Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

NRIP1 - nuclear receptor interacting protein 1

Function

Modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1. Also modulates transcriptional repression by nuclear hormone receptors. Positive regulator of the circadian clock gene expression: stimulates transcription of BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC. Involved in the regulation of ovarian function (By similarity). Plays a role in renal development (PubMed:28381549).

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
8204 ENSG00000180530 NRIP1 P48552

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1460Pr-137113
R-1997Pr-1311112
R-2356Pr-171110
R-2963Pr-171122
R-2989Pr-17112
R-3006Pr-171115
R-3012Pr-171120
R-3038Pr-171111
R-3052Pr-131116
R-3063Pr-171111
R-622Pr-1311112
R-718Pr-1311113
R-794Pr-171110