Gene details
Summary of gene annotations and link-out to annotation databases
Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.
ADAM12 - ADAM metallopeptidase domain 12
Function
Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors (By similarity).
Uniprot Browser| Entrez ID | EnsEMBL ID | Preferred Name | Uniprot ID |
|---|---|---|---|
| 8038 | ENSG00000148848 | ADAM12 | O43184 |
Gene Regulons
List of regulons containing the gene.
A gene can be associated with multiple causal flows as a member of multiple regulons
| Regulon | Program | # genes | # regulators | # causal flows |
|---|---|---|---|---|
| R-1046 | Pr-1 | 1 | 1 | 2 |
| R-1073 | Pr-1 | 1 | 1 | 4 |
| R-1133 | Pr-1 | 1 | 1 | 8 |
| R-1170 | Pr-1 | 1 | 1 | 4 |
| R-12 | Pr-1 | 1 | 1 | 14 |
| R-1308 | Pr-1 | 1 | 1 | 10 |
| R-1495 | Pr-1 | 1 | 1 | 7 |
| R-1818 | Pr-1 | 1 | 1 | 2 |
| R-1886 | Pr-1 | 1 | 1 | 5 |
| R-1912 | Pr-1 | 1 | 1 | 8 |
| R-2005 | Pr-1 | 1 | 1 | 13 |
| R-2053 | Pr-1 | 1 | 1 | 61 |
| R-2322 | Pr-1 | 1 | 1 | 6 |
| R-2438 | Pr-1 | 1 | 1 | 14 |
| R-2620 | Pr-1 | 1 | 1 | 3 |
| R-2705 | Pr-9 | 1 | 1 | 14 |
| R-2762 | Pr-1 | 1 | 1 | 15 |
| R-2811 | Pr-1 | 1 | 1 | 5 |
| R-2954 | Pr-1 | 1 | 1 | 14 |
| R-3016 | Pr-1 | 1 | 1 | 21 |
| R-3037 | Pr-1 | 1 | 1 | 5 |
| R-3066 | Pr-1 | 1 | 1 | 6 |
| R-3107 | Pr-1 | 1 | 1 | 5 |
| R-3168 | Pr-1 | 1 | 1 | 5 |
| R-3563 | Pr-1 | 1 | 1 | 3 |
| R-385 | Pr-1 | 1 | 1 | 15 |
| R-582 | Pr-1 | 1 | 1 | 6 |
| R-632 | Pr-1 | 1 | 1 | 10 |
| R-646 | Pr-140 | 1 | 1 | 51 |
| R-683 | Pr-1 | 1 | 1 | 14 |
| R-856 | Pr-1 | 1 | 1 | 6 |
| R-980 | Pr-1 | 1 | 1 | 6 |