Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

LOX - lysyl oxidase

Function

Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin (PubMed:26838787). Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture (By similarity).

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
4015 ENSG00000113083 LOX P28300

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1042Pr-6115
R-142Pr-6118
R-1487Pr-61111
R-1681Pr-61112
R-1834Pr-6118
R-1911Pr-6116
R-2056Pr-61112
R-2480Pr-6112
R-2761Pr-61120
R-3174Pr-61117
R-3378Pr-6115
R-3493Pr-6113
R-3550Pr-6117
R-379Pr-61110
R-629Pr-61110
R-649Pr-61113
R-704Pr-6117