Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

PCSK1 - proprotein convertase subtilisin/kexin type 1

Function

Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
5122 ENSG00000175426 PCSK1 P29120

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1042Pr-6115
R-142Pr-6118
R-2195Pr-61112
R-2480Pr-6112
R-2761Pr-61120
R-3378Pr-6115
R-3550Pr-6117
R-629Pr-61110
R-649Pr-61113
R-704Pr-6117