Gene

Gene details

Summary of gene annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

ALOX5AP - arachidonate 5-lipoxygenase activating protein

Function

Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.

Uniprot Browser
Entrez IDEnsEMBL IDPreferred NameUniprot ID
241 ENSG00000132965 ALOX5AP P20292

Gene Regulons

List of regulons containing the gene.

A gene can be associated with multiple causal flows as a member of multiple regulons

RegulonProgram# genes# regulators# causal flows
R-158Pr-71159
R-173Pr-71134
R-1876Pr-7113
R-1902Pr-71121
R-207Pr-71144
R-257Pr-71156
R-3032Pr-71127
R-326Pr-71129
R-3371Pr-7117
R-356Pr-71157
R-370Pr-71130
R-413Pr-71123
R-438Pr-71144
R-444Pr-7116