Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

CYB5R4 - cytochrome b5 reductase 4

Function

NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
51167 ENSG00000065615 CYB5R4 Q7L1T6

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-173Pr-71134
R-192Pr-71174
R-257Pr-71156
R-275Pr-71166
R-326Pr-71129
R-370Pr-71130
R-93Pr-71117