Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
RGS19 - regulator of G protein signaling 19
Function
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 10287 | ENSG00000171700 | RGS19 | P49795 |
Gene Regulons
List of regulons containing the gene.
A gene can be associated with multiple causal flows as a member of multiple regulons