Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

PDIA3 - protein disulfide isomerase family A member 3

Function

Disulfide isomerase which catalyzes the formation, isomerization, and reduction or oxidation of disulfide bonds (PubMed:7487104, PubMed:27897272). Associates with calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (PubMed:27897272). Association with calcitriol does not affect its enzymatic activity (PubMed:27897272).

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
2923 ENSG00000167004 PDIA3 P30101

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1067Pr-1311149
R-113Pr-1381110
R-1304Pr-1311122
R-1448Pr-131111
R-160Pr-1311110
R-2078Pr-1311120
R-2451Pr-1311168
R-2841Pr-1311110
R-2883Pr-1311129
R-3013Pr-1311150
R-3072Pr-1311141
R-3231Pr-1311153
R-377Pr-1311122
R-415Pr-1311139
R-970Pr-1311156