Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

CCDC28B - coiled-coil domain containing 28B

Function

Involved in ciliogenesis. Regulates cilia length through its interaction with MAPKAP1/SIN1 but independently of mTORC2 complex. Modulates mTORC2 complex assembly and function, possibly enhances AKT1 phosphorylation. Does not seem to modulate assembly and function of mTORC1 complex.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
79140 ENSG00000160050 CCDC28B Q9BUN5

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-1373Pr-1201115
R-1601Pr-120113
R-913Pr-68117
R-94Pr-68114