) Regulator Drugs (0) Regulon Drugs (5) ELIGLUSTAT, ELIGLUSTAT TARTRATE, MIGLUSTAT, SATRALIZUMAB, LUCERASTAT
CMF-31239	SHP2_SIGNALING	up-regulates	MEOX2	activates	R-2196	14	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-31241	SHP2_SIGNALING	up-regulates	MEOX2	activates	R-2199	14	3	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-31368	ANGIOPOIETIN_RECEPTOR_TIE2_MEDIATED_SIGNALING	up-regulates	MEOX2	activates	R-2196	14	5	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-31372	ANGIOPOIETIN_RECEPTOR_TIE2_MEDIATED_SIGNALING	up-regulates	MEOX2	activates	R-2199	14	5	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-31461	SIGNALING_EVENTS_MEDIATED_BY_TCPTP	up-regulates	MEOX2	activates	R-2196	14	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-31463	SIGNALING_EVENTS_MEDIATED_BY_TCPTP	up-regulates	MEOX2	activates	R-2199	14	3	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-31535	EGF_RECEPTOR_SIGNALING_PATHWAY	up-regulates	MEOX2	activates	R-2196	14	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-31537	EGF_RECEPTOR_SIGNALING_PATHWAY	up-regulates	MEOX2	activates	R-2199	14	3	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-31811	SIGNALING_EVENTS_MEDIATED_BY_VEGFR1_AND_VEGFR2	up-regulates	MEOX2	activates	R-2196	14	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-31813	SIGNALING_EVENTS_MEDIATED_BY_VEGFR1_AND_VEGFR2	up-regulates	MEOX2	activates	R-2199	14	3	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-32033	SIGNALING_EVENTS_MEDIATED_BY_HEPATOCYTE_GFR	up-regulates	MEOX2	activates	R-2196	14	5	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-32035	SIGNALING_EVENTS_MEDIATED_BY_HEPATOCYTE_GFR	up-regulates	MEOX2	represses	R-2193	14	5	Drugs (3) Regulator Drugs (0) Regulon Drugs (3) ELX-02, ATALUREN, MT-3724
CMF-32037	SIGNALING_EVENTS_MEDIATED_BY_HEPATOCYTE_GFR	up-regulates	MEOX2	activates	R-2199	14	5	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-32097	A6B1_AND_A6B4_INTEGRIN_SIGNALING	up-regulates	MEOX2	activates	R-2196	14	4	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-32100	A6B1_AND_A6B4_INTEGRIN_SIGNALING	up-regulates	MEOX2	activates	R-2199	14	4	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-32800	E_CADHERIN_SIGNALING_IN_KERATINOCYTES	up-regulates	MEOX2	activates	R-2196	14	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-32802	E_CADHERIN_SIGNALING_IN_KERATINOCYTES	up-regulates	MEOX2	activates	R-2199	14	3	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-33329	ERBB1_DOWNSTREAM_SIGNALING	up-regulates	MEOX2	activates	R-2196	14	4	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-33332	ERBB1_DOWNSTREAM_SIGNALING	up-regulates	MEOX2	activates	R-2199	14	4	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN
CMF-33798	SIGNALING_EVENTS_MEDIATED_BY_PTP1B	up-regulates	MEOX2	activates	R-2196	14	3	Drugs (1) Regulator Drugs (0) Regulon Drugs (1) OCRIPLASMIN
CMF-33800	SIGNALING_EVENTS_MEDIATED_BY_PTP1B	up-regulates	MEOX2	activates	R-2199	14	3	Drugs (59) Regulator Drugs (0) Regulon Drugs (59) IBUPROFEN, PIRPROFEN, PHENYLBUTAZONE, ACETAMINOPHEN, OXYPHENBUTAZONE, BROMFENAC SODIUM, OLSALAZINE, LORNOXICAM, FLURBIPROFEN, DIPYRONE, FENOPROFEN, ANTIPYRINE, NAPROXEN SODIUM, DEXKETOPROFEN, ASPIRIN, ESFLURBIPROFEN, ALOXIPRIN, INDOPROFEN, KETOROLAC, INDOMETHACIN SODIUM, BENZYDAMINE, NAPROXEN, DICLOFENAC EPOLAMINE, FENOPROFEN CALCIUM, MECLOFENAMIC ACID, OLSALAZINE SODIUM, APAZONE, MESALAMINE, ACEMETACIN, IBUPROFEN SODIUM, BALSALAZIDE DISODIUM, NEPAFENAC, DICLOFENAC POTASSIUM, IBUPROFEN LYSINE, PIROXICAM, SUPROFEN, SULFASALAZINE, MECLOFENAMATE SODIUM, LOXOPROFEN, DICLOFENAC SODIUM, BENZYDAMINE HYDROCHLORIDE, TOLMETIN SODIUM, KETOROLAC TROMETHAMINE, ALCLOFENAC, DEXIBUPROFEN, SULINDAC, KETOPROFEN, BALSALAZIDE, NAPROXCINOD, TOLMETIN, DICLOFENAC, BISMUTH SUBSALICYLATE, MEFENAMIC ACID, GLAFENINE, DIFLUNISAL, BROMFENAC, NAPROXEN ETEMESIL, INDOMETHACIN, OXAPROZIN

MEOX2 - mesenchyme homeobox 2

Function

Causal Mechanistic Flows with ENSG00000106511 as Regulator

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